(48 nodes) Regulation of dendrite development network (Hippocampus comes)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	stk11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (430 aa)
	dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (966 aa)
	il1rapl2	Interleukin 1 receptor accessory protein-like 2. (674 aa)
	gsk3b	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (421 aa)
	cux2	Homeobox protein cut-like. (1323 aa)
	LOC109518393	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (439 aa)
	anapc2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (745 aa)
	CRTC1	CREB regulated transcription coactivator 1b. (564 aa)
	ENSHCOP00000007103	Ankyrin repeat domain 27 (VPS9 domain). (380 aa)
	fat3	FAT atypical cadherin 3a. (4524 aa)
	CRK	CRK proto-oncogene, adaptor protein. (316 aa)
	nedd4l	NEDD4 like E3 ubiquitin protein ligase. (1260 aa)
	LOC109531651	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
	LOC109524107	Nuclear factor of activated T cells 4. (805 aa)
	hecw1	Si:ch211-188f17.1. (1319 aa)
	ENSHCOP00000013481	Reelin domain-containing protein. (267 aa)
	caprin1	Cell cycle associated protein 1b. (693 aa)
	LOC109525343	Leucine zipper, putative tumor suppressor 1. (530 aa)
	ENSHCOP00000013939	HECT domain-containing protein. (203 aa)
	ENSHCOP00000015325	IMD domain-containing protein. (151 aa)
	LOC109530718	Si:dkey-40c11.2. (621 aa)
	dbnl	Drebrin-like b. (475 aa)
	id1	Inhibitor of DNA binding 1, HLH protein. (132 aa)
	LOC109530653	Interleukin 1 receptor accessory protein-like 1a. (716 aa)
	nedd4	E3 ubiquitin-protein ligase. (822 aa)
	Kndc1	Uncharacterized protein. (119 aa)
	LOC109532545	BAI1-associated protein 2a. (553 aa)
	LOC109514330	Cell cycle associated protein 1a. (632 aa)
	ENSHCOP00000021843	Uncharacterized protein. (798 aa)
	rapgef2	Rap guanine nucleotide exchange factor (GEF) 2. (1561 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (306 aa)
	pqbp1	Polyglutamine binding protein 1. (225 aa)
	LOC109516810	PKS_ER domain-containing protein. (420 aa)
	cdkl5	Protein kinase domain-containing protein. (987 aa)
	ENSHCOP00000023824	HECT domain-containing protein. (342 aa)
	ENSHCOP00000023838	C2 domain-containing protein. (331 aa)
	eef2k	Eukaryotic elongation factor 2 kinase. (737 aa)
	Caprin2	C1q domain-containing protein. (170 aa)
	LOC109518059	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (214 aa)
	Reln	Uncharacterized protein. (877 aa)
	ENSHCOP00000026026	Uncharacterized protein. (863 aa)
	ENSHCOP00000026938	Uncharacterized protein. (102 aa)
	dbn1	Drebrin 1. (482 aa)
	LOC109528733	Protein kinase C and casein kinase substrate in neurons 1a. (439 aa)
	fbxw8	F-box and WD repeat domain containing 8. (633 aa)
	LOC109521915	Cordon-bleu WH2 repeat protein. (1443 aa)
	LOC109519613	Reticulon 4 interacting protein 1. (402 aa)
	LOC109508356	Protein kinase C and casein kinase substrate in neurons 1b. (445 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRK	ENSHCOP00000015325	ENSHCOP00000007822	ENSHCOP00000015325	CRK proto-oncogene, adaptor protein.	IMD domain-containing protein.	0.498
CRK	LOC109532545	ENSHCOP00000007822	ENSHCOP00000021147	CRK proto-oncogene, adaptor protein.	BAI1-associated protein 2a.	0.498
CRK	crkl	ENSHCOP00000007822	ENSHCOP00000022046	CRK proto-oncogene, adaptor protein.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.911
Caprin2	LOC109514330	ENSHCOP00000024058	ENSHCOP00000021767	C1q domain-containing protein.	Cell cycle associated protein 1a.	0.891
Caprin2	caprin1	ENSHCOP00000024058	ENSHCOP00000013553	C1q domain-containing protein.	Cell cycle associated protein 1b.	0.897
ENSHCOP00000007103	ENSHCOP00000021843	ENSHCOP00000007103	ENSHCOP00000021843	Ankyrin repeat domain 27 (VPS9 domain).	Uncharacterized protein.	0.898
ENSHCOP00000013481	ENSHCOP00000026026	ENSHCOP00000013481	ENSHCOP00000026026	Reelin domain-containing protein.	Uncharacterized protein.	0.946
ENSHCOP00000013481	Reln	ENSHCOP00000013481	ENSHCOP00000026006	Reelin domain-containing protein.	Uncharacterized protein.	0.938
ENSHCOP00000013939	ENSHCOP00000023838	ENSHCOP00000013939	ENSHCOP00000023838	HECT domain-containing protein.	C2 domain-containing protein.	0.898
ENSHCOP00000015325	CRK	ENSHCOP00000015325	ENSHCOP00000007822	IMD domain-containing protein.	CRK proto-oncogene, adaptor protein.	0.498
ENSHCOP00000015325	crkl	ENSHCOP00000015325	ENSHCOP00000022046	IMD domain-containing protein.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.498
ENSHCOP00000021843	ENSHCOP00000007103	ENSHCOP00000021843	ENSHCOP00000007103	Uncharacterized protein.	Ankyrin repeat domain 27 (VPS9 domain).	0.898
ENSHCOP00000023824	ENSHCOP00000023838	ENSHCOP00000023824	ENSHCOP00000023838	HECT domain-containing protein.	C2 domain-containing protein.	0.899
ENSHCOP00000023838	ENSHCOP00000013939	ENSHCOP00000023838	ENSHCOP00000013939	C2 domain-containing protein.	HECT domain-containing protein.	0.898
ENSHCOP00000023838	ENSHCOP00000023824	ENSHCOP00000023838	ENSHCOP00000023824	C2 domain-containing protein.	HECT domain-containing protein.	0.899
ENSHCOP00000023838	nedd4	ENSHCOP00000023838	ENSHCOP00000019019	C2 domain-containing protein.	E3 ubiquitin-protein ligase.	0.813
ENSHCOP00000023838	nedd4l	ENSHCOP00000023838	ENSHCOP00000009067	C2 domain-containing protein.	NEDD4 like E3 ubiquitin protein ligase.	0.409
ENSHCOP00000026026	ENSHCOP00000013481	ENSHCOP00000026026	ENSHCOP00000013481	Uncharacterized protein.	Reelin domain-containing protein.	0.946
LOC109508356	LOC109521915	ENSHCOP00000000705	ENSHCOP00000000114	Protein kinase C and casein kinase substrate in neurons 1b.	Cordon-bleu WH2 repeat protein.	0.404
LOC109514330	Caprin2	ENSHCOP00000021767	ENSHCOP00000024058	Cell cycle associated protein 1a.	C1q domain-containing protein.	0.891