(120 nodes) Regulation of synapse organization network (Hippocampus comes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ctnna2	Catenin (cadherin-associated protein), alpha 2. (935 aa)
	LOC109510655	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (696 aa)
	LOC109507325	Peptidase_S9 domain-containing protein. (347 aa)
	LOC109517156	Netrin G2. (521 aa)
	LOC109514620	Ephrin-A1a; Belongs to the ephrin family. (226 aa)
	LOC109508116	Rho GTPase activating protein 22. (709 aa)
	frmpd3	FERM and PDZ domain containing 3. (1703 aa)
	LOC109511902	Dynactin 1a. (1286 aa)
	slitrk2	SLIT and NTRK-like family, member 2. (857 aa)
	dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (966 aa)
	amigo1	Adhesion molecule with Ig-like domain 1. (334 aa)
	agrn	Agrin. (2075 aa)
	LOC109531313	Toll-like receptor 7. (1176 aa)
	il1rapl2	Interleukin 1 receptor accessory protein-like 2. (674 aa)
	cdk5	Cyclin-dependent kinase 5. (258 aa)
	slc7a11	Solute carrier family 7 member 11. (493 aa)
	HOMER1	Homer scaffold protein 1. (356 aa)
	NEUROD2	Neurogenic differentiation factor. (363 aa)
	cux2	Homeobox protein cut-like. (1323 aa)
	lrrtm2	Leucine rich repeat transmembrane neuronal 2. (544 aa)
	ctnna1	Catenin (cadherin-associated protein), alpha 1. (907 aa)
	anapc2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (745 aa)
	LOC109523726	Leucine rich repeat neuronal 3b. (710 aa)
	cln3	Battenin. (425 aa)
	vps35	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (798 aa)
	LOC109522550	Ig-like domain-containing protein. (721 aa)
	ENSHCOP00000006162	Ig-like domain-containing protein. (449 aa)
	LOC109531653	Uncharacterized protein. (270 aa)
	LOC109531655	Apolipoprotein Eb. (297 aa)
	LRFN2	Leucine rich repeat and fibronectin type III domain containing 2. (788 aa)
	Mycbp2	RING-type domain-containing protein. (497 aa)
	ENSHCOP00000007133	Uncharacterized protein. (383 aa)
	ENSHCOP00000007634	Uncharacterized protein. (614 aa)
	ENSHCOP00000007872	Uncharacterized protein. (348 aa)
	LOC109532196	Abhydrolase domain containing 17A. (320 aa)
	LOC109521614	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (685 aa)
	ENSHCOP00000008307	ANK_REP_REGION domain-containing protein. (276 aa)
	ube3a	Ubiquitin protein ligase E3A. (809 aa)
	LOC109521583	Leucine rich repeat neuronal 1. (717 aa)
	LOC109515023	Peptidase S72 domain-containing protein. (880 aa)
	ENSHCOP00000008601	Ig-like domain-containing protein. (466 aa)
	flrt3	Fibronectin leucine rich transmembrane 3. (650 aa)
	LOC109528176	Uncharacterized protein. (976 aa)
	LOC109528765	Dickkopf WNT signaling pathway inhibitor 1a. (249 aa)
	SEMA4D	Semaphorin 4D; Belongs to the semaphorin family. (891 aa)
	setd5	SET domain containing 5. (1373 aa)
	LOC109524107	Nuclear factor of activated T cells 4. (805 aa)
	slitrk6	SLIT and NTRK-like family, member 6. (844 aa)
	DAG1	Dystroglycan 1. (850 aa)
	amigo3	Adhesion molecule with Ig-like domain 3. (506 aa)
	ghsr	Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family. (365 aa)
	LOC109507195	Adhesion G protein-coupled receptor L1a; Belongs to the G-protein coupled receptor 2 family. (1355 aa)
	LOC109514143	Homer scaffold protein 1b. (358 aa)
	clstn1	Calsyntenin 1. (965 aa)
	ENSHCOP00000012870	CortBP2 domain-containing protein. (644 aa)
	LOC109507473	Cerebellin 1 precursor. (187 aa)
	ENSHCOP00000013336	Protein kinase domain-containing protein. (472 aa)
	ENSHCOP00000013347	Uncharacterized protein. (1158 aa)
	ENSHCOP00000013481	Reelin domain-containing protein. (267 aa)
	clstn2	Uncharacterized protein. (943 aa)
	caprin1	Cell cycle associated protein 1b. (693 aa)
	slitrk3	SLIT and NTRK-like family, member 3a. (902 aa)
	LOC109525344	Survival of motor neuron 1, telomeric. (295 aa)
	adgrl2	Adhesion G protein-coupled receptor L2a; Belongs to the G-protein coupled receptor 2 family. (1388 aa)
	lrrtm1	Leucine rich repeat transmembrane neuronal 1. (525 aa)
	abhd17c	Abhydrolase domain containing 17C. (294 aa)
	UBE3A	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (891 aa)
	vstm5	IG domain-containing protein. (194 aa)
	ENSHCOP00000015325	IMD domain-containing protein. (151 aa)
	LOC109521300	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (1452 aa)
	LOC109525940	Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a. (1619 aa)
	ENSHCOP00000016069	Si:dkeyp-74b6.2. (106 aa)
	ARHGAP22	Rho GTPase activating protein 22. (607 aa)
	LOC109530718	Si:dkey-40c11.2. (621 aa)
	LOC109522341	Uncharacterized protein. (715 aa)
	ENSHCOP00000017013	Uncharacterized protein. (430 aa)
	LOC109519479	Abl-interactor 2a. (463 aa)
	TANC2	Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2. (2122 aa)
	dbnl	Drebrin-like b. (475 aa)
	LOC109527145	Calsyntenin 2. (920 aa)
	dlg5	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (1860 aa)
	gripap1	GRIP1 associated protein 1. (874 aa)
	ENSHCOP00000018552	LRRCT domain-containing protein. (246 aa)
	LOC109530653	Interleukin 1 receptor accessory protein-like 1a. (716 aa)
	ENSHCOP00000019697	Ig-like domain-containing protein. (504 aa)
	Colq	Collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase. (258 aa)
	MUSK	Muscle associated receptor tyrosine kinase. (859 aa)
	ENSHCOP00000020626	Leucine rich repeat neuronal 3b. (325 aa)
	adnp	Activity-dependent neuroprotector homeobox b. (1032 aa)
	LOC109532545	BAI1-associated protein 2a. (553 aa)
	LOC109521090	Ephrin-A1b; Belongs to the ephrin family. (233 aa)
	LOC109514330	Cell cycle associated protein 1a. (632 aa)
	ENSHCOP00000022280	Leucine rich repeat and fibronectin type III domain containing 4b. (398 aa)
	ephb3	Uncharacterized protein. (985 aa)
	lrfn5	Leucine rich repeat and fibronectin type III domain containing 5a. (545 aa)
	LOC109513534	Uncharacterized protein. (259 aa)
	cdkl5	Protein kinase domain-containing protein. (987 aa)
	nectin1	Nectin cell adhesion molecule 1b. (537 aa)
	LRRTM4	Leucine rich repeat transmembrane neuronal 4. (540 aa)
	eef2k	Eukaryotic elongation factor 2 kinase. (737 aa)
	Caprin2	C1q domain-containing protein. (170 aa)
	ENSHCOP00000024149	Si:dkey-28o19.1. (627 aa)
	LOC109523178	Leucine rich repeat and fibronectin type III domain containing 5b. (794 aa)
	FRMPD4	FERM and PDZ domain containing 4. (1232 aa)
	SLITRK1	SLIT and NTRK like family member 1. (707 aa)
	ENSHCOP00000024885	Leucine-rich repeats and transmembrane domains 2a. (355 aa)
	NEUROD2-2	Neuronal differentiation 2. (359 aa)
	ENSHCOP00000025944	Leucine rich repeat containing 24. (468 aa)
	ENSHCOP00000025974	Uncharacterized protein. (298 aa)
	Reln	Uncharacterized protein. (877 aa)
	ENSHCOP00000026026	Uncharacterized protein. (863 aa)
	tanc1	Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1b. (1772 aa)
	abhd17b	Abhydrolase domain containing 17B. (288 aa)
	LOC109530100	Si:ch73-352p4.8. (478 aa)
	LOC109523356	Neuropilin; Belongs to the neuropilin family. (883 aa)
	LOC109509584	Protein ABHD17C-like. (94 aa)
	flrt2	Fibronectin leucine rich transmembrane protein 2. (660 aa)
	dbn1	Drebrin 1. (482 aa)
	NTNG2	Uncharacterized protein. (583 aa)
	LOC109520573	Eph receptor B3a. (925 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Caprin2	LOC109514330	ENSHCOP00000024058	ENSHCOP00000021767	C1q domain-containing protein.	Cell cycle associated protein 1a.	0.891
Caprin2	caprin1	ENSHCOP00000024058	ENSHCOP00000013553	C1q domain-containing protein.	Cell cycle associated protein 1b.	0.897
Colq	MUSK	ENSHCOP00000019922	ENSHCOP00000020208	Collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase.	Muscle associated receptor tyrosine kinase.	0.588
DAG1	LOC109515023	ENSHCOP00000011457	ENSHCOP00000008580	Dystroglycan 1.	Peptidase S72 domain-containing protein.	0.902
DAG1	agrn	ENSHCOP00000011457	ENSHCOP00000002641	Dystroglycan 1.	Agrin.	0.982
ENSHCOP00000006162	LOC109507195	ENSHCOP00000006162	ENSHCOP00000011786	Ig-like domain-containing protein.	Adhesion G protein-coupled receptor L1a; Belongs to the G-protein coupled receptor 2 family.	0.598
ENSHCOP00000006162	LOC109521300	ENSHCOP00000006162	ENSHCOP00000015335	Ig-like domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.598
ENSHCOP00000006162	adgrl2	ENSHCOP00000006162	ENSHCOP00000013930	Ig-like domain-containing protein.	Adhesion G protein-coupled receptor L2a; Belongs to the G-protein coupled receptor 2 family.	0.598
ENSHCOP00000007133	Mycbp2	ENSHCOP00000007133	ENSHCOP00000007094	Uncharacterized protein.	RING-type domain-containing protein.	0.933
ENSHCOP00000007872	LOC109507195	ENSHCOP00000007872	ENSHCOP00000011786	Uncharacterized protein.	Adhesion G protein-coupled receptor L1a; Belongs to the G-protein coupled receptor 2 family.	0.598
ENSHCOP00000007872	LOC109521300	ENSHCOP00000007872	ENSHCOP00000015335	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.598
ENSHCOP00000007872	adgrl2	ENSHCOP00000007872	ENSHCOP00000013930	Uncharacterized protein.	Adhesion G protein-coupled receptor L2a; Belongs to the G-protein coupled receptor 2 family.	0.598
ENSHCOP00000008601	LOC109507195	ENSHCOP00000008601	ENSHCOP00000011786	Ig-like domain-containing protein.	Adhesion G protein-coupled receptor L1a; Belongs to the G-protein coupled receptor 2 family.	0.598
ENSHCOP00000008601	LOC109521300	ENSHCOP00000008601	ENSHCOP00000015335	Ig-like domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.598
ENSHCOP00000008601	adgrl2	ENSHCOP00000008601	ENSHCOP00000013930	Ig-like domain-containing protein.	Adhesion G protein-coupled receptor L2a; Belongs to the G-protein coupled receptor 2 family.	0.598
ENSHCOP00000012870	flrt2	ENSHCOP00000012870	ENSHCOP00000027725	CortBP2 domain-containing protein.	Fibronectin leucine rich transmembrane protein 2.	0.474
ENSHCOP00000013336	ENSHCOP00000013347	ENSHCOP00000013336	ENSHCOP00000013347	Protein kinase domain-containing protein.	Uncharacterized protein.	0.945
ENSHCOP00000013336	LOC109507195	ENSHCOP00000013336	ENSHCOP00000011786	Protein kinase domain-containing protein.	Adhesion G protein-coupled receptor L1a; Belongs to the G-protein coupled receptor 2 family.	0.598
ENSHCOP00000013336	LOC109521300	ENSHCOP00000013336	ENSHCOP00000015335	Protein kinase domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.598
ENSHCOP00000013336	adgrl2	ENSHCOP00000013336	ENSHCOP00000013930	Protein kinase domain-containing protein.	Adhesion G protein-coupled receptor L2a; Belongs to the G-protein coupled receptor 2 family.	0.598