89 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109524974	Poly [ADP-ribose] polymerase. (1254 aa)
	ZNF830	Zinc finger protein 830. (344 aa)
	ten1	TEN1 subunit of CST complex. (143 aa)
	dffb	DNA fragmentation factor, beta polypeptide (caspase-activated DNase). (337 aa)
	xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1. (612 aa)
	LOC109522167	Poly [ADP-ribose] polymerase. (524 aa)
	mlh1	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (731 aa)
	otub1	Ubiquitin thioesterase. (266 aa)
	cdt1	Chromatin licensing and DNA replication factor 1. (617 aa)
	DONSON	Downstream neighbor of SON. (568 aa)
	igfbp2	Insulin-like growth factor binding protein 2a. (284 aa)
	ENSHCOP00000001721	H15 domain-containing protein. (117 aa)
	ENSHCOP00000001700	H15 domain-containing protein. (118 aa)
	pds5a	PDS5 cohesin associated factor A. (1213 aa)
	LOC109507177	Uncharacterized protein. (118 aa)
	ENPP7	Uncharacterized protein. (434 aa)
	Gmnc	Uncharacterized protein. (262 aa)
	terf2ip	BRCT domain-containing protein. (671 aa)
	OTUB2	OTU deubiquitinase, ubiquitin aldehyde binding 2. (256 aa)
	flcn	Folliculin. (550 aa)
	slx4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1637 aa)
	ENSHCOP00000017784	Uncharacterized protein. (123 aa)
	ENPP7-2	Ectonucleotide pyrophosphatase/phosphodiesterase 7. (266 aa)
	rad50	RAD50 homolog, double strand break repair protein. (1285 aa)
	fancb	FA complementation group B. (797 aa)
	msh3	MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR). (1057 aa)
	LOC109522412	Poly [ADP-ribose] polymerase. (528 aa)
	LOC109508080	Poly [ADP-ribose] polymerase. (1238 aa)
	tipin	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (281 aa)
	tp53bp1	Tumor protein p53 binding protein, 1. (1495 aa)
	ENSHCOP00000020772	RPA1 related single stranded DNA binding protein. (314 aa)
	pinx1	PIN2 (TERF1) interacting telomerase inhibitor 1. (326 aa)
	gnl3l	Guanine nucleotide binding protein-like 3 (nucleolar)-like. (568 aa)
	LOC109519106	Zgc:85936. (1042 aa)
	tinf2	TERF1 (TRF1)-interacting nuclear factor 2. (590 aa)
	ENSHCOP00000023012	Uncharacterized protein. (1155 aa)
	blm	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (966 aa)
	gtpbp4	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (635 aa)
	trip12	Thyroid hormone receptor interactor 12. (2055 aa)
	zranb3	Zinc finger, RAN-binding domain containing 3. (1127 aa)
	rtel1	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1042 aa)
	ubr5	Ubiquitin protein ligase E3 component n-recognin 5. (2539 aa)
	dcp2	Decapping mRNA 2. (402 aa)
	recql5	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (931 aa)
	Atr	Uncharacterized protein. (106 aa)
	ercc4	Excision repair cross-complementation group 4. (900 aa)
	LOC109530213	H1 histone family, member 0. (199 aa)
	exosc10	Exosome component 10. (890 aa)
	nat10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1035 aa)
	xrcc5	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (729 aa)
	parpbp	PARP1 binding protein. (493 aa)
	chek1	Checkpoint kinase 1; Belongs to the protein kinase superfamily. (462 aa)
	aunip	Uncharacterized protein. (264 aa)
	ENSHCOP00000027620	H15 domain-containing protein. (197 aa)
	ENSHCOP00000027708	H15 domain-containing protein. (132 aa)
	ercc6	Excision repair cross-complementation group 6. (1377 aa)
	LOC109518579	WAPL cohesin release factor b. (1173 aa)
	LOC109518507	Geminin DNA replication inhibitor. (224 aa)
	timeless	Timeless circadian clock. (1222 aa)
	rmi2	RecQ mediated genome instability 2. (158 aa)
	LOC109512334	Uncharacterized protein. (735 aa)
	Enpp7	Ectonucleotide pyrophosphatase/phosphodiesterase 7. (432 aa)
	ENSHCOP00000006085	Uncharacterized protein. (190 aa)
	ENSHCOP00000006088	H15 domain-containing protein. (139 aa)
	terf1	TRF domain-containing protein. (431 aa)
	ogg1	8-oxoguanine DNA glycosylase. (413 aa)
	smg6	SMG6 nonsense mediated mRNA decay factor. (1195 aa)
	Hmga2	Uncharacterized protein. (98 aa)
	pot1	Protection of telomeres 1 homolog. (842 aa)
	lig3	DNA ligase. (993 aa)
	ENSHCOP00000008088	Testis specific protein Y-linked; Belongs to the nucleosome assembly protein (NAP) family. (401 aa)
	LOC109512249	Zgc:153896. (449 aa)
	ENSHCOP00000008605	F-box domain-containing protein. (729 aa)
	men1	Multiple endocrine neoplasia I. (611 aa)
	ENSHCOP00000009180	Uncharacterized protein. (169 aa)
	Atm	TAN domain-containing protein. (311 aa)
	msh6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1375 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (492 aa)
	LOC109513483	Uncharacterized protein. (223 aa)
	cdan1	Codanin 1. (1038 aa)
	rif1	Replication timing regulatory factor 1. (2634 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (946 aa)
	LOC109520749	Uncharacterized protein. (534 aa)
	wapl	WAPL cohesin release factor a. (1146 aa)
	ercc1	Excision repair cross-complementation group 1. (338 aa)
	smarcal1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (839 aa)
	Thoc1	THO complex 1. (314 aa)
	terf2	HTH myb-type domain-containing protein. (606 aa)
	ENSHCOP00000014695	FAM35_C domain-containing protein. (255 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atm	Atr	ENSHCOP00000009193	ENSHCOP00000025135	TAN domain-containing protein.	Uncharacterized protein.	0.997
Atm	ENSHCOP00000009180	ENSHCOP00000009193	ENSHCOP00000009180	TAN domain-containing protein.	Uncharacterized protein.	0.929
Atm	ENSHCOP00000023012	ENSHCOP00000009193	ENSHCOP00000023012	TAN domain-containing protein.	Uncharacterized protein.	0.887
Atm	blm	ENSHCOP00000009193	ENSHCOP00000023146	TAN domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.909
Atm	chek1	ENSHCOP00000009193	ENSHCOP00000027175	TAN domain-containing protein.	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	0.982
Atm	ercc1	ENSHCOP00000009193	ENSHCOP00000014052	TAN domain-containing protein.	Excision repair cross-complementation group 1.	0.616
Atm	ercc4	ENSHCOP00000009193	ENSHCOP00000025158	TAN domain-containing protein.	Excision repair cross-complementation group 4.	0.610
Atm	mlh1	ENSHCOP00000009193	ENSHCOP00000002960	TAN domain-containing protein.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.846
Atm	msh2	ENSHCOP00000009193	ENSHCOP00000013100	TAN domain-containing protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.769
Atm	msh3	ENSHCOP00000009193	ENSHCOP00000019337	TAN domain-containing protein.	MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR).	0.548
Atm	msh6	ENSHCOP00000009193	ENSHCOP00000010111	TAN domain-containing protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.765
Atm	rad50	ENSHCOP00000009193	ENSHCOP00000018844	TAN domain-containing protein.	RAD50 homolog, double strand break repair protein.	0.995
Atm	recql5	ENSHCOP00000009193	ENSHCOP00000025061	TAN domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.742
Atm	rif1	ENSHCOP00000009193	ENSHCOP00000012872	TAN domain-containing protein.	Replication timing regulatory factor 1.	0.760
Atm	rmi2	ENSHCOP00000009193	ENSHCOP00000004996	TAN domain-containing protein.	RecQ mediated genome instability 2.	0.633
Atm	rtel1	ENSHCOP00000009193	ENSHCOP00000024322	TAN domain-containing protein.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.716
Atm	slx4	ENSHCOP00000009193	ENSHCOP00000017354	TAN domain-containing protein.	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).	0.703
Atm	terf1	ENSHCOP00000009193	ENSHCOP00000006155	TAN domain-containing protein.	TRF domain-containing protein.	0.693
Atm	timeless	ENSHCOP00000009193	ENSHCOP00000015927	TAN domain-containing protein.	Timeless circadian clock.	0.480
Atm	tp53bp1	ENSHCOP00000009193	ENSHCOP00000020451	TAN domain-containing protein.	Tumor protein p53 binding protein, 1.	0.974