19 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sirt2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (372 aa)
	sirt4	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (308 aa)
	ehhadh	Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (713 aa)
	LOC109521238	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (306 aa)
	ENSHCOP00000019285	Deacetylase sirtuin-type domain-containing protein. (166 aa)
	cryl1	Crystallin, lambda 1. (312 aa)
	ENSHCOP00000019306	Sirtuin 1. (369 aa)
	LOC109528452	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a; Belongs to the enoyl-CoA hydratase/isomerase family. (736 aa)
	LOC109518149	Zgc:56585; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (264 aa)
	sirt6	Sirtuin 6. (347 aa)
	uxs1	UDP-glucuronate decarboxylase 1. (398 aa)
	hadh	Hydroxyacyl-CoA dehydrogenase. (309 aa)
	LOC109523155	Sirtuin 1. (657 aa)
	sirt3	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (348 aa)
	LOC109531260	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (412 aa)
	sirt5	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (283 aa)
	LOC109528184	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
	sirt7	Sirtuin 7. (364 aa)
	ENSHCOP00000012466	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (233 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000012466	cryl1	ENSHCOP00000012466	ENSHCOP00000026827	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	Crystallin, lambda 1.	0.532
ENSHCOP00000012466	hadh	ENSHCOP00000012466	ENSHCOP00000003081	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	Hydroxyacyl-CoA dehydrogenase.	0.756
ENSHCOP00000019285	LOC109531260	ENSHCOP00000019285	ENSHCOP00000005259	Deacetylase sirtuin-type domain-containing protein.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.514
ENSHCOP00000019285	sirt2	ENSHCOP00000019285	ENSHCOP00000013742	Deacetylase sirtuin-type domain-containing protein.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.455
ENSHCOP00000019285	sirt3	ENSHCOP00000019285	ENSHCOP00000004832	Deacetylase sirtuin-type domain-containing protein.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.514
ENSHCOP00000019285	sirt6	ENSHCOP00000019285	ENSHCOP00000000544	Deacetylase sirtuin-type domain-containing protein.	Sirtuin 6.	0.430
ENSHCOP00000019285	sirt7	ENSHCOP00000019285	ENSHCOP00000012046	Deacetylase sirtuin-type domain-containing protein.	Sirtuin 7.	0.460
ENSHCOP00000019306	LOC109531260	ENSHCOP00000019306	ENSHCOP00000005259	Sirtuin 1.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.571
ENSHCOP00000019306	sirt2	ENSHCOP00000019306	ENSHCOP00000013742	Sirtuin 1.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.511
ENSHCOP00000019306	sirt3	ENSHCOP00000019306	ENSHCOP00000004832	Sirtuin 1.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.566
ENSHCOP00000019306	sirt4	ENSHCOP00000019306	ENSHCOP00000014164	Sirtuin 1.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.479
ENSHCOP00000019306	sirt6	ENSHCOP00000019306	ENSHCOP00000000544	Sirtuin 1.	Sirtuin 6.	0.430
ENSHCOP00000019306	sirt7	ENSHCOP00000019306	ENSHCOP00000012046	Sirtuin 1.	Sirtuin 7.	0.460
LOC109521238	LOC109531260	ENSHCOP00000016741	ENSHCOP00000005259	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.547
LOC109521238	sirt2	ENSHCOP00000016741	ENSHCOP00000013742	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.623
LOC109521238	sirt3	ENSHCOP00000016741	ENSHCOP00000004832	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.576
LOC109521238	sirt4	ENSHCOP00000016741	ENSHCOP00000014164	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.480
LOC109521238	sirt6	ENSHCOP00000016741	ENSHCOP00000000544	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Sirtuin 6.	0.824
LOC109521238	sirt7	ENSHCOP00000016741	ENSHCOP00000012046	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	Sirtuin 7.	0.620
LOC109523155	LOC109531260	ENSHCOP00000003219	ENSHCOP00000005259	Sirtuin 1.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.568