(8 nodes) Toll-like receptor network (Hippocampus comes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109531639	Toll-like receptor 21. (982 aa)
	LOC109514841	Uncharacterized protein. (789 aa)
	LOC109512204	Toll-like receptor 18; Belongs to the Toll-like receptor family. (858 aa)
	LOC109524722	Toll-like receptor 22; Belongs to the Toll-like receptor family. (961 aa)
	LOC109513611	TIR domain-containing protein; Belongs to the Toll-like receptor family. (821 aa)
	TLR5	Toll like receptor 5; Belongs to the Toll-like receptor family. (883 aa)
	tril	TLR4 interactor with leucine-rich repeats. (768 aa)
	tlr3	Toll-like receptor 3; Belongs to the Toll-like receptor family. (910 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC109512204	LOC109513611	ENSHCOP00000024228	ENSHCOP00000021914	Toll-like receptor 18; Belongs to the Toll-like receptor family.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.900
LOC109512204	tlr3	ENSHCOP00000024228	ENSHCOP00000005408	Toll-like receptor 18; Belongs to the Toll-like receptor family.	Toll-like receptor 3; Belongs to the Toll-like receptor family.	0.411
LOC109513611	LOC109512204	ENSHCOP00000021914	ENSHCOP00000024228	TIR domain-containing protein; Belongs to the Toll-like receptor family.	Toll-like receptor 18; Belongs to the Toll-like receptor family.	0.900
LOC109513611	tlr3	ENSHCOP00000021914	ENSHCOP00000005408	TIR domain-containing protein; Belongs to the Toll-like receptor family.	Toll-like receptor 3; Belongs to the Toll-like receptor family.	0.411
tlr3	LOC109512204	ENSHCOP00000005408	ENSHCOP00000024228	Toll-like receptor 3; Belongs to the Toll-like receptor family.	Toll-like receptor 18; Belongs to the Toll-like receptor family.	0.411
tlr3	LOC109513611	ENSHCOP00000005408	ENSHCOP00000021914	Toll-like receptor 3; Belongs to the Toll-like receptor family.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.411