STRINGSTRING
LOC109524165 LOC109524165 bmpr2 bmpr2 LOC109516609 LOC109516609 ENSHCOP00000011367 ENSHCOP00000011367 DAG1 DAG1 ppp3r1 ppp3r1 LOC109517974 LOC109517974 hspb11 hspb11 LOC109510758 LOC109510758 ctsz ctsz hps1 hps1 timeless timeless pkd1 pkd1 itgb6 itgb6 LOC109517348 LOC109517348 ENSHCOP00000016441 ENSHCOP00000016441 srf srf dlg5 dlg5 hhip hhip LOC109515764 LOC109515764 stk40 stk40 LOC109510605 LOC109510605 ENSHCOP00000020681 ENSHCOP00000020681 bag6 bag6 ENSHCOP00000021302 ENSHCOP00000021302 aimp2 aimp2 atxn1l atxn1l igfbp5 igfbp5 LOC109517076 LOC109517076 ENSHCOP00000001552 ENSHCOP00000001552 fgf7 fgf7 ENSHCOP00000024644 ENSHCOP00000024644 LOC109514850 LOC109514850 zfpm2 zfpm2 LOC109518807 LOC109518807 adamtsl2 adamtsl2 phf14 phf14 pkdcc pkdcc LOC109515444 LOC109515444 sav1 sav1 LOC109530100 LOC109530100 ENSHCOP00000027596 ENSHCOP00000027596 PTK7 PTK7 ENSHCOP00000002689 ENSHCOP00000002689 fgf2 fgf2 LOC109519656 LOC109519656 slc7a11 slc7a11 WNT2B WNT2B tcf21 tcf21 TGFBR2 TGFBR2 ENSHCOP00000007650 ENSHCOP00000007650 tab1 tab1 LOC109512841 LOC109512841 ENSHCOP00000007924 ENSHCOP00000007924 LOC109526244 LOC109526244 SP3 SP3 LOC109515023 LOC109515023 phex phex SRF SRF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC109524165Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (279 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (492 aa)
LOC109516609Integrin, alpha 3b; Belongs to the integrin alpha chain family. (1011 aa)
ENSHCOP00000011367PLAT domain-containing protein. (274 aa)
DAG1Dystroglycan 1. (850 aa)
ppp3r1Uncharacterized protein. (170 aa)
LOC109517974Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (173 aa)
hspb11Zgc:158640. (139 aa)
LOC109510758Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
ctszCathepsin Z; Belongs to the peptidase C1 family. (313 aa)
hps1HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (660 aa)
timelessTimeless circadian clock. (1222 aa)
pkd1Polycystic kidney disease 1a. (4575 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (775 aa)
LOC109517348Sp3b transcription factor. (632 aa)
ENSHCOP00000016441ERBB receptor feedback inhibitor 1a. (275 aa)
srfSerum response factor b. (601 aa)
dlg5Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (1860 aa)
hhipHedgehog interacting protein. (679 aa)
LOC109515764Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins [...] (163 aa)
stk40Serine/threonine kinase 40. (440 aa)
LOC109510605Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
ENSHCOP00000020681Uncharacterized protein. (116 aa)
bag6BCL2 associated athanogene 6. (1219 aa)
ENSHCOP00000021302Uncharacterized protein. (668 aa)
aimp2Aminoacyl tRNA synthetase complex interacting multifunctional protein 2. (319 aa)
atxn1lAtaxin 1-like. (800 aa)
igfbp5Insulin-like growth factor binding protein 5a. (256 aa)
LOC109517076Ring finger and CCCH-type domains 2. (1123 aa)
ENSHCOP00000001552Uncharacterized protein. (133 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa)
ENSHCOP00000024644annotation not available (274 aa)
LOC109514850E1A binding protein p300 b. (2669 aa)
zfpm2Zinc finger protein, FOG family member 2a. (1096 aa)
LOC109518807Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (205 aa)
adamtsl2ADAMTS-like 2. (867 aa)
phf14PHD finger protein 14. (842 aa)
pkdccProtein kinase domain containing, cytoplasmic b. (505 aa)
LOC109515444Insulin-like growth factor binding protein 5a. (268 aa)
sav1Salvador family WW domain containing protein 1. (403 aa)
LOC109530100Si:ch73-352p4.8. (478 aa)
ENSHCOP00000027596Noggin; Belongs to the noggin family. (222 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1058 aa)
ENSHCOP00000002689Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (159 aa)
LOC109519656Uncharacterized protein. (661 aa)
slc7a11Solute carrier family 7 member 11. (493 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
tcf21Transcription factor 21. (159 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (562 aa)
ENSHCOP00000007650Sprouty RTK signaling antagonist 2. (283 aa)
tab1TGF-beta activated kinase 1/MAP3K7 binding protein 1. (494 aa)
LOC109512841E1A binding protein p300 a. (2561 aa)
ENSHCOP00000007924Protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b. (70 aa)
LOC109526244Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (314 aa)
SP3Sp3a transcription factor. (668 aa)
LOC109515023Peptidase S72 domain-containing protein. (880 aa)
phexPhosphate regulating endopeptidase homolog, X-linked. (742 aa)
SRFSerum response factor. (344 aa)
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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