(28 nodes) ER to Golgi transport vesicle membrane network (Hippocampus comes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	srebf2	Sterol regulatory element binding transcription factor 2. (1122 aa)
	vma21	Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family. (118 aa)
	uso1	USO1 vesicle transport factor. (957 aa)
	sec24b	SEC24 homolog B, COPII coat complex component. (1168 aa)
	pdcd6	Programmed cell death 6. (185 aa)
	Stx17	Uncharacterized protein. (66 aa)
	sec31a	SEC31 homolog A, COPII coat complex component. (1046 aa)
	LOC109512384	Secretion associated, Ras related GTPase 1Ab; Belongs to the small GTPase superfamily. SAR1 family. (248 aa)
	LOC109529737	SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (282 aa)
	KLHL12	Kelch like family member 12. (598 aa)
	sec24a	SEC24 homolog A, COPII coat complex component. (967 aa)
	scap	SREBF chaperone. (1275 aa)
	sec13	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (320 aa)
	sec24d	SEC24 homolog D, COPII coat complex component. (1016 aa)
	vti1a	Vesicle transport through interaction with t-SNAREs 1A. (217 aa)
	LOC109522615	SEC31 homolog B, COPII coat complex component. (1210 aa)
	sar1b	Secretion associated, Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	LOC109522059	BTB domain-containing protein. (512 aa)
	sec24c	SEC24 homolog C, COPII coat complex component. (1292 aa)
	ENSHCOP00000010802	Uncharacterized protein. (182 aa)
	LOC109527453	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (736 aa)
	sec16a	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2114 aa)
	srebf1	Sterol regulatory element binding transcription factor 1. (1179 aa)
	gosr2	Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. (212 aa)
	vti1b	Vesicle transport through interaction with t-SNAREs 1B. (221 aa)
	LOC109520489	SEC22 homolog B, vesicle trafficking protein a; Belongs to the synaptobrevin family. (215 aa)
	sec23a	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (781 aa)
	pef1	Penta-EF-hand domain containing 1. (245 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000010802	LOC109512384	ENSHCOP00000010802	ENSHCOP00000001817	Uncharacterized protein.	Secretion associated, Ras related GTPase 1Ab; Belongs to the small GTPase superfamily. SAR1 family.	0.786
ENSHCOP00000010802	LOC109520489	ENSHCOP00000010802	ENSHCOP00000016766	Uncharacterized protein.	SEC22 homolog B, vesicle trafficking protein a; Belongs to the synaptobrevin family.	0.615
ENSHCOP00000010802	LOC109522615	ENSHCOP00000010802	ENSHCOP00000025825	Uncharacterized protein.	SEC31 homolog B, COPII coat complex component.	0.833
ENSHCOP00000010802	LOC109527453	ENSHCOP00000010802	ENSHCOP00000013229	Uncharacterized protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.920
ENSHCOP00000010802	LOC109529737	ENSHCOP00000010802	ENSHCOP00000021338	Uncharacterized protein.	SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family.	0.615
ENSHCOP00000010802	gosr2	ENSHCOP00000010802	ENSHCOP00000014199	Uncharacterized protein.	Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.	0.690
ENSHCOP00000010802	sar1b	ENSHCOP00000010802	ENSHCOP00000008656	Uncharacterized protein.	Secretion associated, Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family.	0.786
ENSHCOP00000010802	sec13	ENSHCOP00000010802	ENSHCOP00000024059	Uncharacterized protein.	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.	0.974
ENSHCOP00000010802	sec23a	ENSHCOP00000010802	ENSHCOP00000017218	Uncharacterized protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.920
ENSHCOP00000010802	sec24a	ENSHCOP00000010802	ENSHCOP00000022855	Uncharacterized protein.	SEC24 homolog A, COPII coat complex component.	0.920
ENSHCOP00000010802	sec24b	ENSHCOP00000010802	ENSHCOP00000018737	Uncharacterized protein.	SEC24 homolog B, COPII coat complex component.	0.920
ENSHCOP00000010802	sec24c	ENSHCOP00000010802	ENSHCOP00000009574	Uncharacterized protein.	SEC24 homolog C, COPII coat complex component.	0.895
ENSHCOP00000010802	sec24d	ENSHCOP00000010802	ENSHCOP00000024948	Uncharacterized protein.	SEC24 homolog D, COPII coat complex component.	0.895
ENSHCOP00000010802	sec31a	ENSHCOP00000010802	ENSHCOP00000001875	Uncharacterized protein.	SEC31 homolog A, COPII coat complex component.	0.833
ENSHCOP00000010802	uso1	ENSHCOP00000010802	ENSHCOP00000003415	Uncharacterized protein.	USO1 vesicle transport factor.	0.587
KLHL12	pef1	ENSHCOP00000022398	ENSHCOP00000019454	Kelch like family member 12.	Penta-EF-hand domain containing 1.	0.493
LOC109512384	ENSHCOP00000010802	ENSHCOP00000001817	ENSHCOP00000010802	Secretion associated, Ras related GTPase 1Ab; Belongs to the small GTPase superfamily. SAR1 family.	Uncharacterized protein.	0.786
LOC109512384	LOC109520489	ENSHCOP00000001817	ENSHCOP00000016766	Secretion associated, Ras related GTPase 1Ab; Belongs to the small GTPase superfamily. SAR1 family.	SEC22 homolog B, vesicle trafficking protein a; Belongs to the synaptobrevin family.	0.683
LOC109512384	LOC109522615	ENSHCOP00000001817	ENSHCOP00000025825	Secretion associated, Ras related GTPase 1Ab; Belongs to the small GTPase superfamily. SAR1 family.	SEC31 homolog B, COPII coat complex component.	0.989
LOC109512384	LOC109527453	ENSHCOP00000001817	ENSHCOP00000013229	Secretion associated, Ras related GTPase 1Ab; Belongs to the small GTPase superfamily. SAR1 family.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.929