54 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109510814	ABC transporter domain-containing protein. (644 aa)
	scap	SREBF chaperone. (1275 aa)
	pid1	Phosphotyrosine interaction domain containing 1. (225 aa)
	P2RY6	Pyrimidinergic receptor P2Y6; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	prkaa2	Non-specific serine/threonine protein kinase. (548 aa)
	guca1a	Guanylate cyclase activator 1A. (210 aa)
	clybl	Citrate lyase beta like. (338 aa)
	ppard	Peroxisome proliferator-activated receptor delta b. (375 aa)
	LOC109531655	Apolipoprotein Eb. (297 aa)
	LOC109531653	Uncharacterized protein. (270 aa)
	ENSHCOP00000014775	Insulin-like growth factor 1. (181 aa)
	mlycd	Malonyl-CoA decarboxylase. (504 aa)
	srebf1	Sterol regulatory element binding transcription factor 1. (1179 aa)
	ENSHCOP00000013250	Uncharacterized protein. (113 aa)
	LOC109517974	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (173 aa)
	LOC109513432	Interleukin-1. (238 aa)
	ppargc1a	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (915 aa)
	ncs1	Neuronal calcium sensor 1a. (190 aa)
	apoa4	Uncharacterized protein. (267 aa)
	LOC109520147	ATP-binding cassette, sub-family D (ALD), member 2. (731 aa)
	LOC109523728	Peroxisome proliferator-activated receptor alpha a. (479 aa)
	MTLN	Mitoregulin. (56 aa)
	srebf2	Sterol regulatory element binding transcription factor 2. (1122 aa)
	prkaa1	Non-specific serine/threonine protein kinase. (569 aa)
	LOC109523155	Sirtuin 1. (657 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha b. (430 aa)
	LOC109512469	Guanylate cyclase activator 1d. (186 aa)
	Htr2a	5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a. (453 aa)
	dab2	DAB adaptor protein 2. (741 aa)
	abcg4	ATP-binding cassette, sub-family G (WHITE), member 4a. (630 aa)
	nr1h4	Nuclear receptor subfamily 1, group H, member 4. (476 aa)
	zbtb20	Zinc finger and BTB domain containing 20. (683 aa)
	LOC109513614	ABC transporter domain-containing protein. (647 aa)
	ddb1	Damage-specific DNA binding protein 1. (1093 aa)
	nr1h3	Nuclear receptor subfamily 1, group H, member 3. (462 aa)
	LOC109531321	Nuclear receptor subfamily 1, group D, member 4a. (571 aa)
	PPARG	Peroxisome proliferator activated receptor gamma. (575 aa)
	LOC109508095	Uncharacterized protein. (109 aa)
	ENSHCOP00000018192	Si:dkey-6n21.13; Belongs to the G-protein coupled receptor 1 family. (331 aa)
	LOC109508105	Uncharacterized protein. (107 aa)
	prxl2c	Peroxiredoxin like 2C. (224 aa)
	podn	Podocan. (587 aa)
	LOC109517754	Nuclear receptor subfamily 1, group H, member 5. (488 aa)
	ENSHCOP00000019285	Deacetylase sirtuin-type domain-containing protein. (166 aa)
	ENSHCOP00000019306	Sirtuin 1. (369 aa)
	ENSHCOP00000019657	Si:ch211-103a14.5. (124 aa)
	LOC109515764	Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins [...] (163 aa)
	lpgat1	Lysophosphatidylglycerol acyltransferase 1. (388 aa)
	ptgs2	Prostaglandin-endoperoxide synthase 2b. (608 aa)
	rusc1	RUN and SH3 domain containing 1. (528 aa)
	igf2	Insulin-like growth factor 2b. (216 aa)
	bend3	BEN domain containing 3. (814 aa)
	guca1b	Guanylate cyclase activator 1B. (197 aa)
	LOC109513534	Uncharacterized protein. (259 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000013250	ENSHCOP00000014775	ENSHCOP00000013250	ENSHCOP00000014775	Uncharacterized protein.	Insulin-like growth factor 1.	0.591
ENSHCOP00000014775	ENSHCOP00000013250	ENSHCOP00000014775	ENSHCOP00000013250	Insulin-like growth factor 1.	Uncharacterized protein.	0.591
ENSHCOP00000014775	LOC109513432	ENSHCOP00000014775	ENSHCOP00000012063	Insulin-like growth factor 1.	Interleukin-1.	0.555
ENSHCOP00000014775	LOC109515764	ENSHCOP00000014775	ENSHCOP00000019908	Insulin-like growth factor 1.	Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins [...]	0.414
ENSHCOP00000014775	LOC109517974	ENSHCOP00000014775	ENSHCOP00000012707	Insulin-like growth factor 1.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.414
ENSHCOP00000014775	igf2	ENSHCOP00000014775	ENSHCOP00000021870	Insulin-like growth factor 1.	Insulin-like growth factor 2b.	0.772
ENSHCOP00000014775	ppargc1a	ENSHCOP00000014775	ENSHCOP00000011947	Insulin-like growth factor 1.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.471
ENSHCOP00000019285	ppargc1a	ENSHCOP00000019285	ENSHCOP00000011947	Deacetylase sirtuin-type domain-containing protein.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.603
ENSHCOP00000019306	ppargc1a	ENSHCOP00000019306	ENSHCOP00000011947	Sirtuin 1.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.603
ENSHCOP00000019657	guca1b	ENSHCOP00000019657	ENSHCOP00000023439	Si:ch211-103a14.5.	Guanylate cyclase activator 1B.	0.702
LOC109510814	abcg4	ENSHCOP00000023659	ENSHCOP00000001164	ABC transporter domain-containing protein.	ATP-binding cassette, sub-family G (WHITE), member 4a.	0.900
LOC109510814	apoa4	ENSHCOP00000023659	ENSHCOP00000011146	ABC transporter domain-containing protein.	Uncharacterized protein.	0.543
LOC109512469	guca1a	ENSHCOP00000003003	ENSHCOP00000026528	Guanylate cyclase activator 1d.	Guanylate cyclase activator 1A.	0.487
LOC109513432	ENSHCOP00000014775	ENSHCOP00000012063	ENSHCOP00000014775	Interleukin-1.	Insulin-like growth factor 1.	0.555
LOC109513432	ptgs2	ENSHCOP00000012063	ENSHCOP00000020518	Interleukin-1.	Prostaglandin-endoperoxide synthase 2b.	0.828
LOC109513534	apoa4	ENSHCOP00000023595	ENSHCOP00000011146	Uncharacterized protein.	Uncharacterized protein.	0.701
LOC109513614	apoa4	ENSHCOP00000007651	ENSHCOP00000011146	ABC transporter domain-containing protein.	Uncharacterized protein.	0.543
LOC109515764	ENSHCOP00000014775	ENSHCOP00000019908	ENSHCOP00000014775	Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins [...]	Insulin-like growth factor 1.	0.414
LOC109517754	ppargc1a	ENSHCOP00000018947	ENSHCOP00000011947	Nuclear receptor subfamily 1, group H, member 5.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.868
LOC109517974	ENSHCOP00000014775	ENSHCOP00000012707	ENSHCOP00000014775	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Insulin-like growth factor 1.	0.414