(28 nodes) Notochord development network (Hippocampus comes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	vps18	VPS18 core subunit of CORVET and HOPS complexes. (982 aa)
	LOC109524221	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (332 aa)
	LOC109524189	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
	LOC109516582	Zinc finger protein 219. (634 aa)
	LOC109514581	T-box transcription factor Ta. (429 aa)
	bmp2	Bone morphogenetic protein 2b. (393 aa)
	ENSHCOP00000021111	T-box transcription factor 2a. (360 aa)
	LOC109521090	Ephrin-A1b; Belongs to the ephrin family. (233 aa)
	LOC109523037	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	lamc1	Laminin, gamma 1. (1472 aa)
	ENSHCOP00000027596	Noggin; Belongs to the noggin family. (222 aa)
	crim1	Uncharacterized protein. (934 aa)
	LOC109521915	Cordon-bleu WH2 repeat protein. (1443 aa)
	copb1	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (953 aa)
	LOC109514620	Ephrin-A1a; Belongs to the ephrin family. (226 aa)
	TBX2	T-box transcription factor 2. (675 aa)
	LOC109528135	Notochord homeobox. (230 aa)
	LOC109520893	Lysine (K)-specific demethylase 6A, like. (1335 aa)
	ENSHCOP00000009828	Forkhead box H1. (494 aa)
	VANGL2	Vang-like protein. (527 aa)
	ENSHCOP00000010989	Uncharacterized protein. (96 aa)
	ctps1	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (599 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (186 aa)
	ppp1r35	PPP1R35_C domain-containing protein. (185 aa)
	mib1	Mindbomb E3 ubiquitin protein ligase 1. (995 aa)
	kdm6a	Lysine (K)-specific demethylase 6A. (1205 aa)
	id3	Inhibitor of DNA binding 3. (115 aa)
	slc2a10	Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (512 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000009828	LOC109514581	ENSHCOP00000009828	ENSHCOP00000018427	Forkhead box H1.	T-box transcription factor Ta.	0.580
ENSHCOP00000027596	bmp2	ENSHCOP00000027596	ENSHCOP00000019258	Noggin; Belongs to the noggin family.	Bone morphogenetic protein 2b.	0.798
LOC109514581	ENSHCOP00000009828	ENSHCOP00000018427	ENSHCOP00000009828	T-box transcription factor Ta.	Forkhead box H1.	0.580
LOC109514581	LOC109523037	ENSHCOP00000018427	ENSHCOP00000022017	T-box transcription factor Ta.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.529
LOC109514581	LOC109528135	ENSHCOP00000018427	ENSHCOP00000008940	T-box transcription factor Ta.	Notochord homeobox.	0.729
LOC109520893	ctps1	ENSHCOP00000009091	ENSHCOP00000012608	Lysine (K)-specific demethylase 6A, like.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.574
LOC109523037	LOC109514581	ENSHCOP00000022017	ENSHCOP00000018427	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	T-box transcription factor Ta.	0.529
LOC109528135	LOC109514581	ENSHCOP00000008940	ENSHCOP00000018427	Notochord homeobox.	T-box transcription factor Ta.	0.729
bmp2	ENSHCOP00000027596	ENSHCOP00000019258	ENSHCOP00000027596	Bone morphogenetic protein 2b.	Noggin; Belongs to the noggin family.	0.798
ctps1	LOC109520893	ENSHCOP00000012608	ENSHCOP00000009091	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Lysine (K)-specific demethylase 6A, like.	0.574
ctps1	kdm6a	ENSHCOP00000012608	ENSHCOP00000014215	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Lysine (K)-specific demethylase 6A.	0.574
kdm6a	ctps1	ENSHCOP00000014215	ENSHCOP00000012608	Lysine (K)-specific demethylase 6A.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.574