42 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109531720	ADAM metallopeptidase domain 17b. (805 aa)
	wfikkn2	Info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a. (574 aa)
	ldlrad4	Low density lipoprotein receptor class A domain containing 4b. (279 aa)
	prdm16	Si:ch211-263k4.2. (1339 aa)
	tdp2	Tyrosyl-DNA phosphodiesterase 2b. (367 aa)
	LOC109508199	Elastin microfibril interfacer 1b. (1025 aa)
	LOC109527381	HtrA serine peptidase 3a. (430 aa)
	spred3	Sprouty related EVH1 domain containing 3. (504 aa)
	LOC109514222	Negative regulator of reactive oxygen species. (678 aa)
	adamtsl2	ADAMTS-like 2. (867 aa)
	znf451	Zinc finger protein 451. (851 aa)
	Mecom	Uncharacterized protein. (127 aa)
	bcl9l	Bcl9 like. (1418 aa)
	smad7	Mothers against decapentaplegic homolog. (593 aa)
	pin1	Peptidyl-prolyl cis-trans isomerase. (157 aa)
	LOC109507925	Golgi glycoprotein 1a. (1156 aa)
	ENSHCOP00000021173	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (165 aa)
	LOC109532299	Leucine rich repeat and Ig domain containing 3a. (610 aa)
	skil	SKI-like proto-oncogene a. (685 aa)
	hspa5	Heat shock protein 5; Belongs to the heat shock protein 70 family. (650 aa)
	LOC109508124	Elastin microfibril interfacer 1a. (1022 aa)
	snx25	Sorting nexin 25. (974 aa)
	ENSHCOP00000002881	Sprouty homolog 1, antagonist of FGF signaling (Drosophila). (314 aa)
	LOC109523155	Sirtuin 1. (657 aa)
	WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (572 aa)
	lemd3	LEM domain containing 3. (804 aa)
	ENSHCOP00000007650	Sprouty RTK signaling antagonist 2. (283 aa)
	ENSHCOP00000009872	Prostate transmembrane protein, androgen induced 1. (202 aa)
	strap	Serine/threonine kinase receptor associated protein. (329 aa)
	pbld	Phenazine biosynthesis like protein domain containing. (277 aa)
	ENSHCOP00000011529	SKI proto-oncogene. (235 aa)
	ski	V-ski avian sarcoma viral oncogene homolog a. (730 aa)
	smad6	Mothers against decapentaplegic homolog. (481 aa)
	ywhaq	ADAM metallopeptidase domain 17a. (883 aa)
	wfikkn1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (597 aa)
	bambi	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a. (306 aa)
	LOC109531487	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (186 aa)
	LOC109529233	V-ski avian sarcoma viral oncogene homolog b. (678 aa)
	LOC109507415	Ig-like domain-containing protein. (564 aa)
	ENSHCOP00000019285	Deacetylase sirtuin-type domain-containing protein. (166 aa)
	ENSHCOP00000019306	Sirtuin 1. (369 aa)
	LOC109514327	Uncharacterized protein. (1140 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000002881	ENSHCOP00000007650	ENSHCOP00000002881	ENSHCOP00000007650	Sprouty homolog 1, antagonist of FGF signaling (Drosophila).	Sprouty RTK signaling antagonist 2.	0.622
ENSHCOP00000007650	ENSHCOP00000002881	ENSHCOP00000007650	ENSHCOP00000002881	Sprouty RTK signaling antagonist 2.	Sprouty homolog 1, antagonist of FGF signaling (Drosophila).	0.622
ENSHCOP00000011529	skil	ENSHCOP00000011529	ENSHCOP00000001715	SKI proto-oncogene.	SKI-like proto-oncogene a.	0.603
ENSHCOP00000011529	smad6	ENSHCOP00000011529	ENSHCOP00000012058	SKI proto-oncogene.	Mothers against decapentaplegic homolog.	0.420
ENSHCOP00000011529	smad7	ENSHCOP00000011529	ENSHCOP00000023338	SKI proto-oncogene.	Mothers against decapentaplegic homolog.	0.420
LOC109507925	LOC109514327	ENSHCOP00000021786	ENSHCOP00000020921	Golgi glycoprotein 1a.	Uncharacterized protein.	0.900
LOC109514327	LOC109507925	ENSHCOP00000020921	ENSHCOP00000021786	Uncharacterized protein.	Golgi glycoprotein 1a.	0.900
LOC109529233	smad6	ENSHCOP00000016834	ENSHCOP00000012058	V-ski avian sarcoma viral oncogene homolog b.	Mothers against decapentaplegic homolog.	0.402
LOC109529233	smad7	ENSHCOP00000016834	ENSHCOP00000023338	V-ski avian sarcoma viral oncogene homolog b.	Mothers against decapentaplegic homolog.	0.402
LOC109531720	ywhaq	ENSHCOP00000020849	ENSHCOP00000012813	ADAM metallopeptidase domain 17b.	ADAM metallopeptidase domain 17a.	0.902
bambi	smad6	ENSHCOP00000014231	ENSHCOP00000012058	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a.	Mothers against decapentaplegic homolog.	0.749
bambi	smad7	ENSHCOP00000014231	ENSHCOP00000023338	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a.	Mothers against decapentaplegic homolog.	0.749
pbld	strap	ENSHCOP00000011493	ENSHCOP00000009913	Phenazine biosynthesis like protein domain containing.	Serine/threonine kinase receptor associated protein.	0.691
ski	skil	ENSHCOP00000011533	ENSHCOP00000001715	V-ski avian sarcoma viral oncogene homolog a.	SKI-like proto-oncogene a.	0.600
ski	smad6	ENSHCOP00000011533	ENSHCOP00000012058	V-ski avian sarcoma viral oncogene homolog a.	Mothers against decapentaplegic homolog.	0.420
ski	smad7	ENSHCOP00000011533	ENSHCOP00000023338	V-ski avian sarcoma viral oncogene homolog a.	Mothers against decapentaplegic homolog.	0.420
skil	ENSHCOP00000011529	ENSHCOP00000001715	ENSHCOP00000011529	SKI-like proto-oncogene a.	SKI proto-oncogene.	0.603
skil	ski	ENSHCOP00000001715	ENSHCOP00000011533	SKI-like proto-oncogene a.	V-ski avian sarcoma viral oncogene homolog a.	0.600
skil	smad6	ENSHCOP00000001715	ENSHCOP00000012058	SKI-like proto-oncogene a.	Mothers against decapentaplegic homolog.	0.512
skil	smad7	ENSHCOP00000001715	ENSHCOP00000023338	SKI-like proto-oncogene a.	Mothers against decapentaplegic homolog.	0.512