22 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Msc	Musculin (activated B-cell factor-1). (120 aa)
	hlx	H2.0-like homeo box 1 (Drosophila). (369 aa)
	invs	Inversin. (669 aa)
	hnf1b	HNF1 homeobox Ba. (629 aa)
	nkx2-3	NK2 homeobox 3. (338 aa)
	mib1	Mindbomb E3 ubiquitin protein ligase 1. (995 aa)
	LOC109525531	Uncharacterized protein. (324 aa)
	tp63	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (544 aa)
	VANGL2	Vang-like protein. (527 aa)
	ENSHCOP00000009146	Abelson helper integration site 1. (838 aa)
	NKX2-3	NK2 homeobox 3. (273 aa)
	tcf21	Transcription factor 21. (159 aa)
	sfrp2	Secreted frizzled-related protein 2. (299 aa)
	tbx20	T-box transcription factor 20. (444 aa)
	LOC109519656	Uncharacterized protein. (661 aa)
	ENSHCOP00000002506	BCL2 apoptosis regulator b. (225 aa)
	ENSHCOP00000002481	BCL2 apoptosis regulator b. (221 aa)
	prkci	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	wtip	WT1 interacting protein. (633 aa)
	tp73	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (571 aa)
	ENSHCOP00000023388	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (407 aa)
	utp25	UTP25 small subunit processor component. (753 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000009146	invs	ENSHCOP00000009146	ENSHCOP00000019162	Abelson helper integration site 1.	Inversin.	0.640
LOC109525531	VANGL2	ENSHCOP00000011682	ENSHCOP00000010661	Uncharacterized protein.	Vang-like protein.	0.451
VANGL2	LOC109525531	ENSHCOP00000010661	ENSHCOP00000011682	Vang-like protein.	Uncharacterized protein.	0.451
VANGL2	invs	ENSHCOP00000010661	ENSHCOP00000019162	Vang-like protein.	Inversin.	0.507
VANGL2	sfrp2	ENSHCOP00000010661	ENSHCOP00000005098	Vang-like protein.	Secreted frizzled-related protein 2.	0.451
invs	ENSHCOP00000009146	ENSHCOP00000019162	ENSHCOP00000009146	Inversin.	Abelson helper integration site 1.	0.640
invs	VANGL2	ENSHCOP00000019162	ENSHCOP00000010661	Inversin.	Vang-like protein.	0.507
sfrp2	VANGL2	ENSHCOP00000005098	ENSHCOP00000010661	Secreted frizzled-related protein 2.	Vang-like protein.	0.451