(31 nodes) SCF ubiquitin ligase complex network (Hippocampus comes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	skp2	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (425 aa)
	usp47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1363 aa)
	fbxl17	F-box and leucine-rich repeat protein 17. (607 aa)
	fbxw5	F-box and WD repeat domain containing 5. (607 aa)
	fbxl6	F-box domain-containing protein. (550 aa)
	tmem183a	Transmembrane protein 183A. (359 aa)
	fbxl3	F-box and leucine-rich repeat protein 3a. (435 aa)
	ENSHCOP00000008605	F-box domain-containing protein. (729 aa)
	fbxo25	F-box protein 25. (354 aa)
	fbxl5	F-box and leucine-rich repeat protein 5. (690 aa)
	Fbxl7	Si:dkey-192l18.9. (425 aa)
	fbxl22	F-box and leucine-rich repeat protein 22. (229 aa)
	fbxo4	F-box protein 4. (364 aa)
	ENSHCOP00000011234	Uncharacterized protein. (199 aa)
	rbx1	Ring-box 1, E3 ubiquitin protein ligase. (181 aa)
	zc3hc1	Zinc finger, C3HC-type containing 1. (479 aa)
	fbxw11	F-box and WD repeat domain containing 11b. (527 aa)
	FBXL14	F-box and leucine rich repeat protein 14. (416 aa)
	fbxo9	F-box protein 9. (400 aa)
	fbxo32	F-box protein 32. (354 aa)
	LOC109513724	Uncharacterized protein. (831 aa)
	LOC109514645	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (77 aa)
	fbxo42	F-box protein 42. (704 aa)
	fbxo31	F-box protein 31. (538 aa)
	LOC109526763	F-box and leucine-rich repeat protein 14a. (403 aa)
	LOC109526808	Leucine rich repeat containing 29. (626 aa)
	fbxo33	F-box protein 33. (490 aa)
	ENSHCOP00000027605	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	Fbxl15	F-box and leucine-rich repeat protein 15. (284 aa)
	fbxo41	F-box protein 41. (818 aa)
	LOC109524622	F-box domain-containing protein. (431 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000008605	fbxo4	ENSHCOP00000008605	ENSHCOP00000010965	F-box domain-containing protein.	F-box protein 4.	0.407
ENSHCOP00000008605	fbxo9	ENSHCOP00000008605	ENSHCOP00000012743	F-box domain-containing protein.	F-box protein 9.	0.407
ENSHCOP00000008605	rbx1	ENSHCOP00000008605	ENSHCOP00000011377	F-box domain-containing protein.	Ring-box 1, E3 ubiquitin protein ligase.	0.664
ENSHCOP00000011234	fbxl17	ENSHCOP00000011234	ENSHCOP00000002308	Uncharacterized protein.	F-box and leucine-rich repeat protein 17.	0.900
ENSHCOP00000011234	rbx1	ENSHCOP00000011234	ENSHCOP00000011377	Uncharacterized protein.	Ring-box 1, E3 ubiquitin protein ligase.	0.772
ENSHCOP00000011234	skp2	ENSHCOP00000011234	ENSHCOP00000001545	Uncharacterized protein.	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.	0.547
ENSHCOP00000027605	rbx1	ENSHCOP00000027605	ENSHCOP00000011377	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Ring-box 1, E3 ubiquitin protein ligase.	0.568
ENSHCOP00000027605	skp2	ENSHCOP00000027605	ENSHCOP00000001545	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.	0.965
FBXL14	fbxo25	ENSHCOP00000011930	ENSHCOP00000009478	F-box and leucine rich repeat protein 14.	F-box protein 25.	0.463
FBXL14	fbxo33	ENSHCOP00000011930	ENSHCOP00000023865	F-box and leucine rich repeat protein 14.	F-box protein 33.	0.407
FBXL14	fbxo9	ENSHCOP00000011930	ENSHCOP00000012743	F-box and leucine rich repeat protein 14.	F-box protein 9.	0.405
FBXL14	fbxw5	ENSHCOP00000011930	ENSHCOP00000002521	F-box and leucine rich repeat protein 14.	F-box and WD repeat domain containing 5.	0.456
FBXL14	rbx1	ENSHCOP00000011930	ENSHCOP00000011377	F-box and leucine rich repeat protein 14.	Ring-box 1, E3 ubiquitin protein ligase.	0.761
FBXL14	skp2	ENSHCOP00000011930	ENSHCOP00000001545	F-box and leucine rich repeat protein 14.	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.	0.530
Fbxl15	fbxo33	ENSHCOP00000027691	ENSHCOP00000023865	F-box and leucine-rich repeat protein 15.	F-box protein 33.	0.586
Fbxl15	rbx1	ENSHCOP00000027691	ENSHCOP00000011377	F-box and leucine-rich repeat protein 15.	Ring-box 1, E3 ubiquitin protein ligase.	0.772
Fbxl15	skp2	ENSHCOP00000027691	ENSHCOP00000001545	F-box and leucine-rich repeat protein 15.	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.	0.561
Fbxl7	fbxo33	ENSHCOP00000010090	ENSHCOP00000023865	Si:dkey-192l18.9.	F-box protein 33.	0.407
Fbxl7	rbx1	ENSHCOP00000010090	ENSHCOP00000011377	Si:dkey-192l18.9.	Ring-box 1, E3 ubiquitin protein ligase.	0.824
Fbxl7	skp2	ENSHCOP00000010090	ENSHCOP00000001545	Si:dkey-192l18.9.	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.	0.447