STRINGSTRING
e2f7 e2f7 mms19 mms19 ENSHCOP00000022006 ENSHCOP00000022006 rfc3 rfc3 egf egf LOC109518982 LOC109518982 uchl5 uchl5 ppp1r10 ppp1r10 cebpg cebpg ENSHCOP00000020575 ENSHCOP00000020575 tp53bp1 tp53bp1 mfsd11 mfsd11 stpg4 stpg4 kmt5b kmt5b atrx atrx nek2 nek2 ino80d ino80d mapkapk5 mapkapk5 rnf8 rnf8 LOC109508080 LOC109508080 LOC109522412 LOC109522412 ENSHCOP00000019306 ENSHCOP00000019306 ENSHCOP00000019285 ENSHCOP00000019285 PRKCD PRKCD fancb fancb LOC109522455 LOC109522455 rgcc rgcc rad50 rad50 usp7 usp7 ino80 ino80 gins4-2 gins4-2 LOC109513861 LOC109513861 pias4 pias4 slx4 slx4 nsd2 nsd2 rfc5 rfc5 tfpt tfpt LOC109529213 LOC109529213 chtf18 chtf18 brca1 brca1 Brd8 Brd8 fh fh timeless timeless WIZ WIZ Spidr Spidr map2k7 map2k7 ssbp1 ssbp1 cct3 cct3 LOC109510758 LOC109510758 ENSHCOP00000014695 ENSHCOP00000014695 ercc8 ercc8 ercc1 ercc1 LOC109520749 LOC109520749 msh2 msh2 dtx3 dtx3 mecp2 mecp2 rif1 rif1 MGMT MGMT LOC109520029 LOC109520029 fam168a fam168a ercc2 ercc2 ppargc1a ppargc1a NOX4 NOX4 chtf8 chtf8 yeats4 yeats4 actr2 actr2 ENSHCOP00000011276 ENSHCOP00000011276 rfc4 rfc4 fbxo4 fbxo4 exosc3 exosc3 LOC109513483 LOC109513483 ENSHCOP00000010540 ENSHCOP00000010540 Ucn Ucn ENSHCOP00000010439 ENSHCOP00000010439 dhx9 dhx9 tigar tigar stoml2 stoml2 Atm Atm ENSHCOP00000009180 ENSHCOP00000009180 prkdc prkdc ENSHCOP00000008991 ENSHCOP00000008991 LOC109508453 LOC109508453 ENSHCOP00000008755 ENSHCOP00000008755 ENSHCOP00000008732 ENSHCOP00000008732 ENSHCOP00000008597 ENSHCOP00000008597 ccdc117 ccdc117 LOC109521469 LOC109521469 pot1 pot1 LOC109523136 LOC109523136 LOC109527038 LOC109527038 ENSHCOP00000005103 ENSHCOP00000005103 vps72 vps72 LOC109527782 LOC109527782 dbf4 dbf4 babam1 babam1 rad51ap1 rad51ap1 ptprc ptprc LOC109513557 LOC109513557 LOC109527740 LOC109527740 LOC109509139 LOC109509139 GREM1 GREM1 baz1a baz1a dkc1 dkc1 myc myc sirt6 sirt6 LOC109513883 LOC109513883 naf1 naf1 tmem161a tmem161a LOC109513825 LOC109513825 nvl nvl LOC109512602 LOC109512602 gfer gfer LOC109524974 LOC109524974 faf1 faf1 trrap trrap ENSHCOP00000001726 ENSHCOP00000001726 LOC109521650 LOC109521650 cdt1 cdt1 bcl7a bcl7a LOC109511462 LOC109511462 dhx36 dhx36 LOC109517783 LOC109517783 mlh1 mlh1 ENSHCOP00000003038 ENSHCOP00000003038 LOC109524269 LOC109524269 LOC109523155 LOC109523155 cct2 cct2 LOC109522167 LOC109522167 ENSHCOP00000007515 ENSHCOP00000007515 e2f8 e2f8 prkcq prkcq mrgbp mrgbp xrcc1 xrcc1 cct5 cct5 rad51 rad51 abraxas1 abraxas1 map3k4 map3k4 prim2 prim2 ENSHCOP00000024593 ENSHCOP00000024593 pnkp pnkp dna2 dna2 wt1 wt1 Atr Atr gins3 gins3 otud4 otud4 wdr48 wdr48 gins2 gins2 tbx21 tbx21 hmces hmces ENSHCOP00000026411 ENSHCOP00000026411 bax bax xrcc5 xrcc5 foxm1 foxm1 ENSHCOP00000027055 ENSHCOP00000027055 ENSHCOP00000027094 ENSHCOP00000027094 actl6a actl6a polg2 polg2 rnf168 rnf168 Slf1 Slf1 cdc7 cdc7 mcrs1 mcrs1 dmap1 dmap1 hdgfl2 hdgfl2 nfrkb nfrkb ercc6 ercc6 eya3 eya3 LOC109521304 LOC109521304 ino80e ino80e LOC109508375 LOC109508375 LOC109529502 LOC109529502 rfc2 rfc2 parp1 parp1 babam2 babam2 Brcc3 Brcc3 arid2 arid2 LOC109527621 LOC109527621 wrap53 wrap53
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
e2f7E2F transcription factor 7. (662 aa)
mms19MMS19 homolog, cytosolic iron-sulfur assembly component. (929 aa)
ENSHCOP00000022006Uncharacterized protein. (852 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
egfEpidermal growth factor. (979 aa)
LOC109518982Enhancer of polycomb homolog. (835 aa)
uchl5Ubiquitin carboxyl-terminal hydrolase. (329 aa)
ppp1r10Protein phosphatase 1, regulatory subunit 10. (832 aa)
cebpgCCAAT enhancer binding protein gamma. (246 aa)
ENSHCOP00000020575PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (216 aa)
tp53bp1Tumor protein p53 binding protein, 1. (1495 aa)
mfsd11Uncharacterized protein. (405 aa)
stpg4Uncharacterized protein. (219 aa)
kmt5bLysine methyltransferase 5B. (862 aa)
atrxATRX chromatin remodeler. (1645 aa)
nek2NIMA-related kinase 2. (425 aa)
ino80dINO80 complex subunit Da. (979 aa)
mapkapk5MAPK activated protein kinase 5. (471 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (578 aa)
LOC109508080Poly [ADP-ribose] polymerase. (1238 aa)
LOC109522412Poly [ADP-ribose] polymerase. (528 aa)
ENSHCOP00000019306Sirtuin 1. (369 aa)
ENSHCOP00000019285Deacetylase sirtuin-type domain-containing protein. (166 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (682 aa)
fancbFA complementation group B. (797 aa)
LOC109522455Protein kinase C. (678 aa)
rgccRegulator of cell cycle. (130 aa)
rad50RAD50 homolog, double strand break repair protein. (1285 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1111 aa)
ino80INO80 complex ATPase subunit. (1543 aa)
gins4-2DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (222 aa)
LOC109513861Homeobox containing 1a. (253 aa)
pias4Protein inhibitor of activated STAT, 4a. (488 aa)
slx4SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1637 aa)
nsd2Nuclear receptor binding SET domain protein 2. (1265 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
tfptTCF3 (E2A) fusion partner. (198 aa)
LOC109529213Bromodomain and PHD finger containing, 3a. (1200 aa)
chtf18CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae). (922 aa)
brca1Uncharacterized protein. (1141 aa)
Brd8Uncharacterized protein. (79 aa)
fhFumarate hydratase. (499 aa)
timelessTimeless circadian clock. (1222 aa)
WIZWIZ zinc finger. (945 aa)
SpidrDUF4503 domain-containing protein. (454 aa)
map2k7Mitogen-activated protein kinase kinase 7. (422 aa)
ssbp1Single-stranded DNA binding protein 1. (147 aa)
cct3T-complex protein 1 subunit gamma. (540 aa)
LOC109510758Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
ENSHCOP00000014695FAM35_C domain-containing protein. (255 aa)
ercc8Excision repair cross-complementation group 8. (384 aa)
ercc1Excision repair cross-complementation group 1. (338 aa)
LOC109520749Uncharacterized protein. (534 aa)
msh2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (946 aa)
dtx3Zgc:66440. (358 aa)
mecp2Methyl CpG binding protein 2. (848 aa)
rif1Replication timing regulatory factor 1. (2634 aa)
MGMTO-6-methylguanine-DNA methyltransferase. (189 aa)
LOC109520029WT1 transcription factor a. (416 aa)
fam168aFamily with sequence similarity 168 member A. (226 aa)
ercc2Excision repair cross-complementation group 2. (591 aa)
ppargc1aPeroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (915 aa)
NOX4NADPH oxidase 4. (499 aa)
chtf8CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (135 aa)
yeats4YEATS domain containing 4. (226 aa)
actr2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (394 aa)
ENSHCOP00000011276KIND domain-containing protein. (143 aa)
rfc4Replication factor C (activator 1) 4. (331 aa)
fbxo4F-box protein 4. (364 aa)
exosc3Exosome component 3. (246 aa)
LOC109513483Uncharacterized protein. (223 aa)
ENSHCOP00000010540Helicase, POLQ like. (557 aa)
UcnCRF domain-containing protein. (134 aa)
ENSHCOP00000010439Spire-type actin nucleation factor 1a. (781 aa)
dhx9DEAH (Asp-Glu-Ala-His) box helicase 9. (1267 aa)
tigarTP53 induced glycolysis regulatory phosphatase a. (263 aa)
stoml2Stomatin (EPB72)-like 2. (349 aa)
AtmTAN domain-containing protein. (311 aa)
ENSHCOP00000009180Uncharacterized protein. (169 aa)
prkdcProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3890 aa)
ENSHCOP00000008991GIY-YIG domain-containing protein. (84 aa)
LOC109508453Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (241 aa)
ENSHCOP00000008755Protein kinase domain-containing protein. (396 aa)
ENSHCOP00000008732Pogo transposable element derived with ZNF domain b. (1733 aa)
ENSHCOP00000008597HTH_Tnp_Tc3_2 domain-containing protein. (219 aa)
ccdc117Si:ch211-102c2.7. (273 aa)
LOC109521469SET domain and mariner transposase fusion gene. (295 aa)
pot1Protection of telomeres 1 homolog. (842 aa)
LOC109523136Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (532 aa)
LOC109527038ATPase family AAA domain containing 5a. (1619 aa)
ENSHCOP00000005103Uncharacterized protein. (167 aa)
vps72Vacuolar protein sorting 72 homolog a. (371 aa)
LOC109527782Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (449 aa)
dbf4DBF4-type domain-containing protein. (388 aa)
babam1BRISC and BRCA1 A complex member 1. (373 aa)
rad51ap1RAD51_interact domain-containing protein. (275 aa)
ptprcProtein tyrosine phosphatase receptor type C. (1232 aa)
LOC109513557CD40 molecule, TNF receptor superfamily member 5. (309 aa)
LOC109527740Lysine methyltransferase 5C. (429 aa)
LOC109509139Uncharacterized protein. (138 aa)
GREM1Gremlin; Belongs to the DAN family. (177 aa)
baz1aBromodomain adjacent to zinc finger domain 1A. (1129 aa)
dkc1Dyskeratosis congenita 1, dyskerin. (504 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (433 aa)
sirt6Sirtuin 6. (347 aa)
LOC109513883Homeobox containing 1a. (367 aa)
naf1Uncharacterized protein. (381 aa)
tmem161aTransmembrane protein 161A. (487 aa)
LOC109513825Major facilitator superfamily domain containing 11. (441 aa)
nvlNuclear VCP like. (848 aa)
LOC109512602Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (421 aa)
gferSulfhydryl oxidase. (190 aa)
LOC109524974Poly [ADP-ribose] polymerase. (1254 aa)
faf1Fas (TNFRSF6) associated factor 1. (658 aa)
trrapTransformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family. (3534 aa)
ENSHCOP00000001726Uncharacterized protein. (267 aa)
LOC109521650Cdkn1a interacting zinc finger protein 1a. (668 aa)
cdt1Chromatin licensing and DNA replication factor 1. (617 aa)
bcl7aBAF chromatin remodeling complex subunit BCL7A. (190 aa)
LOC109511462Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (471 aa)
dhx36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (966 aa)
LOC109517783Bromodomain and PHD finger containing, 3b. (1155 aa)
mlh1MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (731 aa)
ENSHCOP00000003038Uncharacterized protein. (850 aa)
LOC109524269Bromodomain containing 8. (761 aa)
LOC109523155Sirtuin 1. (657 aa)
cct2Chaperonin containing TCP1, subunit 2 (beta). (535 aa)
LOC109522167Poly [ADP-ribose] polymerase. (524 aa)
ENSHCOP00000007515Uncharacterized protein. (89 aa)
e2f8E2F transcription factor 8. (866 aa)
prkcqProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (710 aa)
mrgbpMRG/MORF4L binding protein. (211 aa)
xrcc1X-ray repair complementing defective repair in Chinese hamster cells 1. (612 aa)
cct5Chaperonin containing TCP1, subunit 5 (epsilon). (541 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa)
abraxas1Abraxas 1, BRCA1 A complex subunit. (351 aa)
map3k4Mitogen-activated protein kinase kinase kinase 4. (1500 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (519 aa)
ENSHCOP00000024593Uncharacterized protein. (129 aa)
pnkpPolynucleotide kinase 3'-phosphatase. (609 aa)
dna2DNA replication helicase/nuclease 2. (1305 aa)
wt1WT1 transcription factor b. (426 aa)
AtrUncharacterized protein. (106 aa)
gins3GINS complex subunit 3. (211 aa)
otud4OTU domain-containing protein. (892 aa)
wdr48WD repeat domain 48b. (677 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa)
tbx21T-box transcription factor 21. (582 aa)
hmcesAbasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (323 aa)
ENSHCOP00000026411Uncharacterized protein. (408 aa)
baxBCL2 associated X, apoptosis regulator a. (255 aa)
xrcc5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (729 aa)
foxm1Forkhead box M1. (642 aa)
ENSHCOP00000027055Cytochrome P450, family 1, subfamily C, polypeptide 2; Belongs to the cytochrome P450 family. (519 aa)
ENSHCOP00000027094Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (520 aa)
actl6aActin-like 6A; Belongs to the actin family. (429 aa)
polg2Polymerase (DNA directed), gamma 2, accessory subunit. (454 aa)
rnf168RING-type domain-containing protein. (444 aa)
Slf1Uncharacterized protein. (142 aa)
cdc7Cell division cycle 7 homolog (S. cerevisiae); Belongs to the protein kinase superfamily. (486 aa)
mcrs1Microspherule protein 1. (464 aa)
dmap1DNA methyltransferase 1 associated protein 1. (480 aa)
hdgfl2HDGF like 2. (621 aa)
nfrkbNuclear factor related to kappaB binding protein. (1123 aa)
ercc6Excision repair cross-complementation group 6. (1377 aa)
eya3Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (562 aa)
LOC109521304CTCK domain-containing protein. (129 aa)
ino80eINO80 complex subunit E. (236 aa)
LOC109508375Zgc:101810; Belongs to the actin family. (394 aa)
LOC109529502Enhancer of polycomb homolog. (775 aa)
rfc2Replication factor C (activator 1) 2. (244 aa)
parp1Poly [ADP-ribose] polymerase. (1020 aa)
babam2BRISC and BRCA1 A complex member 2. (366 aa)
Brcc3BRCA1/BRCA2-containing complex, subunit 3. (284 aa)
arid2AT rich interactive domain 2 (ARID, RFX-like). (1600 aa)
LOC109527621Uncharacterized protein. (327 aa)
wrap53WD repeat containing, antisense to TP53. (533 aa)
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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