(13 nodes) Terpenoid biosynthetic process network (Hippocampus comes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSHCOP00000002284	RUN domain-containing protein. (116 aa)
	rdh10	Retinol dehydrogenase 10a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (337 aa)
	LOC109522614	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (315 aa)
	LOC109525455	Retinoid isomerohydrolase RPE65 b. (508 aa)
	hmgcs1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (515 aa)
	rbp1	Retinol binding protein 1, cellular, tandem duplicate 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (134 aa)
	lss	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (734 aa)
	rusc1	RUN and SH3 domain containing 1. (528 aa)
	LOC109531429	Retinol dehydrogenase 20; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
	rpe65	Retinoid isomerohydrolase RPE65 a. (531 aa)
	LOC109526921	RUN and SH3 domain containing 2. (1498 aa)
	ggps1	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (307 aa)
	fdps	Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (358 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000002284	ggps1	ENSHCOP00000002284	ENSHCOP00000022439	RUN domain-containing protein.	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.614
ENSHCOP00000002284	hmgcs1	ENSHCOP00000002284	ENSHCOP00000011483	RUN domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.579
ENSHCOP00000002284	lss	ENSHCOP00000002284	ENSHCOP00000020573	RUN domain-containing protein.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.697
ENSHCOP00000002284	rusc1	ENSHCOP00000002284	ENSHCOP00000020856	RUN domain-containing protein.	RUN and SH3 domain containing 1.	0.407
LOC109522614	LOC109525455	ENSHCOP00000003593	ENSHCOP00000007547	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Retinoid isomerohydrolase RPE65 b.	0.909
LOC109522614	rpe65	ENSHCOP00000003593	ENSHCOP00000027322	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Retinoid isomerohydrolase RPE65 a.	0.909
LOC109525455	LOC109522614	ENSHCOP00000007547	ENSHCOP00000003593	Retinoid isomerohydrolase RPE65 b.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.909
LOC109525455	LOC109531429	ENSHCOP00000007547	ENSHCOP00000027012	Retinoid isomerohydrolase RPE65 b.	Retinol dehydrogenase 20; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.909
LOC109525455	rdh10	ENSHCOP00000007547	ENSHCOP00000003354	Retinoid isomerohydrolase RPE65 b.	Retinol dehydrogenase 10a; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.909
LOC109525455	rpe65	ENSHCOP00000007547	ENSHCOP00000027322	Retinoid isomerohydrolase RPE65 b.	Retinoid isomerohydrolase RPE65 a.	0.901
LOC109526921	ggps1	ENSHCOP00000021719	ENSHCOP00000022439	RUN and SH3 domain containing 2.	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.614
LOC109526921	hmgcs1	ENSHCOP00000021719	ENSHCOP00000011483	RUN and SH3 domain containing 2.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.579
LOC109526921	lss	ENSHCOP00000021719	ENSHCOP00000020573	RUN and SH3 domain containing 2.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.697
LOC109526921	rusc1	ENSHCOP00000021719	ENSHCOP00000020856	RUN and SH3 domain containing 2.	RUN and SH3 domain containing 1.	0.407
LOC109531429	LOC109525455	ENSHCOP00000027012	ENSHCOP00000007547	Retinol dehydrogenase 20; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Retinoid isomerohydrolase RPE65 b.	0.909
LOC109531429	rpe65	ENSHCOP00000027012	ENSHCOP00000027322	Retinol dehydrogenase 20; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Retinoid isomerohydrolase RPE65 a.	0.909
fdps	ggps1	ENSHCOP00000020866	ENSHCOP00000022439	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.978
fdps	hmgcs1	ENSHCOP00000020866	ENSHCOP00000011483	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.976
fdps	lss	ENSHCOP00000020866	ENSHCOP00000020573	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.796
fdps	rusc1	ENSHCOP00000020866	ENSHCOP00000020856	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	RUN and SH3 domain containing 1.	0.454