STRINGSTRING
cul4a cul4a stk11 stk11 tmem161a tmem161a usp47 usp47 mettl3 mettl3 dhx36 dhx36 LOC109507207 LOC109507207 LOC109510475 LOC109510475 LOC109523155 LOC109523155 eif2s1 eif2s1 tp53inp1 tp53inp1 opn3 opn3 noc2l noc2l casp9 casp9 xpc xpc zbtb1 zbtb1 LOC109531756 LOC109531756 ENSHCOP00000006047 ENSHCOP00000006047 LOC109532526 LOC109532526 ENSHCOP00000006772 ENSHCOP00000006772 LOC109522222 LOC109522222 LOC109512841 LOC109512841 pold3 pold3 cops9 cops9 kdm1a kdm1a LOC109524107 LOC109524107 Polk Polk cul4b cul4b ercc1 ercc1 ENSHCOP00000014556 ENSHCOP00000014556 aqp1 aqp1 smpd1 smpd1 ddb1 ddb1 EIF2AK4 EIF2AK4 xpa xpa LOC109527342 LOC109527342 ino80 ino80 LOC109512331 LOC109512331 actr5 actr5 ENSHCOP00000019285 ENSHCOP00000019285 ENSHCOP00000019306 ENSHCOP00000019306 LOC109515948 LOC109515948 LOC109508060 LOC109508060 LOC109532549 LOC109532549 ppid ppid parp1 parp1 LOC109514850 LOC109514850 pold1 pold1 Atr Atr ercc4 ercc4 LOC109526648 LOC109526648 Mc1r Mc1r impact impact bax bax polh polh bmf bmf chek1 chek1 rhbdd1 rhbdd1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cul4aCullin 4A; Belongs to the cullin family. (749 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (430 aa)
tmem161aTransmembrane protein 161A. (487 aa)
usp47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1363 aa)
mettl3Methyltransferase like 3; Belongs to the MT-A70-like family. (575 aa)
dhx36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (966 aa)
LOC109507207Opsin 8, group member b; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (339 aa)
LOC109510475Mitogen-activated protein kinase. (360 aa)
LOC109523155Sirtuin 1. (657 aa)
eif2s1Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
tp53inp1Tumor protein p53 inducible nuclear protein 1. (282 aa)
opn3Opsin 3. (385 aa)
noc2lNOC2-like nucleolar associated transcriptional repressor. (760 aa)
casp9Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (477 aa)
xpcXeroderma pigmentosum, complementation group C. (859 aa)
zbtb1Zinc finger and BTB domain containing 1. (626 aa)
LOC109531756Opsin 5; Belongs to the G-protein coupled receptor 1 family. (334 aa)
ENSHCOP00000006047Uncharacterized protein. (205 aa)
LOC109532526Uncharacterized protein. (1579 aa)
ENSHCOP00000006772Uncharacterized protein. (615 aa)
LOC109522222Mitogen-activated protein kinase. (449 aa)
LOC109512841E1A binding protein p300 a. (2561 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (437 aa)
cops9COP9 signalosome subunit 9. (57 aa)
kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (839 aa)
LOC109524107Nuclear factor of activated T cells 4. (805 aa)
PolkPolymerase (DNA directed) kappa. (396 aa)
cul4bCullin 4B; Belongs to the cullin family. (772 aa)
ercc1Excision repair cross-complementation group 1. (338 aa)
ENSHCOP00000014556Uncharacterized protein. (241 aa)
aqp1Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (259 aa)
smpd1Sphingomyelin phosphodiesterase 1, acid lysosomal. (510 aa)
ddb1Damage-specific DNA binding protein 1. (1093 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1478 aa)
xpaXeroderma pigmentosum, complementation group A. (279 aa)
LOC109527342CREB binding protein a. (2447 aa)
ino80INO80 complex ATPase subunit. (1543 aa)
LOC109512331UmuC domain-containing protein. (184 aa)
actr5Actin related protein 5; Belongs to the actin family. (595 aa)
ENSHCOP00000019285Deacetylase sirtuin-type domain-containing protein. (166 aa)
ENSHCOP00000019306Sirtuin 1. (369 aa)
LOC109515948Aurora kinase B; Belongs to the protein kinase superfamily. (330 aa)
LOC109508060Zgc:153993. (204 aa)
LOC109532549CREB binding protein b. (1735 aa)
ppidPeptidylprolyl isomerase D. (375 aa)
parp1Poly [ADP-ribose] polymerase. (1020 aa)
LOC109514850E1A binding protein p300 b. (2669 aa)
pold1DNA polymerase. (1105 aa)
AtrUncharacterized protein. (106 aa)
ercc4Excision repair cross-complementation group 4. (900 aa)
LOC109526648Mitogen-activated protein kinase. (354 aa)
Mc1rMelanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (322 aa)
impactImpact RWD domain protein. (312 aa)
baxBCL2 associated X, apoptosis regulator a. (255 aa)
polhPolymerase (DNA directed), eta. (483 aa)
bmfBcl2 modifying factor. (135 aa)
chek1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (462 aa)
rhbdd1Rhomboid domain containing 1. (328 aa)
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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