32 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lrp6	Low density lipoprotein receptor-related protein 6. (1518 aa)
	Fzd2	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa)
	LOC109518923	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (590 aa)
	fzd9	Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
	TRABD2A	TraB domain containing 2A. (346 aa)
	Fzd10	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (567 aa)
	fzd6	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (678 aa)
	LOC109525531	Uncharacterized protein. (324 aa)
	ryk	Receptor like tyrosine kinase. (597 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (531 aa)
	LOC109510414	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
	APCDD1	APC down-regulated 1. (502 aa)
	LOC109528448	Uncharacterized protein; Belongs to the membrane-bound acyltransferase family. (447 aa)
	porcn	Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (450 aa)
	fjx1	Four-jointed box kinase 1. (416 aa)
	ror1	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (886 aa)
	LOC109529816	Sizzled. (281 aa)
	frzb	Frizzled related protein. (314 aa)
	LOC109508455	Adenomatosis polyposis coli down-regulated 1-like. (506 aa)
	fzd8	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	ENSHCOP00000015931	Ig-like domain-containing protein. (132 aa)
	FZD7	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (525 aa)
	LOC109528579	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (704 aa)
	sfrp5	Secreted frizzled-related protein 5. (321 aa)
	fzd3	Frizzled class receptor 3a; Belongs to the G-protein coupled receptor Fz/Smo family. (689 aa)
	sfrp1	Secreted frizzled-related protein 1a. (310 aa)
	sfrp2	Secreted frizzled-related protein 2. (299 aa)
	ENSHCOP00000027545	TraB domain containing 2B. (479 aa)
	wls	Wnt ligand secretion mediator. (532 aa)
	cthrc1	Collagen triple helix repeat containing 1b. (231 aa)
	ror2	Receptor tyrosine kinase-like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (915 aa)
	LOC109512258	Uncharacterized protein. (652 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APCDD1	lrp6	ENSHCOP00000024369	ENSHCOP00000005119	APC down-regulated 1.	Low density lipoprotein receptor-related protein 6.	0.412
ENSHCOP00000015931	FZD7	ENSHCOP00000015931	ENSHCOP00000015021	Ig-like domain-containing protein.	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	0.444
ENSHCOP00000015931	Fzd10	ENSHCOP00000015931	ENSHCOP00000011441	Ig-like domain-containing protein.	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.	0.403
ENSHCOP00000015931	Fzd2	ENSHCOP00000015931	ENSHCOP00000006032	Ig-like domain-containing protein.	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.	0.444
ENSHCOP00000015931	LOC109510414	ENSHCOP00000015931	ENSHCOP00000001656	Ig-like domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.444
ENSHCOP00000015931	LOC109512258	ENSHCOP00000015931	ENSHCOP00000024534	Ig-like domain-containing protein.	Uncharacterized protein.	0.444
ENSHCOP00000015931	LOC109518923	ENSHCOP00000015931	ENSHCOP00000008742	Ig-like domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.444
ENSHCOP00000015931	LOC109525531	ENSHCOP00000015931	ENSHCOP00000011682	Ig-like domain-containing protein.	Uncharacterized protein.	0.402
ENSHCOP00000015931	fzd4	ENSHCOP00000015931	ENSHCOP00000012037	Ig-like domain-containing protein.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.454
ENSHCOP00000015931	fzd8	ENSHCOP00000015931	ENSHCOP00000016529	Ig-like domain-containing protein.	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	0.444
ENSHCOP00000015931	fzd9	ENSHCOP00000015931	ENSHCOP00000010638	Ig-like domain-containing protein.	Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family.	0.403
ENSHCOP00000015931	sfrp2	ENSHCOP00000015931	ENSHCOP00000005098	Ig-like domain-containing protein.	Secreted frizzled-related protein 2.	0.402
FZD7	ENSHCOP00000015931	ENSHCOP00000015021	ENSHCOP00000015931	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Ig-like domain-containing protein.	0.444
FZD7	LOC109525531	ENSHCOP00000015021	ENSHCOP00000011682	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.685
FZD7	fzd4	ENSHCOP00000015021	ENSHCOP00000012037	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.411
FZD7	lrp6	ENSHCOP00000015021	ENSHCOP00000005119	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Low density lipoprotein receptor-related protein 6.	0.956
FZD7	ror1	ENSHCOP00000015021	ENSHCOP00000020067	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.797
FZD7	ror2	ENSHCOP00000015021	ENSHCOP00000024611	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor tyrosine kinase-like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.797
FZD7	sfrp1	ENSHCOP00000015021	ENSHCOP00000004959	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 1a.	0.691
FZD7	sfrp2	ENSHCOP00000015021	ENSHCOP00000005098	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 2.	0.685