82 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109520706	Uncharacterized protein. (237 aa)
	noc2l	NOC2-like nucleolar associated transcriptional repressor. (760 aa)
	LOC109527038	ATPase family AAA domain containing 5a. (1619 aa)
	plaur	Lymphocyte antigen 6 family member M6. (206 aa)
	ptpmt1	Protein tyrosine phosphatase mitochondrial 1. (184 aa)
	ndufs3	NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (259 aa)
	uri1	URI1 prefoldin like chaperone. (490 aa)
	trap1	TNF receptor-associated protein 1. (719 aa)
	LOC109513573	Tyrosine-protein kinase. (538 aa)
	wfs1	Uncharacterized protein. (382 aa)
	ENSHCOP00000008605	F-box domain-containing protein. (729 aa)
	nck1	Cytoplasmic protein. (393 aa)
	msx1	Muscle segment homeobox 1a. (286 aa)
	ENSHCOP00000009898	Ventral anterior homeobox 2. (270 aa)
	ENSHCOP00000009932	Tripartite motif containing 32. (638 aa)
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (839 aa)
	LOC109512183	MCL1 apoptosis regulator, BCL2 family member b. (289 aa)
	eif2ak3	Eukaryotic translation initiation factor 2-alpha kinase 3. (1106 aa)
	LOC109517508	cAMP responsive element binding protein 3-like 3 like. (497 aa)
	bad	Uncharacterized protein. (173 aa)
	gsdme	Gasdermin Eb. (406 aa)
	ENSHCOP00000020224	Clusterin; Belongs to the clusterin family. (439 aa)
	ptgs2	Prostaglandin-endoperoxide synthase 2b. (608 aa)
	hyou1	Hypoxia up-regulated 1. (973 aa)
	bcl2l1	BCL2 like 1. (225 aa)
	vax1	Ventral anterior homeobox 1. (287 aa)
	LOC109516522	Uncharacterized protein. (727 aa)
	usp47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1363 aa)
	skil	SKI-like proto-oncogene a. (685 aa)
	LOC109521498	Cylindromatosis (turban tumor syndrome), b. (711 aa)
	ENSHCOP00000002481	BCL2 apoptosis regulator b. (221 aa)
	ENSHCOP00000002506	BCL2 apoptosis regulator b. (225 aa)
	LOC109523155	Sirtuin 1. (657 aa)
	LOC109512014	Uncharacterized protein. (471 aa)
	ENSHCOP00000013336	Protein kinase domain-containing protein. (472 aa)
	ENSHCOP00000013347	Uncharacterized protein. (1158 aa)
	LOC109516237	Muscle segment homeobox 3. (253 aa)
	rnf2	Ring finger protein 2. (344 aa)
	cdkn2d	Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (162 aa)
	ivns1abp	Influenza virus NS1A binding protein a. (650 aa)
	LOC109525219	NK3 homeobox 1. (189 aa)
	pdx1	Pancreatic and duodenal homeobox 1. (250 aa)
	LOC109528315	Uncharacterized protein. (526 aa)
	SNAI2	Snail family transcriptional repressor 2. (249 aa)
	tpt1	Tumor protein, translationally-controlled 1; Belongs to the TCTP family. (204 aa)
	marchf7	Membrane-associated ring finger (C3HC4) 7. (787 aa)
	ENSHCOP00000016231	Si:dkey-63b1.1; Belongs to the G-protein coupled receptor 1 family. (345 aa)
	ENSHCOP00000016349	Nuclear protein 1a. (76 aa)
	LOC109514032	BCL2 like 10. (200 aa)
	ENSHCOP00000016763	Uncharacterized protein. (142 aa)
	flcn	Folliculin. (550 aa)
	hells	Helicase, lymphoid specific. (713 aa)
	nme5	NME/NM23 family member 5; Belongs to the NDK family. (254 aa)
	BDKRB2	Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (384 aa)
	LOC109514592	Tyrosine-protein phosphatase non-receptor type. (368 aa)
	nck2	NCK adaptor protein 2a. (189 aa)
	bag5	BCL2 associated athanogene 5. (579 aa)
	ackr3	Atypical chemokine receptor 3a; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	ENSHCOP00000019285	Deacetylase sirtuin-type domain-containing protein. (166 aa)
	ENSHCOP00000019306	Sirtuin 1. (369 aa)
	src	Tyrosine-protein kinase. (543 aa)
	NDUFA13	NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
	ddit3	DNA-damage-inducible transcript 3. (295 aa)
	cyld	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (771 aa)
	txndc12	Thioredoxin domain containing 12 (endoplasmic reticulum). (207 aa)
	clu	Clusterin; Belongs to the clusterin family. (461 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (598 aa)
	LOC109526882	Tyrosine-protein phosphatase non-receptor type. (406 aa)
	hspb1	Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family. (201 aa)
	ENSHCOP00000023517	Uncharacterized protein. (233 aa)
	LOC109511429	Wolfram syndrome 1a (wolframin). (742 aa)
	xbp1	X-box binding protein 1. (262 aa)
	LOC109518769	NME/NM23 family member 5. (208 aa)
	ENSHCOP00000026411	Uncharacterized protein. (408 aa)
	bax	BCL2 associated X, apoptosis regulator a. (255 aa)
	LOC109509473	Uncharacterized protein. (530 aa)
	ENSHCOP00000027903	annotation not available (76 aa)
	ptpn2	Tyrosine-protein phosphatase non-receptor type. (411 aa)
	LOC109519212	Uncharacterized protein. (175 aa)
	nupr1	Nuclear protein 1b. (74 aa)
	tmem161a	Transmembrane protein 161A. (487 aa)
	Triap1	TP53 regulated inhibitor of apoptosis 1. (83 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDKRB2	ENSHCOP00000016231	ENSHCOP00000017538	ENSHCOP00000016231	Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family.	Si:dkey-63b1.1; Belongs to the G-protein coupled receptor 1 family.	0.901
ENSHCOP00000002481	LOC109514032	ENSHCOP00000002481	ENSHCOP00000016524	BCL2 apoptosis regulator b.	BCL2 like 10.	0.469
ENSHCOP00000002481	bad	ENSHCOP00000002481	ENSHCOP00000010908	BCL2 apoptosis regulator b.	Uncharacterized protein.	0.874
ENSHCOP00000002481	bax	ENSHCOP00000002481	ENSHCOP00000026539	BCL2 apoptosis regulator b.	BCL2 associated X, apoptosis regulator a.	0.935
ENSHCOP00000002481	bcl2l1	ENSHCOP00000002481	ENSHCOP00000021075	BCL2 apoptosis regulator b.	BCL2 like 1.	0.806
ENSHCOP00000002506	LOC109514032	ENSHCOP00000002506	ENSHCOP00000016524	BCL2 apoptosis regulator b.	BCL2 like 10.	0.469
ENSHCOP00000002506	bad	ENSHCOP00000002506	ENSHCOP00000010908	BCL2 apoptosis regulator b.	Uncharacterized protein.	0.986
ENSHCOP00000002506	bax	ENSHCOP00000002506	ENSHCOP00000026539	BCL2 apoptosis regulator b.	BCL2 associated X, apoptosis regulator a.	0.993
ENSHCOP00000002506	bcl2l1	ENSHCOP00000002506	ENSHCOP00000021075	BCL2 apoptosis regulator b.	BCL2 like 1.	0.959
ENSHCOP00000002506	ddit3	ENSHCOP00000002506	ENSHCOP00000000296	BCL2 apoptosis regulator b.	DNA-damage-inducible transcript 3.	0.932
ENSHCOP00000008605	ENSHCOP00000026411	ENSHCOP00000008605	ENSHCOP00000026411	F-box domain-containing protein.	Uncharacterized protein.	0.636
ENSHCOP00000008605	LOC109527038	ENSHCOP00000008605	ENSHCOP00000004580	F-box domain-containing protein.	ATPase family AAA domain containing 5a.	0.636
ENSHCOP00000013336	ENSHCOP00000013347	ENSHCOP00000013336	ENSHCOP00000013347	Protein kinase domain-containing protein.	Uncharacterized protein.	0.945
ENSHCOP00000013347	ENSHCOP00000013336	ENSHCOP00000013347	ENSHCOP00000013336	Uncharacterized protein.	Protein kinase domain-containing protein.	0.945
ENSHCOP00000016231	BDKRB2	ENSHCOP00000016231	ENSHCOP00000017538	Si:dkey-63b1.1; Belongs to the G-protein coupled receptor 1 family.	Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family.	0.901
ENSHCOP00000019285	kdm1a	ENSHCOP00000019285	ENSHCOP00000010393	Deacetylase sirtuin-type domain-containing protein.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.442
ENSHCOP00000019306	kdm1a	ENSHCOP00000019306	ENSHCOP00000010393	Sirtuin 1.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.442
ENSHCOP00000023517	LOC109512183	ENSHCOP00000023517	ENSHCOP00000010485	Uncharacterized protein.	MCL1 apoptosis regulator, BCL2 family member b.	0.904
ENSHCOP00000023517	bad	ENSHCOP00000023517	ENSHCOP00000010908	Uncharacterized protein.	Uncharacterized protein.	0.709
ENSHCOP00000023517	bax	ENSHCOP00000023517	ENSHCOP00000026539	Uncharacterized protein.	BCL2 associated X, apoptosis regulator a.	0.883