STRINGSTRING
dnmt1 dnmt1 LOC109523155 LOC109523155 ENSHCOP00000007765 ENSHCOP00000007765 kdm4a kdm4a kdm1a kdm1a LOC109518926 LOC109518926 kdm4c kdm4c jarid2 jarid2 LOC109519046 LOC109519046 ENSHCOP00000019306 ENSHCOP00000019306 ENSHCOP00000019285 ENSHCOP00000019285 brca1 brca1 fh fh prmt6 prmt6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dnmt1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1485 aa)
LOC109523155Sirtuin 1. (657 aa)
ENSHCOP00000007765S1 motif domain-containing protein. (480 aa)
kdm4aLysine (K)-specific demethylase 4A, genome duplicate a. (1022 aa)
kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (839 aa)
LOC109518926Uncharacterized protein. (1119 aa)
kdm4cLysine (K)-specific demethylase 4C. (1618 aa)
jarid2Jumonji, AT rich interactive domain 2b. (1258 aa)
LOC109519046Lysine (K)-specific demethylase 4B. (1046 aa)
ENSHCOP00000019306Sirtuin 1. (369 aa)
ENSHCOP00000019285Deacetylase sirtuin-type domain-containing protein. (166 aa)
brca1Uncharacterized protein. (1141 aa)
fhFumarate hydratase. (499 aa)
prmt6Protein arginine methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (349 aa)
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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