(12 nodes) Beta-catenin destruction complex network (Hippocampus comes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ctnnbip1	Catenin, beta interacting protein 1. (81 aa)
	axin1	Axin 1. (786 aa)
	LOC109511398	Uncharacterized protein. (887 aa)
	ENSHCOP00000019246	APC_N_CC domain-containing protein. (229 aa)
	LOC109531651	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
	LOC109515107	Axin 2 (conductin, axil). (831 aa)
	LOC109518393	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (439 aa)
	AXIN2	Axin 2. (802 aa)
	ENSHCOP00000028303	APC_N_CC domain-containing protein. (239 aa)
	ENSHCOP00000026938	Uncharacterized protein. (102 aa)
	cacybp	Calcyclin binding protein. (228 aa)
	gsk3b	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (421 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	ENSHCOP00000019246	ENSHCOP00000010703	ENSHCOP00000019246	Axin 2.	APC_N_CC domain-containing protein.	0.813
AXIN2	ENSHCOP00000026938	ENSHCOP00000010703	ENSHCOP00000026938	Axin 2.	Uncharacterized protein.	0.796
AXIN2	ENSHCOP00000028303	ENSHCOP00000010703	ENSHCOP00000028303	Axin 2.	APC_N_CC domain-containing protein.	0.813
AXIN2	LOC109511398	ENSHCOP00000010703	ENSHCOP00000006745	Axin 2.	Uncharacterized protein.	0.924
AXIN2	LOC109515107	ENSHCOP00000010703	ENSHCOP00000014262	Axin 2.	Axin 2 (conductin, axil).	0.902
AXIN2	LOC109518393	ENSHCOP00000010703	ENSHCOP00000004590	Axin 2.	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	0.774
AXIN2	LOC109531651	ENSHCOP00000010703	ENSHCOP00000009486	Axin 2.	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	0.774
AXIN2	gsk3b	ENSHCOP00000010703	ENSHCOP00000003907	Axin 2.	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.	0.978
ENSHCOP00000019246	AXIN2	ENSHCOP00000019246	ENSHCOP00000010703	APC_N_CC domain-containing protein.	Axin 2.	0.813
ENSHCOP00000019246	ENSHCOP00000026938	ENSHCOP00000019246	ENSHCOP00000026938	APC_N_CC domain-containing protein.	Uncharacterized protein.	0.784
ENSHCOP00000019246	LOC109511398	ENSHCOP00000019246	ENSHCOP00000006745	APC_N_CC domain-containing protein.	Uncharacterized protein.	0.815
ENSHCOP00000019246	LOC109515107	ENSHCOP00000019246	ENSHCOP00000014262	APC_N_CC domain-containing protein.	Axin 2 (conductin, axil).	0.813
ENSHCOP00000019246	LOC109518393	ENSHCOP00000019246	ENSHCOP00000004590	APC_N_CC domain-containing protein.	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	0.784
ENSHCOP00000019246	LOC109531651	ENSHCOP00000019246	ENSHCOP00000009486	APC_N_CC domain-containing protein.	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	0.784
ENSHCOP00000019246	axin1	ENSHCOP00000019246	ENSHCOP00000005032	APC_N_CC domain-containing protein.	Axin 1.	0.815
ENSHCOP00000019246	ctnnbip1	ENSHCOP00000019246	ENSHCOP00000012521	APC_N_CC domain-containing protein.	Catenin, beta interacting protein 1.	0.617
ENSHCOP00000019246	gsk3b	ENSHCOP00000019246	ENSHCOP00000003907	APC_N_CC domain-containing protein.	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.	0.784
ENSHCOP00000026938	AXIN2	ENSHCOP00000026938	ENSHCOP00000010703	Uncharacterized protein.	Axin 2.	0.796
ENSHCOP00000026938	ENSHCOP00000019246	ENSHCOP00000026938	ENSHCOP00000019246	Uncharacterized protein.	APC_N_CC domain-containing protein.	0.784
ENSHCOP00000026938	ENSHCOP00000028303	ENSHCOP00000026938	ENSHCOP00000028303	Uncharacterized protein.	APC_N_CC domain-containing protein.	0.784