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LOC109510228 LOC109510228 vkorc1l1 vkorc1l1 park7 park7 GLO1 GLO1 LOC109520617 LOC109520617 coq6 coq6 ndufa9 ndufa9 CBR1 CBR1 coq9 coq9 kynu kynu LOC109513382 LOC109513382 LOC109528900 LOC109528900 ENSHCOP00000021915 ENSHCOP00000021915 ENSHCOP00000022354 ENSHCOP00000022354 aadat aadat LOC109523501 LOC109523501 tdo2 tdo2 kyat3 kyat3 coq2 coq2 aldh8a1 aldh8a1 LOC109513814 LOC109513814 hsd11b2 hsd11b2 nqo1 nqo1 kmo kmo got2 got2 coq4 coq4 kdsr kdsr LOC109524363 LOC109524363 ENSHCOP00000001884 ENSHCOP00000001884 kyat1 kyat1 sirt6 sirt6 LOC109516617 LOC109516617 afmid afmid glod4 glod4 hagh hagh LOC109525131 LOC109525131 ubiad1 ubiad1 LOC109523335 LOC109523335 LOC109524007 LOC109524007 cryzl1 cryzl1 gatd1 gatd1 pdss2 pdss2 srd5a2 srd5a2 pdss1 pdss1 coq10b coq10b coq3 coq3 LOC109523214 LOC109523214 coq5 coq5 hsd17b10 hsd17b10 ENSHCOP00000013365 ENSHCOP00000013365 coq7 coq7 LOC109517385 LOC109517385 tpi1 tpi1 LOC109510853 LOC109510853 srd5a1 srd5a1 LOC109520684 LOC109520684 LOC109509438 LOC109509438
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LOC109510228Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (315 aa)
vkorc1l1Vitamin K epoxide reductase complex, subunit 1-like 1. (175 aa)
park7Parkinson protein 7. (234 aa)
GLO1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (305 aa)
LOC109520617Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (460 aa)
coq6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (482 aa)
ndufa9NADH:ubiquinone oxidoreductase subunit A9a. (382 aa)
CBR1Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (275 aa)
coq9Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (321 aa)
kynuKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (463 aa)
LOC109513382Coenzyme Q10A. (249 aa)
LOC109528900Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (181 aa)
ENSHCOP00000021915G_PROTEIN_RECEP_F1_2 domain-containing protein. (144 aa)
ENSHCOP00000022354Uncharacterized protein. (89 aa)
aadatAminoadipate aminotransferase. (420 aa)
LOC109523501Cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4; Belongs to the cytochrome P450 family. (509 aa)
tdo2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)
kyat3Kynurenine aminotransferase 3. (415 aa)
coq24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (372 aa)
aldh8a1Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family. (490 aa)
LOC109513814Si:ch73-141c7.1. (234 aa)
hsd11b2Hydroxysteroid (11-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (423 aa)
nqo1Flavodoxin_2 domain-containing protein. (310 aa)
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (471 aa)
got2Aspartate aminotransferase. (428 aa)
coq4Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (261 aa)
kdsr3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (359 aa)
LOC109524363G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (412 aa)
ENSHCOP00000001884Si:ch73-71c20.5. (183 aa)
kyat1Kynurenine aminotransferase 1. (448 aa)
sirt6Sirtuin 6. (347 aa)
LOC109516617Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (484 aa)
afmidArylformamidase. (293 aa)
glod4Glyoxalase domain containing 4. (314 aa)
haghHydroxyacylglutathione hydrolase. (309 aa)
LOC109525131Indoleamine 2,3-dioxygenase 1. (413 aa)
ubiad1UbiA prenyltransferase domain containing 1. (351 aa)
LOC109523335PNKD metallo-beta-lactamase domain containing. (358 aa)
LOC109524007Vitamin K epoxide reductase complex, subunit 1. (167 aa)
cryzl1Crystallin, zeta (quinone reductase)-like 1. (303 aa)
gatd1Glutamine amidotransferase like class 1 domain containing 1. (213 aa)
pdss2Prenyl (decaprenyl) diphosphate synthase, subunit 2; Belongs to the FPP/GGPP synthase family. (379 aa)
srd5a23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (267 aa)
pdss1Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family. (400 aa)
coq10bCoenzyme Q10B. (245 aa)
coq3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (344 aa)
LOC109523214Cytochrome P450, family 17, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (505 aa)
coq52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (327 aa)
hsd17b10Hydroxysteroid (17-beta) dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
ENSHCOP00000013365Hydroxyacylglutathione hydrolase. (121 aa)
coq75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (220 aa)
LOC109517385Coenzyme Q8A, genome duplicate b. (567 aa)
tpi1Triosephosphate isomerase. (247 aa)
LOC109510853Coenzyme Q8B. (633 aa)
srd5a13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (264 aa)
LOC109520684Hydroxysteroid (17-beta) dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (323 aa)
LOC109509438Coenzyme Q8A, genome duplicate a. (642 aa)
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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