(40 nodes) Protein kinase A binding network (Hippocampus comes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	akap7	Uncharacterized protein. (439 aa)
	LOC109531651	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
	LOC109522988	Uncharacterized protein. (418 aa)
	acbd3	Acyl-Coenzyme A binding domain containing 3. (502 aa)
	dact3	Uncharacterized protein. (659 aa)
	akap10	A kinase (PRKA) anchor protein 10. (614 aa)
	LOC109508583	Protein kinase cAMP-dependent type I regulatory subunit alpha. (376 aa)
	akap17a	A kinase (PRKA) anchor protein 17A. (634 aa)
	arfgef1	ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited). (1501 aa)
	arfgef2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited). (1711 aa)
	prkar2a	Protein kinase, cAMP-dependent, regulatory, type II, alpha A. (391 aa)
	ENSHCOP00000005297	Uncharacterized protein. (99 aa)
	wasf1	WASP family member 1. (486 aa)
	myrip	Myosin VIIA and Rab interacting protein. (987 aa)
	akap1	A kinase (PRKA) anchor protein 1b. (828 aa)
	prrc1	Proline-rich coiled-coil 1. (436 aa)
	LOC109518303	Uncharacterized protein. (1291 aa)
	ENSHCOP00000013336	Protein kinase domain-containing protein. (472 aa)
	ENSHCOP00000013347	Uncharacterized protein. (1158 aa)
	wasf2	WASP family member 2. (398 aa)
	akap12	A kinase (PRKA) anchor protein 12b. (1313 aa)
	LOC109517921	WH2 domain-containing protein. (459 aa)
	ENSHCOP00000018864	RabBD domain-containing protein. (170 aa)
	akap11	A kinase (PRKA) anchor protein 11. (1786 aa)
	ENSHCOP00000021469	Si:dkeyp-81f3.4. (186 aa)
	ENSHCOP00000022636	FYVE_2 domain-containing protein. (73 aa)
	ENSHCOP00000024023	SPHK1 interactor, AKAP domain containing. (1181 aa)
	prkar1a	Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b. (380 aa)
	wasf3	WASP family member 3b. (490 aa)
	ENSHCOP00000026938	Uncharacterized protein. (102 aa)
	LOC109525772	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (571 aa)
	ENSHCOP00000028327	A kinase (PRKA) anchor protein 6. (1620 aa)
	LOC109518393	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (439 aa)
	LOC109522311	Protein kinase, cAMP-dependent, regulatory, type II, alpha, B. (404 aa)
	gsk3b	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (421 aa)
	LOC109529895	Uncharacterized protein; Belongs to the potassium channel family. (645 aa)
	prkar1b	Protein kinase, cAMP-dependent, regulatory, type I, beta. (382 aa)
	LOC109523228	Dishevelled-binding antagonist of beta-catenin 2. (853 aa)
	gskip	Gsk3b interacting protein. (133 aa)
	LOC109516667	Zgc:109889. (437 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000005297	akap10	ENSHCOP00000005297	ENSHCOP00000008119	Uncharacterized protein.	A kinase (PRKA) anchor protein 10.	0.407
ENSHCOP00000005297	akap11	ENSHCOP00000005297	ENSHCOP00000018915	Uncharacterized protein.	A kinase (PRKA) anchor protein 11.	0.525
ENSHCOP00000005297	akap7	ENSHCOP00000005297	ENSHCOP00000023691	Uncharacterized protein.	Uncharacterized protein.	0.407
ENSHCOP00000013336	ENSHCOP00000013347	ENSHCOP00000013336	ENSHCOP00000013347	Protein kinase domain-containing protein.	Uncharacterized protein.	0.945
ENSHCOP00000013347	ENSHCOP00000013336	ENSHCOP00000013347	ENSHCOP00000013336	Uncharacterized protein.	Protein kinase domain-containing protein.	0.945
ENSHCOP00000021469	akap1	ENSHCOP00000021469	ENSHCOP00000010203	Si:dkeyp-81f3.4.	A kinase (PRKA) anchor protein 1b.	0.407
ENSHCOP00000024023	akap1	ENSHCOP00000024023	ENSHCOP00000010203	SPHK1 interactor, AKAP domain containing.	A kinase (PRKA) anchor protein 1b.	0.466
ENSHCOP00000024023	akap10	ENSHCOP00000024023	ENSHCOP00000008119	SPHK1 interactor, AKAP domain containing.	A kinase (PRKA) anchor protein 10.	0.406
ENSHCOP00000026938	gskip	ENSHCOP00000026938	ENSHCOP00000001966	Uncharacterized protein.	Gsk3b interacting protein.	0.664
ENSHCOP00000028327	akap1	ENSHCOP00000028327	ENSHCOP00000010203	A kinase (PRKA) anchor protein 6.	A kinase (PRKA) anchor protein 1b.	0.602
ENSHCOP00000028327	akap10	ENSHCOP00000028327	ENSHCOP00000008119	A kinase (PRKA) anchor protein 6.	A kinase (PRKA) anchor protein 10.	0.471
ENSHCOP00000028327	akap7	ENSHCOP00000028327	ENSHCOP00000023691	A kinase (PRKA) anchor protein 6.	Uncharacterized protein.	0.617
LOC109508583	LOC109522311	ENSHCOP00000006717	ENSHCOP00000004553	Protein kinase cAMP-dependent type I regulatory subunit alpha.	Protein kinase, cAMP-dependent, regulatory, type II, alpha, B.	0.906
LOC109508583	LOC109522988	ENSHCOP00000006717	ENSHCOP00000009388	Protein kinase cAMP-dependent type I regulatory subunit alpha.	Uncharacterized protein.	0.415
LOC109508583	akap1	ENSHCOP00000006717	ENSHCOP00000010203	Protein kinase cAMP-dependent type I regulatory subunit alpha.	A kinase (PRKA) anchor protein 1b.	0.660
LOC109508583	akap10	ENSHCOP00000006717	ENSHCOP00000008119	Protein kinase cAMP-dependent type I regulatory subunit alpha.	A kinase (PRKA) anchor protein 10.	0.775
LOC109508583	akap7	ENSHCOP00000006717	ENSHCOP00000023691	Protein kinase cAMP-dependent type I regulatory subunit alpha.	Uncharacterized protein.	0.525
LOC109508583	prkar1a	ENSHCOP00000006717	ENSHCOP00000024364	Protein kinase cAMP-dependent type I regulatory subunit alpha.	Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b.	0.900
LOC109508583	prkar1b	ENSHCOP00000006717	ENSHCOP00000003239	Protein kinase cAMP-dependent type I regulatory subunit alpha.	Protein kinase, cAMP-dependent, regulatory, type I, beta.	0.901
LOC109508583	prkar2a	ENSHCOP00000006717	ENSHCOP00000005712	Protein kinase cAMP-dependent type I regulatory subunit alpha.	Protein kinase, cAMP-dependent, regulatory, type II, alpha A.	0.908