9 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	sirt4	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (308 aa)
	sirt2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (372 aa)
	sirt5	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (283 aa)
	LOC109531260	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (412 aa)
	sirt3	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (348 aa)
	LOC109523155	Sirtuin 1. (657 aa)
	ENSHCOP00000019306	Sirtuin 1. (369 aa)
	ENSHCOP00000019285	Deacetylase sirtuin-type domain-containing protein. (166 aa)
	LOC109521238	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (306 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000019285	LOC109531260	ENSHCOP00000019285	ENSHCOP00000005259	Deacetylase sirtuin-type domain-containing protein.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.514
ENSHCOP00000019285	sirt2	ENSHCOP00000019285	ENSHCOP00000013742	Deacetylase sirtuin-type domain-containing protein.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.455
ENSHCOP00000019285	sirt3	ENSHCOP00000019285	ENSHCOP00000004832	Deacetylase sirtuin-type domain-containing protein.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.514
ENSHCOP00000019306	LOC109531260	ENSHCOP00000019306	ENSHCOP00000005259	Sirtuin 1.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.571
ENSHCOP00000019306	sirt2	ENSHCOP00000019306	ENSHCOP00000013742	Sirtuin 1.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.511
ENSHCOP00000019306	sirt3	ENSHCOP00000019306	ENSHCOP00000004832	Sirtuin 1.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.566
ENSHCOP00000019306	sirt4	ENSHCOP00000019306	ENSHCOP00000014164	Sirtuin 1.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.479
LOC109521238	LOC109531260	ENSHCOP00000016741	ENSHCOP00000005259	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.547
LOC109521238	sirt2	ENSHCOP00000016741	ENSHCOP00000013742	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.623
LOC109521238	sirt3	ENSHCOP00000016741	ENSHCOP00000004832	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.576
LOC109521238	sirt4	ENSHCOP00000016741	ENSHCOP00000014164	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.480
LOC109523155	LOC109531260	ENSHCOP00000003219	ENSHCOP00000005259	Sirtuin 1.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.568
LOC109523155	sirt2	ENSHCOP00000003219	ENSHCOP00000013742	Sirtuin 1.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.503
LOC109523155	sirt3	ENSHCOP00000003219	ENSHCOP00000004832	Sirtuin 1.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.554
LOC109523155	sirt4	ENSHCOP00000003219	ENSHCOP00000014164	Sirtuin 1.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.471
LOC109531260	ENSHCOP00000019285	ENSHCOP00000005259	ENSHCOP00000019285	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	Deacetylase sirtuin-type domain-containing protein.	0.514
LOC109531260	ENSHCOP00000019306	ENSHCOP00000005259	ENSHCOP00000019306	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	Sirtuin 1.	0.571
LOC109531260	LOC109521238	ENSHCOP00000005259	ENSHCOP00000016741	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.547
LOC109531260	LOC109523155	ENSHCOP00000005259	ENSHCOP00000003219	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	Sirtuin 1.	0.568
LOC109531260	sirt4	ENSHCOP00000005259	ENSHCOP00000014164	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.540