STRINGSTRING
hmgcr hmgcr ENSHCOP00000004478 ENSHCOP00000004478 dusp10 dusp10 sh2b3 sh2b3 trib2 trib2 ENSHCOP00000002881 ENSHCOP00000002881 fgf2 fgf2 cdk5rap3 cdk5rap3 ENSHCOP00000002689 ENSHCOP00000002689 tnfsf11 tnfsf11 LOC109511462 LOC109511462 tenm1 tenm1 ENSHCOP00000002364 ENSHCOP00000002364 LOC109527850 LOC109527850 sash1 sash1 LOC109511384 LOC109511384 LOC109508512 LOC109508512 LOC109528066 LOC109528066 LOC109529256 LOC109529256 LOC109510241 LOC109510241 LOC109517399 LOC109517399 spry4 spry4 LOC109518807 LOC109518807 LOC109521511 LOC109521511 map3k4 map3k4 LOC109531588 LOC109531588 LOC109513534 LOC109513534 LOC109512876 LOC109512876 il34 il34 DRD4 DRD4 Pik3cg Pik3cg LOC109530358 LOC109530358 LOC109509080 LOC109509080 map2k5 map2k5 PIK3R5 PIK3R5 LOC109530503 LOC109530503 hgs hgs LOC109513761 LOC109513761 ENSHCOP00000020575 ENSHCOP00000020575 LOC109514277 LOC109514277 LOC109515764 LOC109515764 aida aida ENSHCOP00000019437 ENSHCOP00000019437 LOC109508087 LOC109508087 LOC109517731 LOC109517731 ENSHCOP00000018323 ENSHCOP00000018323 bmp4 bmp4 fzd8 fzd8 dusp19 dusp19 map2k7 map2k7 map3k7 map3k7 smpd1 smpd1 pik3r5 pik3r5 LOC109510758 LOC109510758 tgfa tgfa map3k13 map3k13 LOC109517234 LOC109517234 ENSHCOP00000013347 ENSHCOP00000013347 ENSHCOP00000013336 ENSHCOP00000013336 ern1 ern1 LOC109517974 LOC109517974 LOC109513432 LOC109513432 fzd4 fzd4 sorl1 sorl1 NOX4 NOX4 LOC109525531 LOC109525531 LOC109511602 LOC109511602 ENSHCOP00000010147 ENSHCOP00000010147 nf1 nf1 LOC109525561 LOC109525561 LOC109528765 LOC109528765 tnfrsf11a tnfrsf11a lime1 lime1 LOC109518923 LOC109518923 htr2b htr2b ENSHCOP00000008554 ENSHCOP00000008554 ajuba ajuba ENSHCOP00000007650 ENSHCOP00000007650 SPRY3 SPRY3 tsg101 tsg101 paqr3 paqr3 pdgfc pdgfc ENSHCOP00000007014 ENSHCOP00000007014 ENSHCOP00000006996 ENSHCOP00000006996 ENSHCOP00000006922 ENSHCOP00000006922 LOC109511398 LOC109511398 LOC109513557 LOC109513557 LOC109531655 LOC109531655 LOC109531653 LOC109531653 ptprc ptprc gba gba LOC109526430 LOC109526430 sfrp2 sfrp2 axin1 axin1 LOC109527308 LOC109527308
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hmgcr3-hydroxy-3-methylglutaryl coenzyme A reductase. (887 aa)
ENSHCOP00000004478NIMA-related kinase 10. (746 aa)
dusp10Dual specificity phosphatase 10. (472 aa)
sh2b3SH2B adaptor protein 3. (671 aa)
trib2Tribbles pseudokinase 2. (337 aa)
ENSHCOP00000002881Sprouty homolog 1, antagonist of FGF signaling (Drosophila). (314 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (159 aa)
cdk5rap3CDK5 regulatory subunit associated protein 3. (501 aa)
ENSHCOP00000002689Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa)
tnfsf11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (266 aa)
LOC109511462Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (471 aa)
tenm1Uncharacterized protein. (2641 aa)
ENSHCOP00000002364Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (206 aa)
LOC109527850Tpd52 like 1. (203 aa)
sash1SAM and SH3 domain containing 1a. (1177 aa)
LOC109511384Endoplasmic reticulum to nucleus signaling 2. (920 aa)
LOC109508512Si:dkey-175m17.7. (863 aa)
LOC109528066Dystrobrevin binding protein 1b. (192 aa)
LOC109529256Protein kinase domain-containing protein. (503 aa)
LOC109510241Angiotensinogen; Belongs to the serpin family. (459 aa)
LOC109517399Programmed cell death 10b. (210 aa)
spry4Sprouty homolog 4 (Drosophila). (370 aa)
LOC109518807Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (205 aa)
LOC109521511Protein kinase domain-containing protein. (358 aa)
map3k4Mitogen-activated protein kinase kinase kinase 4. (1500 aa)
LOC109531588Tribbles pseudokinase 1. (325 aa)
LOC109513534Uncharacterized protein. (259 aa)
LOC109512876Programmed cell death 10a. (206 aa)
il34Interleukin 34. (200 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (399 aa)
Pik3cgPI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (262 aa)
LOC109530358Zgc:123278. (192 aa)
LOC109509080TGF_BETA_2 domain-containing protein. (247 aa)
map2k5Mitogen-activated protein kinase kinase 5. (409 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (655 aa)
LOC109530503Protein tyrosine phosphatase non-receptor type 5. (386 aa)
hgsHepatocyte growth factor-regulated tyrosine kinase substrate. (795 aa)
LOC109513761Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
ENSHCOP00000020575PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (216 aa)
LOC109514277G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (374 aa)
LOC109515764Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins [...] (163 aa)
aidaAxin interactor, dorsalization associated. (306 aa)
ENSHCOP00000019437Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (143 aa)
LOC109508087Progestin and adipoQ receptor family member IIIb. (307 aa)
LOC109517731Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (242 aa)
ENSHCOP00000018323PKD domain-containing protein. (237 aa)
bmp4Bone morphogenetic protein 4. (350 aa)
fzd8Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
dusp19Dual specificity phosphatase 19b. (193 aa)
map2k7Mitogen-activated protein kinase kinase 7. (422 aa)
map3k7Mitogen-activated protein kinase kinase kinase 7. (568 aa)
smpd1Sphingomyelin phosphodiesterase 1, acid lysosomal. (510 aa)
pik3r5Phosphoinositide-3-kinase, regulatory subunit 5. (786 aa)
LOC109510758Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
tgfaTransforming growth factor, alpha. (244 aa)
map3k13Mitogen-activated protein kinase kinase kinase. (990 aa)
LOC109517234Uncharacterized protein. (775 aa)
ENSHCOP00000013347Uncharacterized protein. (1158 aa)
ENSHCOP00000013336Protein kinase domain-containing protein. (472 aa)
ern1Endoplasmic reticulum to nucleus signaling 1. (1053 aa)
LOC109517974Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (173 aa)
LOC109513432Interleukin-1. (238 aa)
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (531 aa)
sorl1Sortilin-related receptor, L(DLR class) A repeats containing. (2130 aa)
NOX4NADPH oxidase 4. (499 aa)
LOC109525531Uncharacterized protein. (324 aa)
LOC109511602Fibroblast growth factor receptor. (691 aa)
ENSHCOP00000010147Endothelin 1. (182 aa)
nf1Neurofibromin 1b. (2754 aa)
LOC1095255613-hydroxy-3-methylglutaryl coenzyme A reductase. (876 aa)
LOC109528765Dickkopf WNT signaling pathway inhibitor 1a. (249 aa)
tnfrsf11aTumor necrosis factor receptor superfamily, member 11a, NFKB activator. (595 aa)
lime1Uncharacterized protein. (531 aa)
LOC109518923Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (590 aa)
htr2b5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (470 aa)
ENSHCOP00000008554Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (234 aa)
ajubaAjuba LIM protein. (640 aa)
ENSHCOP00000007650Sprouty RTK signaling antagonist 2. (283 aa)
SPRY3Sprouty RTK signaling antagonist 3. (283 aa)
tsg101Tumor susceptibility 101a. (390 aa)
paqr3Progestin and adipoQ receptor family member IIIa. (345 aa)
pdgfcPlatelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (326 aa)
ENSHCOP00000007014Interleukin-1 receptor-associated kinase 3. (331 aa)
ENSHCOP00000006996Uncharacterized protein. (113 aa)
ENSHCOP00000006922SCY domain-containing protein. (117 aa)
LOC109511398Uncharacterized protein. (887 aa)
LOC109513557CD40 molecule, TNF receptor superfamily member 5. (309 aa)
LOC109531655Apolipoprotein Eb. (297 aa)
LOC109531653Uncharacterized protein. (270 aa)
ptprcProtein tyrosine phosphatase receptor type C. (1232 aa)
gbaGlucosylceramidase. (525 aa)
LOC109526430Bone morphogenetic protein 16. (439 aa)
sfrp2Secreted frizzled-related protein 2. (299 aa)
axin1Axin 1. (786 aa)
LOC109527308Epithelial mitogen homolog (mouse). (141 aa)
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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