STRINGSTRING
stk11 stk11 AQP11 AQP11 llgl2 llgl2 LOC109509080 LOC109509080 map2k5 map2k5 igf2 igf2 sulf1 sulf1 il10 il10 LOC109529028 LOC109529028 LOC109531720 LOC109531720 ENSHCOP00000020575 ENSHCOP00000020575 ENSHCOP00000020347 ENSHCOP00000020347 ENSHCOP00000020337 ENSHCOP00000020337 ENSHCOP00000020324 ENSHCOP00000020324 rreb1 rreb1 rb1 rb1 LOC109515764 LOC109515764 LOC109527064 LOC109527064 hlx hlx LOC109511132 LOC109511132 ENSHCOP00000019306 ENSHCOP00000019306 ENSHCOP00000019285 ENSHCOP00000019285 aimp1 aimp1 LOC109531196 LOC109531196 rgcc rgcc LOC109511366 LOC109511366 vip vip LOC109529845 LOC109529845 id1 id1 LOC109520436 LOC109520436 LOC109519162 LOC109519162 vegfc vegfc bmp4 bmp4 LOC109511954 LOC109511954 flcn flcn LOC109520606 LOC109520606 LOC109506885 LOC109506885 ENSHCOP00000016441 ENSHCOP00000016441 ENSHCOP00000016179 ENSHCOP00000016179 LOC109531321 LOC109531321 LOC109510758 LOC109510758 nkx2-3 nkx2-3 ENSHCOP00000014775 ENSHCOP00000014775 LOC109532403 LOC109532403 pdx1 pdx1 LOC109525219 LOC109525219 tgfa tgfa tnmd tnmd CASK CASK hmx2 hmx2 LOC109528097 LOC109528097 ywhaq ywhaq LOC109517974 LOC109517974 fa2h fa2h LOC109511660 LOC109511660 VASH1 VASH1 LOC109525531 LOC109525531 bad bad bmpr2 bmpr2 pex2 pex2 ENSHCOP00000010248 ENSHCOP00000010248 ENSHCOP00000010133 ENSHCOP00000010133 ift52 ift52 nf1 nf1 vash2 vash2 vegfa vegfa agtr1 agtr1 aggf1 aggf1 LOC109520909 LOC109520909 C5AR1 C5AR1 htr2b htr2b LOC109521474 LOC109521474 LOC109516804 LOC109516804 ENSHCOP00000008341 ENSHCOP00000008341 ENSHCOP00000008218 ENSHCOP00000008218 phox2b phox2b Tbc1d31 Tbc1d31 ENSHCOP00000007892 ENSHCOP00000007892 wdr13 wdr13 hpn hpn LOC109508904 LOC109508904 ENSHCOP00000007590 ENSHCOP00000007590 LOC109527673 LOC109527673 mydgf mydgf NKX2-3 NKX2-3 ppard ppard LOC109531655 LOC109531655 LOC109531653 LOC109531653 WNT2B WNT2B AR AR LOC109526430 LOC109526430 sfrp2 sfrp2 LOC109527308 LOC109527308 LOC109525693 LOC109525693 dusp10 dusp10 LOC109522206 LOC109522206 wdr77 wdr77 st8sia1 st8sia1 cdkn1b cdkn1b LOC109523155 LOC109523155 GATA2 GATA2 ift80 ift80 cdc73 cdc73 fgf2 fgf2 prok1 prok1 ENSHCOP00000002650 ENSHCOP00000002650 nkx2-5 nkx2-5 LOC109524475 LOC109524475 LOC109511462 LOC109511462 sulf2 sulf2 CNMD CNMD dab2 dab2 il12b il12b LOC109514566 LOC109514566 LOC109514626 LOC109514626 tnfaip3 tnfaip3 LOC109524623 LOC109524623 ENSHCOP00000001163 ENSHCOP00000001163 nupr1 nupr1 fgf7 fgf7 Atpif1 Atpif1 sirt6 sirt6 myc myc sp1 sp1 LOC109510605 LOC109510605 LOC109521925 LOC109521925 tgfb2 tgfb2 ENSHCOP00000022214 ENSHCOP00000022214 tinf2 tinf2 deaf1 deaf1 ENSHCOP00000023012 ENSHCOP00000023012 LOC109524148 LOC109524148 LOC109513534 LOC109513534 LOC109524113 LOC109524113 rptor rptor LOC109516568 LOC109516568 ENSHCOP00000024721 ENSHCOP00000024721 smo smo xbp1 xbp1 scg2 scg2 LOC109522629 LOC109522629 sav1 sav1 LOC109509807 LOC109509807 bax bax ENSHCOP00000026803 ENSHCOP00000026803 STXBP4 STXBP4 APOH APOH ENSHCOP00000027596 ENSHCOP00000027596 LOC109523357 LOC109523357 LOC109508512 LOC109508512 Vegfb Vegfb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (430 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
llgl2LLGL scribble cell polarity complex component 2. (949 aa)
LOC109509080TGF_BETA_2 domain-containing protein. (247 aa)
map2k5Mitogen-activated protein kinase kinase 5. (409 aa)
igf2Insulin-like growth factor 2b. (216 aa)
sulf1Extracellular sulfatase. (880 aa)
il10Uncharacterized protein. (236 aa)
LOC109529028Uncharacterized protein. (499 aa)
LOC109531720ADAM metallopeptidase domain 17b. (805 aa)
ENSHCOP00000020575PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (216 aa)
ENSHCOP00000020347Apelin receptor early endogenous ligand. (62 aa)
ENSHCOP00000020337G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (367 aa)
ENSHCOP00000020324G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (344 aa)
rreb1Ras responsive element binding protein 1a. (1447 aa)
rb1Retinoblastoma 1. (903 aa)
LOC109515764Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins [...] (163 aa)
LOC109527064ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (495 aa)
hlxH2.0-like homeo box 1 (Drosophila). (369 aa)
LOC109511132tRNA-binding domain-containing protein. (314 aa)
ENSHCOP00000019306Sirtuin 1. (369 aa)
ENSHCOP00000019285Deacetylase sirtuin-type domain-containing protein. (166 aa)
aimp1Aminoacyl tRNA synthetase complex interacting multifunctional protein 1a. (316 aa)
LOC109531196Chondromodulin. (293 aa)
rgccRegulator of cell cycle. (130 aa)
LOC109511366Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (125 aa)
vipVasoactive intestinal peptide. (152 aa)
LOC109529845Cyclin-dependent kinase inhibitor 1Cb. (202 aa)
id1Inhibitor of DNA binding 1, HLH protein. (132 aa)
LOC109520436ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (526 aa)
LOC109519162ELL associated factor 2. (275 aa)
vegfcVascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family. (393 aa)
bmp4Bone morphogenetic protein 4. (350 aa)
LOC109511954Transforming growth factor beta; Belongs to the TGF-beta family. (423 aa)
flcnFolliculin. (550 aa)
LOC109520606Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
LOC109506885Secretogranin II (chromogranin C), b. (590 aa)
ENSHCOP00000016441ERBB receptor feedback inhibitor 1a. (275 aa)
ENSHCOP00000016179EMI domain-containing protein. (828 aa)
LOC109531321Nuclear receptor subfamily 1, group D, member 4a. (571 aa)
LOC109510758Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
nkx2-3NK2 homeobox 3. (338 aa)
ENSHCOP00000014775Insulin-like growth factor 1. (181 aa)
LOC109532403Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (290 aa)
pdx1Pancreatic and duodenal homeobox 1. (250 aa)
LOC109525219NK3 homeobox 1. (189 aa)
tgfaTransforming growth factor, alpha. (244 aa)
tnmdTenomodulin. (296 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (951 aa)
hmx2H6 family homeobox 2. (261 aa)
LOC109528097JunE proto-oncogene, AP-1 transcription factor subunit. (344 aa)
ywhaqADAM metallopeptidase domain 17a. (883 aa)
LOC109517974Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (173 aa)
fa2hFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (381 aa)
LOC109511660Apelin receptor a; Belongs to the G-protein coupled receptor 1 family. (376 aa)
VASH1Vasohibin 1. (335 aa)
LOC109525531Uncharacterized protein. (324 aa)
badUncharacterized protein. (173 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (492 aa)
pex2Peroxisomal biogenesis factor 2. (313 aa)
ENSHCOP00000010248Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (433 aa)
ENSHCOP00000010133Aminoacyl tRNA synthetase complex interacting multifunctional protein 1b. (315 aa)
ift52Intraflagellar transport 52 homolog (Chlamydomonas). (435 aa)
nf1Neurofibromin 1b. (2754 aa)
vash2Vasohibin 2. (363 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (174 aa)
agtr1Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family. (365 aa)
aggf1Angiogenic factor with G patch and FHA domains 1. (738 aa)
LOC109520909Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family. (885 aa)
C5AR1Complement C5a receptor 1. (325 aa)
htr2b5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (470 aa)
LOC109521474Prokineticin 2. (107 aa)
LOC109516804LRRCT domain-containing protein. (351 aa)
ENSHCOP00000008341LRRCT domain-containing protein. (319 aa)
ENSHCOP00000008218Apelin receptor b; Belongs to the G-protein coupled receptor 1 family. (359 aa)
phox2bPaired like homeobox 2Bb. (286 aa)
Tbc1d31WD_REPEATS_REGION domain-containing protein. (343 aa)
ENSHCOP00000007892Rab-GAP TBC domain-containing protein. (432 aa)
wdr13WD repeat domain 13. (482 aa)
hpnHepsin; Belongs to the peptidase S1 family. (426 aa)
LOC109508904Uncharacterized protein. (146 aa)
ENSHCOP00000007590Fibroblast growth factor binding protein 1b. (204 aa)
LOC109527673GRANULINS domain-containing protein. (188 aa)
mydgfMyeloid-derived growth factor. (170 aa)
NKX2-3NK2 homeobox 3. (273 aa)
ppardPeroxisome proliferator-activated receptor delta b. (375 aa)
LOC109531655Apolipoprotein Eb. (297 aa)
LOC109531653Uncharacterized protein. (270 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
ARAndrogen receptor. (703 aa)
LOC109526430Bone morphogenetic protein 16. (439 aa)
sfrp2Secreted frizzled-related protein 2. (299 aa)
LOC109527308Epithelial mitogen homolog (mouse). (141 aa)
LOC109525693Keratinocyte differentiation factor 1a. (361 aa)
dusp10Dual specificity phosphatase 10. (472 aa)
LOC109522206Cyclin-dependent kinase inhibitor 1A. (165 aa)
wdr77WD_REPEATS_REGION domain-containing protein. (326 aa)
st8sia1ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (331 aa)
cdkn1bCyclin-dependent kinase inhibitor 1Bb. (179 aa)
LOC109523155Sirtuin 1. (657 aa)
GATA2GATA binding protein 2. (434 aa)
ift80Intraflagellar transport 80 homolog (Chlamydomonas). (778 aa)
cdc73Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (547 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (159 aa)
prok1Prokineticin 1. (107 aa)
ENSHCOP00000002650PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (187 aa)
nkx2-5NK2 homeobox 5. (314 aa)
LOC109524475Uncharacterized protein. (661 aa)
LOC109511462Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (471 aa)
sulf2Extracellular sulfatase. (872 aa)
CNMDChondromodulin. (315 aa)
dab2DAB adaptor protein 2. (741 aa)
il12bInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (355 aa)
LOC109514566Pygopus homolog 2 (Drosophila). (585 aa)
LOC109514626Extracellular matrix protein 1a. (139 aa)
tnfaip3Tumor necrosis factor, alpha-induced protein 3. (753 aa)
LOC109524623LIM domain-containing protein. (335 aa)
ENSHCOP00000001163G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (337 aa)
nupr1Nuclear protein 1b. (74 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa)
Atpif1Uncharacterized protein. (75 aa)
sirt6Sirtuin 6. (347 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (433 aa)
sp1Sp1 transcription factor. (523 aa)
LOC109510605Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
LOC109521925Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family. (179 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
ENSHCOP00000022214LIM zinc-binding domain-containing protein. (58 aa)
tinf2TERF1 (TRF1)-interacting nuclear factor 2. (590 aa)
deaf1DEAF1 transcription factor. (538 aa)
ENSHCOP00000023012Uncharacterized protein. (1155 aa)
LOC109524148Uncharacterized protein. (284 aa)
LOC109513534Uncharacterized protein. (259 aa)
LOC109524113Uncharacterized protein. (1303 aa)
rptorRegulatory associated protein of MTOR, complex 1. (1265 aa)
LOC109516568Baculoviral IAP repeat containing 5a. (137 aa)
ENSHCOP00000024721Intraflagellar transport 74. (544 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (808 aa)
xbp1X-box binding protein 1. (262 aa)
scg2Uncharacterized protein. (598 aa)
LOC109522629GATA binding protein 2a. (477 aa)
sav1Salvador family WW domain containing protein 1. (403 aa)
LOC109509807Fibroblast growth factor binding protein 1b. (204 aa)
baxBCL2 associated X, apoptosis regulator a. (255 aa)
ENSHCOP00000026803Granulin b. (551 aa)
STXBP4Syntaxin binding protein 4. (390 aa)
APOHApolipoprotein H. (350 aa)
ENSHCOP00000027596Noggin; Belongs to the noggin family. (222 aa)
LOC109523357LIM domain-containing protein. (403 aa)
LOC109508512Si:dkey-175m17.7. (863 aa)
VegfbPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (119 aa)
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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