STRINGSTRING
smo smo ripk2 ripk2 commd6 commd6 LOC109521304 LOC109521304 ripk1 ripk1 ENSHCOP00000027903 ENSHCOP00000027903 sufu sufu LOC109521640 LOC109521640 LOC109527991 LOC109527991 pprc1 pprc1 ENSHCOP00000027094 ENSHCOP00000027094 ENSHCOP00000027055 ENSHCOP00000027055 neurog1 neurog1 LOC109509783 LOC109509783 LOC109532181 LOC109532181 sav1 sav1 ENSHCOP00000026026 ENSHCOP00000026026 Reln Reln LOC109529128 LOC109529128 ENSHCOP00000025919 ENSHCOP00000025919 LOC109516272 LOC109516272 pex14 pex14 taf12 taf12 LOC109516174 LOC109516174 JMY-2 JMY-2 prkcz prkcz LOC109514850 LOC109514850 ENSHCOP00000024644 ENSHCOP00000024644 ENSHCOP00000024540 ENSHCOP00000024540 mtdh mtdh LOC109511429 LOC109511429 card14 card14 ripk4 ripk4 LOC109531636 LOC109531636 CYTL1 CYTL1 LOC109531236 LOC109531236 TAF3 TAF3 tnfrsf19 tnfrsf19 CRTC2 CRTC2 LOC109531092 LOC109531092 traip traip Trim37 Trim37 commd1 commd1 clu clu map2k5 map2k5 Ufl1 Ufl1 LOC109518471 LOC109518471 il10 il10 Adgrf1 Adgrf1 card11 card11 LOC109525597 LOC109525597 LOC109521023 LOC109521023 crtc3 crtc3 Crtc3 Crtc3 cebpg cebpg setd6 setd6 ENSHCOP00000020224 ENSHCOP00000020224 nr0b2 nr0b2 JMY JMY rb1 rb1 prdx3 prdx3 LOC109520294 LOC109520294 e2f1 e2f1 ENSHCOP00000019306 ENSHCOP00000019306 ENSHCOP00000019285 ENSHCOP00000019285 zc3h12a zc3h12a LOC109517754 LOC109517754 psmd10 psmd10 rgcc rgcc LOC109520405 LOC109520405 LOC109530564 LOC109530564 LOC109511042 LOC109511042 id1 id1 gas6 gas6 cunh3orf33 cunh3orf33 usp7 usp7 myocd myocd LOC109520568 LOC109520568 id3 id3 LOC109511931 LOC109511931 LOC109511934 LOC109511934 nod2 nod2 traf3 traf3 srf srf ENSHCOP00000017013 ENSHCOP00000017013 LOC109521217 LOC109521217 LOC109522580 LOC109522580 trim62 trim62 LOC109525897 LOC109525897 ENSHCOP00000016349 ENSHCOP00000016349 pkd1 pkd1 ENSHCOP00000016159 ENSHCOP00000016159 ENSHCOP00000016131 ENSHCOP00000016131 terf2ip terf2ip psma6 psma6 LOC109508122 LOC109508122 sigirr sigirr LOC109512681 LOC109512681 ENSHCOP00000015643 ENSHCOP00000015643 traf6 traf6 HAND1 HAND1 EIF2AK4 EIF2AK4 chp1 chp1 LOC109518553 LOC109518553 LOC109525219 LOC109525219 ndp ndp prmt2 prmt2 dap dap nwd2 nwd2 cth cth LOC109510880 LOC109510880 ENSHCOP00000013481 ENSHCOP00000013481 RNF220-2 RNF220-2 RNF220 RNF220 irak1 irak1 ctnnbip1 ctnnbip1 LOC109527442 LOC109527442 LOC109527501 LOC109527501 LOC109513432 LOC109513432 fzd4 fzd4 ppargc1a ppargc1a ENSHCOP00000011594 ENSHCOP00000011594 ENSHCOP00000011559 ENSHCOP00000011559 ENSHCOP00000011367 ENSHCOP00000011367 LOC109512247 LOC109512247 LOC109517508 LOC109517508 rbck1 rbck1 LOC109510255 LOC109510255 LOC109528183 LOC109528183 kdm1a kdm1a dhx9 dhx9 ENSHCOP00000010147 ENSHCOP00000010147 ENSHCOP00000009932 ENSHCOP00000009932 ENSHCOP00000009710 ENSHCOP00000009710 ENSHCOP00000009513 ENSHCOP00000009513 adcy8 adcy8 tnfrsf11a tnfrsf11a LOC109518125 LOC109518125 men1 men1 LOC109524061 LOC109524061 mbtps2 mbtps2 SRF SRF nr1h4 nr1h4 dhx33 dhx33 wfs1 wfs1 bhlhe40 bhlhe40 eif2ak2 eif2ak2 nfkbil1 nfkbil1 Sox2 Sox2 cib1 cib1 LOC109512841 LOC109512841 ENSHCOP00000007842 ENSHCOP00000007842 GREM1 GREM1 sox1 sox1 acod1 acod1 ENSHCOP00000007014 ENSHCOP00000007014 glis2 glis2 LOC109519522 LOC109519522 cops5 cops5 LOC109513557 LOC109513557 LOC109524669 LOC109524669 CRTC1 CRTC1 LOC109516310 LOC109516310 ENSHCOP00000006190 ENSHCOP00000006190 ENSHCOP00000006060 ENSHCOP00000006060 LOC109525796 LOC109525796 WNT2B WNT2B AR AR lrp6 lrp6 LOC109513802 LOC109513802 rnf25 rnf25 LOC109524267 LOC109524267 trappc9 trappc9 rlim rlim LOC109517693 LOC109517693 LOC109523136 LOC109523136 LOC109521254 LOC109521254 LOC109511789 LOC109511789 fancd2 fancd2 LOC109523155 LOC109523155 commd7 commd7 ENSHCOP00000003150 ENSHCOP00000003150 ENSHCOP00000003134 ENSHCOP00000003134 cdk5rap3 cdk5rap3 tnfsf11 tnfsf11 LOC109516682 LOC109516682 LOC109524475 LOC109524475 LOC109521498 LOC109521498 NR0B1 NR0B1 gca gca arhgef2 arhgef2 faf1 faf1 LOC109516522 LOC109516522 tnfaip3 tnfaip3 ENSHCOP00000001334 ENSHCOP00000001334 ENSHCOP00000001320 ENSHCOP00000001320 nupr1 nupr1 LOC109510598 LOC109510598 ENSHCOP00000000810 ENSHCOP00000000810 otulin otulin ddit3 ddit3 LOC109510605 LOC109510605 cyld cyld rwdd1 rwdd1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (808 aa)
ripk2Receptor-interacting serine-threonine kinase 2. (585 aa)
commd6COMM domain containing 6. (199 aa)
LOC109521304CTCK domain-containing protein. (129 aa)
ripk1Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (677 aa)
ENSHCOP00000027903annotation not available (76 aa)
sufuSuppressor of fused homolog. (469 aa)
LOC109521640E3 ubiquitin-protein ligase. (861 aa)
LOC109527991Uncharacterized protein. (485 aa)
pprc1PPARG related coactivator 1. (1232 aa)
ENSHCOP00000027094Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (520 aa)
ENSHCOP00000027055Cytochrome P450, family 1, subfamily C, polypeptide 2; Belongs to the cytochrome P450 family. (519 aa)
neurog1Neurogenin 1. (160 aa)
LOC109509783Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (308 aa)
LOC109532181Phospholipid phosphatase 3. (314 aa)
sav1Salvador family WW domain containing protein 1. (403 aa)
ENSHCOP00000026026Uncharacterized protein. (863 aa)
RelnUncharacterized protein. (877 aa)
LOC109529128Uncharacterized protein. (716 aa)
ENSHCOP00000025919Uncharacterized protein. (137 aa)
LOC109516272Component of inhibitor of nuclear factor kappa B kinase complex. (739 aa)
pex14Peroxisomal biogenesis factor 14. (368 aa)
taf12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (189 aa)
LOC109516174Tripartite motif containing 8b. (583 aa)
JMY-2Junction mediating and regulatory protein, p53 cofactor. (745 aa)
prkczProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (556 aa)
LOC109514850E1A binding protein p300 b. (2669 aa)
ENSHCOP00000024644annotation not available (274 aa)
ENSHCOP00000024540Uncharacterized protein. (161 aa)
mtdhUncharacterized protein. (544 aa)
LOC109511429Wolfram syndrome 1a (wolframin). (742 aa)
card14Caspase recruitment domain family, member 14. (744 aa)
ripk4Receptor-interacting serine-threonine kinase 4. (799 aa)
LOC109531636Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (388 aa)
CYTL1Cytokine like 1. (146 aa)
LOC109531236MALT paracaspase 3. (638 aa)
TAF3TATA-box binding protein associated factor 3. (654 aa)
tnfrsf19Tumor necrosis factor receptor superfamily, member 19. (339 aa)
CRTC2CREB regulated transcription coactivator 2. (748 aa)
LOC109531092Ribosomal protein S6 kinase. (784 aa)
traipTRAF-interacting protein. (449 aa)
Trim37RING-type domain-containing protein. (99 aa)
commd1Copper metabolism (Murr1) domain containing 1. (191 aa)
cluClusterin; Belongs to the clusterin family. (461 aa)
map2k5Mitogen-activated protein kinase kinase 5. (409 aa)
Ufl1UFM1-specific ligase 1. (727 aa)
LOC109518471Uncharacterized protein. (767 aa)
il10Uncharacterized protein. (236 aa)
Adgrf1G_PROTEIN_RECEP_F2_4 domain-containing protein. (281 aa)
card11Caspase recruitment domain family, member 11. (1163 aa)
LOC109525597Formyl peptide receptor 1; Belongs to the G-protein coupled receptor 1 family. (379 aa)
LOC109521023Tumor necrosis factor b (TNF superfamily, member 2); Belongs to the tumor necrosis factor family. (266 aa)
crtc3CREB regulated transcription coactivator 3. (456 aa)
Crtc3TORC_N domain-containing protein. (94 aa)
cebpgCCAAT enhancer binding protein gamma. (246 aa)
setd6N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. (448 aa)
ENSHCOP00000020224Clusterin; Belongs to the clusterin family. (439 aa)
nr0b2Nuclear receptor subfamily 0, group B, member 2a. (255 aa)
JMYJunction mediating and regulatory protein, p53 cofactor. (845 aa)
rb1Retinoblastoma 1. (903 aa)
prdx3Peroxiredoxin 3. (241 aa)
LOC109520294SRY-box transcription factor 19b. (304 aa)
e2f1E2F transcription factor 1. (428 aa)
ENSHCOP00000019306Sirtuin 1. (369 aa)
ENSHCOP00000019285Deacetylase sirtuin-type domain-containing protein. (166 aa)
zc3h12aSi:dkey-206d17.12. (517 aa)
LOC109517754Nuclear receptor subfamily 1, group H, member 5. (488 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (226 aa)
rgccRegulator of cell cycle. (130 aa)
LOC109520405TNF receptor-associated factor. (487 aa)
LOC109530564SRY-box transcription factor 1a. (368 aa)
LOC109511042Uncharacterized protein. (477 aa)
id1Inhibitor of DNA binding 1, HLH protein. (132 aa)
gas6Uncharacterized protein. (619 aa)
cunh3orf33C18h3orf33 homolog (H. sapiens). (257 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1111 aa)
myocdSAP domain-containing protein. (777 aa)
LOC109520568acidPPc domain-containing protein. (311 aa)
id3Inhibitor of DNA binding 3. (115 aa)
LOC109511931SRY-box transcription factor 3. (303 aa)
LOC109511934TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (227 aa)
nod2Nucleotide-binding oligomerization domain containing 2. (949 aa)
traf3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (579 aa)
srfSerum response factor b. (601 aa)
ENSHCOP00000017013Uncharacterized protein. (430 aa)
LOC109521217Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1102 aa)
LOC109522580BHLH domain-containing protein. (412 aa)
trim62Tripartite motif containing 62, tandem duplicate 1. (475 aa)
LOC109525897Uncharacterized protein. (532 aa)
ENSHCOP00000016349Nuclear protein 1a. (76 aa)
pkd1Polycystic kidney disease 1a. (4575 aa)
ENSHCOP00000016159Ring finger protein 220b. (225 aa)
ENSHCOP00000016131Uncharacterized protein. (315 aa)
terf2ipBRCT domain-containing protein. (671 aa)
psma6Proteasome subunit alpha type. (246 aa)
LOC109508122Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (283 aa)
sigirrSingle immunoglobulin and toll-interleukin 1 receptor (TIR) domain. (523 aa)
LOC109512681RING-type domain-containing protein. (553 aa)
ENSHCOP00000015643Si:dkey-29b11.3. (160 aa)
traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (562 aa)
HAND1Heart and neural crest derivatives expressed 1. (204 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1478 aa)
chp1Calcineurin-like EF-hand protein 1. (195 aa)
LOC109518553Protein kinase domain-containing protein. (796 aa)
LOC109525219NK3 homeobox 1. (189 aa)
ndpNorrin cystine knot growth factor NDP. (136 aa)
prmt2Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (378 aa)
dapDeath-associated protein. (105 aa)
nwd2NACHT and WD repeat domain containing 2. (1723 aa)
cthCystathionase (cystathionine gamma-lyase), like. (411 aa)
LOC109510880Hairy-related 13. (221 aa)
ENSHCOP00000013481Reelin domain-containing protein. (267 aa)
RNF220-2Ring finger protein 220a. (338 aa)
RNF220Uncharacterized protein. (255 aa)
irak1Interleukin-1 receptor-associated kinase 1. (606 aa)
ctnnbip1Catenin, beta interacting protein 1. (81 aa)
LOC109527442Junction plakoglobin a. (699 aa)
LOC109527501RRM domain-containing protein. (893 aa)
LOC109513432Interleukin-1. (238 aa)
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (531 aa)
ppargc1aPeroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (915 aa)
ENSHCOP00000011594Uncharacterized protein. (127 aa)
ENSHCOP00000011559Actin binding Rho activating protein b. (558 aa)
ENSHCOP00000011367PLAT domain-containing protein. (274 aa)
LOC109512247Uncharacterized protein. (205 aa)
LOC109517508cAMP responsive element binding protein 3-like 3 like. (497 aa)
rbck1RanBP-type and C3HC4-type zinc finger containing 1. (504 aa)
LOC109510255Actin binding Rho activating protein a. (346 aa)
LOC109528183Ribosomal protein S6 kinase. (844 aa)
kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (839 aa)
dhx9DEAH (Asp-Glu-Ala-His) box helicase 9. (1267 aa)
ENSHCOP00000010147Endothelin 1. (182 aa)
ENSHCOP00000009932Tripartite motif containing 32. (638 aa)
ENSHCOP00000009710Si:ch73-174h16.4. (288 aa)
ENSHCOP00000009513Uncharacterized protein. (576 aa)
adcy8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1094 aa)
tnfrsf11aTumor necrosis factor receptor superfamily, member 11a, NFKB activator. (595 aa)
LOC109518125Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (995 aa)
men1Multiple endocrine neoplasia I. (611 aa)
LOC109524061Uncharacterized protein. (935 aa)
mbtps2Membrane-bound transcription factor peptidase, site 2. (491 aa)
SRFSerum response factor. (344 aa)
nr1h4Nuclear receptor subfamily 1, group H, member 4. (476 aa)
dhx33DEAH (Asp-Glu-Ala-His) box polypeptide 33. (681 aa)
wfs1Uncharacterized protein. (382 aa)
bhlhe40Basic helix-loop-helix family, member e40. (406 aa)
eif2ak2Uncharacterized protein. (609 aa)
nfkbil1Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1. (335 aa)
Sox2SRY-box transcription factor 2. (327 aa)
cib1Calcium and integrin binding 1 (calmyrin). (189 aa)
LOC109512841E1A binding protein p300 a. (2561 aa)
ENSHCOP00000007842Si:dkey-23i12.7. (118 aa)
GREM1Gremlin; Belongs to the DAN family. (177 aa)
sox1HMG box domain-containing protein. (338 aa)
acod1Aconitate decarboxylase 1. (506 aa)
ENSHCOP00000007014Interleukin-1 receptor-associated kinase 3. (331 aa)
glis2GLIS family zinc finger 2b. (475 aa)
LOC109519522ANK_REP_REGION domain-containing protein. (340 aa)
cops5COP9 signalosome subunit 5. (333 aa)
LOC109513557CD40 molecule, TNF receptor superfamily member 5. (309 aa)
LOC109524669Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1110 aa)
CRTC1CREB regulated transcription coactivator 1b. (564 aa)
LOC109516310Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (448 aa)
ENSHCOP00000006190Adhesion G protein-coupled receptor F7; Belongs to the G-protein coupled receptor 2 family. (424 aa)
ENSHCOP00000006060Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (464 aa)
LOC109525796Inhibitor of nuclear factor kappa B kinase subunit beta. (674 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
ARAndrogen receptor. (703 aa)
lrp6Low density lipoprotein receptor-related protein 6. (1518 aa)
LOC109513802Phospholipase A(2). (162 aa)
rnf25Ring finger protein 25. (423 aa)
LOC109524267Peroxisome proliferator-activated receptor gamma, coactivator 1 beta. (748 aa)
trappc9Trafficking protein particle complex 9. (1134 aa)
rlimRing finger protein, LIM domain interacting. (642 aa)
LOC109517693TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
LOC109523136Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (532 aa)
LOC109521254Hes family bHLH transcription factor 6. (226 aa)
LOC109511789E3 ubiquitin-protein ligase. (837 aa)
fancd2FA complementation group D2. (1328 aa)
LOC109523155Sirtuin 1. (657 aa)
commd7COMM domain containing 7. (199 aa)
ENSHCOP00000003150Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (172 aa)
ENSHCOP00000003134Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (151 aa)
cdk5rap3CDK5 regulatory subunit associated protein 3. (501 aa)
tnfsf11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (266 aa)
LOC109516682FOS-like antigen 1a. (338 aa)
LOC109524475Uncharacterized protein. (661 aa)
LOC109521498Cylindromatosis (turban tumor syndrome), b. (711 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (321 aa)
gcaGrancalcin. (234 aa)
arhgef2Rho guanine nucleotide exchange factor (GEF) 1a. (880 aa)
faf1Fas (TNFRSF6) associated factor 1. (658 aa)
LOC109516522Uncharacterized protein. (727 aa)
tnfaip3Tumor necrosis factor, alpha-induced protein 3. (753 aa)
ENSHCOP00000001334Uncharacterized protein. (281 aa)
ENSHCOP00000001320ARID domain-containing protein. (158 aa)
nupr1Nuclear protein 1b. (74 aa)
LOC109510598TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
ENSHCOP00000000810MALT paracaspase 2. (513 aa)
otulinUncharacterized protein. (663 aa)
ddit3DNA-damage-inducible transcript 3. (295 aa)
LOC109510605Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
cyldCylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (771 aa)
rwdd1RWD domain containing 1. (240 aa)
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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