91 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CLSPN	Claspin. (1144 aa)
	pidd1	P53-induced death domain protein 1. (855 aa)
	ercc6	Excision repair cross-complementation group 6. (1377 aa)
	chek1	Checkpoint kinase 1; Belongs to the protein kinase superfamily. (462 aa)
	ENSHCOP00000027148	RWD domain-containing protein. (198 aa)
	casp2	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (458 aa)
	foxm1	Forkhead box M1. (642 aa)
	ENSHCOP00000026411	Uncharacterized protein. (408 aa)
	nop53	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (478 aa)
	prpf19	Pre-mRNA processing factor 19. (505 aa)
	mus81	MUS81 structure-specific endonuclease subunit. (381 aa)
	Atr	Uncharacterized protein. (106 aa)
	myo6	Myosin VIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1251 aa)
	abraxas1	Abraxas 1, BRCA1 A complex subunit. (351 aa)
	rad1	RAD1 homolog (S. pombe). (279 aa)
	blm	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (966 aa)
	babam2	BRISC and BRCA1 A complex member 2. (366 aa)
	ENSHCOP00000023012	Uncharacterized protein. (1155 aa)
	fbxo31	F-box protein 31. (538 aa)
	cdca7l	Cell division cycle associated 7b. (396 aa)
	Brcc3	BRCA1/BRCA2-containing complex, subunit 3. (284 aa)
	e2f7	E2F transcription factor 7. (662 aa)
	LOC109532531	Transcription factor AP-4 (activating enhancer binding protein 4). (317 aa)
	ENSHCOP00000021185	Basic leucine zipper transcription factor, ATF-like. (119 aa)
	tp53bp1	Tumor protein p53 binding protein, 1. (1495 aa)
	mfsd11	Uncharacterized protein. (405 aa)
	atrx	ATRX chromatin remodeler. (1645 aa)
	tipin	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (281 aa)
	LOC109521383	Fizzy/cell division cycle 20 related 1b. (481 aa)
	LOC109521384	Fizzy/cell division cycle 20 related 1b. (481 aa)
	e2f1	E2F transcription factor 1. (428 aa)
	EME2	ERCC4 domain-containing protein. (409 aa)
	LOC109518467	Zgc:112083. (501 aa)
	LOC109517197	TAO kinase 3b. (439 aa)
	LOC109518452	TAO kinase 1a. (1025 aa)
	FZR1	Fizzy/cell division cycle 20 related 1a. (495 aa)
	dot1l	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1540 aa)
	taok3	TAO kinase 3a. (885 aa)
	chek2	Checkpoint kinase 2. (518 aa)
	brca1	Uncharacterized protein. (1141 aa)
	ENSHCOP00000015947	Checkpoint suppressor 1. (225 aa)
	LOC109508147	Checkpoint suppressor 1. (398 aa)
	ZNF830	Zinc finger protein 830. (344 aa)
	nbn	Nibrin. (832 aa)
	xpc	Xeroderma pigmentosum, complementation group C. (859 aa)
	ENSHCOP00000005103	Uncharacterized protein. (167 aa)
	casp9	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (477 aa)
	mre11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (738 aa)
	LOC109527038	ATPase family AAA domain containing 5a. (1619 aa)
	Rad9b	Uncharacterized protein. (173 aa)
	dtl	Denticleless E3 ubiquitin protein ligase homolog (Drosophila). (616 aa)
	fancd2	FA complementation group D2. (1328 aa)
	cdk5rap3	CDK5 regulatory subunit associated protein 3. (501 aa)
	TFAP4	BHLH domain-containing protein. (323 aa)
	rps6ka6	Non-specific serine/threonine protein kinase. (715 aa)
	usp10	Ubiquitin carboxyl-terminal hydrolase. (871 aa)
	DONSON	Downstream neighbor of SON. (568 aa)
	mad2l2	Mitotic arrest deficient 2 like 2. (210 aa)
	topbp1	DNA topoisomerase II binding protein 1. (1350 aa)
	LOC109520609	WW domain-containing protein. (520 aa)
	hinfp	Histone H4 transcription factor. (484 aa)
	LOC109513825	Major facilitator superfamily domain containing 11. (441 aa)
	ENSHCOP00000000931	Protein kinase domain-containing protein. (480 aa)
	LOC109513794	TAO kinase 2a. (1106 aa)
	rad17	RAD17 checkpoint clamp loader component. (570 aa)
	EIF2AK4	Eukaryotic translation initiation factor 2 alpha kinase 4. (1478 aa)
	acer2	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (277 aa)
	ENSHCOP00000014556	Uncharacterized protein. (241 aa)
	ENSHCOP00000014432	Protein kinase domain-containing protein. (118 aa)
	ENSHCOP00000014406	TAO kinase 2b. (457 aa)
	wac	WW domain containing adaptor with coiled-coil a. (546 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (946 aa)
	atrip	Uncharacterized protein. (764 aa)
	LOC109532340	CEP63 domain-containing protein. (505 aa)
	hus1	Checkpoint protein; Belongs to the HUS1 family. (285 aa)
	ENSHCOP00000010512	Uncharacterized protein. (148 aa)
	Atm	TAN domain-containing protein. (311 aa)
	ENSHCOP00000009180	Uncharacterized protein. (169 aa)
	prkdc	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3890 aa)
	map3k20	Uncharacterized protein. (788 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (382 aa)
	rint1	RAD50 interactor 1. (791 aa)
	cdk1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa)
	rfwd3	Ring finger and WD repeat domain 3. (697 aa)
	ENSHCOP00000006866	Uncharacterized protein. (1585 aa)
	LOC109524819	Myosin VIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1300 aa)
	LOC109528877	Protein kinase domain-containing protein. (917 aa)
	LOC109516890	WD_REPEATS_REGION domain-containing protein. (488 aa)
	LOC109518522	Ribosomal protein S6 kinase, polypeptide 3b. (674 aa)
	ppm1d	Protein phosphatase, Mg2+/Mn2+ dependent, 1Db. (560 aa)
	babam1	BRISC and BRCA1 A complex member 1. (373 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atm	Atr	ENSHCOP00000009193	ENSHCOP00000025135	TAN domain-containing protein.	Uncharacterized protein.	0.997
Atm	Brcc3	ENSHCOP00000009193	ENSHCOP00000022578	TAN domain-containing protein.	BRCA1/BRCA2-containing complex, subunit 3.	0.641
Atm	CLSPN	ENSHCOP00000009193	ENSHCOP00000002581	TAN domain-containing protein.	Claspin.	0.579
Atm	EME2	ENSHCOP00000009193	ENSHCOP00000018644	TAN domain-containing protein.	ERCC4 domain-containing protein.	0.422
Atm	ENSHCOP00000005103	ENSHCOP00000009193	ENSHCOP00000005103	TAN domain-containing protein.	Uncharacterized protein.	0.507
Atm	ENSHCOP00000009180	ENSHCOP00000009193	ENSHCOP00000009180	TAN domain-containing protein.	Uncharacterized protein.	0.929
Atm	ENSHCOP00000014556	ENSHCOP00000009193	ENSHCOP00000014556	TAN domain-containing protein.	Uncharacterized protein.	0.598
Atm	ENSHCOP00000023012	ENSHCOP00000009193	ENSHCOP00000023012	TAN domain-containing protein.	Uncharacterized protein.	0.887
Atm	ENSHCOP00000026411	ENSHCOP00000009193	ENSHCOP00000026411	TAN domain-containing protein.	Uncharacterized protein.	0.506
Atm	LOC109527038	ENSHCOP00000009193	ENSHCOP00000004580	TAN domain-containing protein.	ATPase family AAA domain containing 5a.	0.506
Atm	Rad9b	ENSHCOP00000009193	ENSHCOP00000004340	TAN domain-containing protein.	Uncharacterized protein.	0.839
Atm	atrip	ENSHCOP00000009193	ENSHCOP00000011588	TAN domain-containing protein.	Uncharacterized protein.	0.880
Atm	atrx	ENSHCOP00000009193	ENSHCOP00000019999	TAN domain-containing protein.	ATRX chromatin remodeler.	0.507
Atm	babam1	ENSHCOP00000009193	ENSHCOP00000005805	TAN domain-containing protein.	BRISC and BRCA1 A complex member 1.	0.630
Atm	babam2	ENSHCOP00000009193	ENSHCOP00000023074	TAN domain-containing protein.	BRISC and BRCA1 A complex member 2.	0.683
Atm	blm	ENSHCOP00000009193	ENSHCOP00000023146	TAN domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.909
Atm	brca1	ENSHCOP00000009193	ENSHCOP00000016663	TAN domain-containing protein.	Uncharacterized protein.	0.968
Atm	cdca7l	ENSHCOP00000009193	ENSHCOP00000022768	TAN domain-containing protein.	Cell division cycle associated 7b.	0.717
Atm	cdk1	ENSHCOP00000009193	ENSHCOP00000007148	TAN domain-containing protein.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.580
Atm	chek1	ENSHCOP00000009193	ENSHCOP00000027175	TAN domain-containing protein.	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	0.982