27 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109512841	E1A binding protein p300 a. (2561 aa)
	LOC109506870	CULLIN_2 domain-containing protein; Belongs to the cullin family. (215 aa)
	serf2	Small EDRK-rich factor 2. (62 aa)
	xbp1	X-box binding protein 1. (262 aa)
	LOC109514850	E1A binding protein p300 b. (2669 aa)
	utp25	UTP25 small subunit processor component. (753 aa)
	LOC109532549	CREB binding protein b. (1735 aa)
	ENSHCOP00000019306	Sirtuin 1. (369 aa)
	ENSHCOP00000019285	Deacetylase sirtuin-type domain-containing protein. (166 aa)
	LOC109527342	CREB binding protein a. (2447 aa)
	LOC109531321	Nuclear receptor subfamily 1, group D, member 4a. (571 aa)
	isoc2	Isochorismatase domain containing 2. (197 aa)
	htt	Huntingtin. (2861 aa)
	rnf139	Ring finger protein 139. (698 aa)
	ENSHCOP00000014561	VHS domain-containing protein. (126 aa)
	fbxw11	F-box and WD repeat domain containing 11b. (527 aa)
	CUL3	Cullin 3; Belongs to the cullin family. (767 aa)
	fbxo4	F-box protein 4. (364 aa)
	pex2	Peroxisomal biogenesis factor 2. (313 aa)
	derl1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (257 aa)
	gga3	Golgi associated, gamma adaptin ear containing, ARF binding protein 3b. (715 aa)
	ENSHCOP00000006772	Uncharacterized protein. (615 aa)
	LOC109532526	Uncharacterized protein. (1579 aa)
	mul1	Mitochondrial E3 ubiquitin protein ligase 1b. (352 aa)
	LOC109523155	Sirtuin 1. (657 aa)
	cdc73	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (547 aa)
	sirt6	Sirtuin 6. (347 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL3	fbxo4	ENSHCOP00000011154	ENSHCOP00000010965	Cullin 3; Belongs to the cullin family.	F-box protein 4.	0.709
CUL3	fbxw11	ENSHCOP00000011154	ENSHCOP00000011653	Cullin 3; Belongs to the cullin family.	F-box and WD repeat domain containing 11b.	0.962
ENSHCOP00000006772	ENSHCOP00000019285	ENSHCOP00000006772	ENSHCOP00000019285	Uncharacterized protein.	Deacetylase sirtuin-type domain-containing protein.	0.400
ENSHCOP00000006772	ENSHCOP00000019306	ENSHCOP00000006772	ENSHCOP00000019306	Uncharacterized protein.	Sirtuin 1.	0.400
ENSHCOP00000006772	LOC109512841	ENSHCOP00000006772	ENSHCOP00000007909	Uncharacterized protein.	E1A binding protein p300 a.	0.854
ENSHCOP00000006772	LOC109514850	ENSHCOP00000006772	ENSHCOP00000024673	Uncharacterized protein.	E1A binding protein p300 b.	0.854
ENSHCOP00000006772	LOC109523155	ENSHCOP00000006772	ENSHCOP00000003219	Uncharacterized protein.	Sirtuin 1.	0.400
ENSHCOP00000006772	LOC109532549	ENSHCOP00000006772	ENSHCOP00000021630	Uncharacterized protein.	CREB binding protein b.	0.925
ENSHCOP00000006772	htt	ENSHCOP00000006772	ENSHCOP00000015436	Uncharacterized protein.	Huntingtin.	0.665
ENSHCOP00000019285	ENSHCOP00000006772	ENSHCOP00000019285	ENSHCOP00000006772	Deacetylase sirtuin-type domain-containing protein.	Uncharacterized protein.	0.400
ENSHCOP00000019285	LOC109512841	ENSHCOP00000019285	ENSHCOP00000007909	Deacetylase sirtuin-type domain-containing protein.	E1A binding protein p300 a.	0.442
ENSHCOP00000019285	LOC109514850	ENSHCOP00000019285	ENSHCOP00000024673	Deacetylase sirtuin-type domain-containing protein.	E1A binding protein p300 b.	0.442
ENSHCOP00000019285	LOC109527342	ENSHCOP00000019285	ENSHCOP00000017333	Deacetylase sirtuin-type domain-containing protein.	CREB binding protein a.	0.400
ENSHCOP00000019285	LOC109532526	ENSHCOP00000019285	ENSHCOP00000006363	Deacetylase sirtuin-type domain-containing protein.	Uncharacterized protein.	0.400
ENSHCOP00000019285	LOC109532549	ENSHCOP00000019285	ENSHCOP00000021630	Deacetylase sirtuin-type domain-containing protein.	CREB binding protein b.	0.400
ENSHCOP00000019285	sirt6	ENSHCOP00000019285	ENSHCOP00000000544	Deacetylase sirtuin-type domain-containing protein.	Sirtuin 6.	0.430
ENSHCOP00000019306	ENSHCOP00000006772	ENSHCOP00000019306	ENSHCOP00000006772	Sirtuin 1.	Uncharacterized protein.	0.400
ENSHCOP00000019306	LOC109512841	ENSHCOP00000019306	ENSHCOP00000007909	Sirtuin 1.	E1A binding protein p300 a.	0.442
ENSHCOP00000019306	LOC109514850	ENSHCOP00000019306	ENSHCOP00000024673	Sirtuin 1.	E1A binding protein p300 b.	0.442
ENSHCOP00000019306	LOC109527342	ENSHCOP00000019306	ENSHCOP00000017333	Sirtuin 1.	CREB binding protein a.	0.400