17 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	LOC109521238	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (306 aa)
	ENSHCOP00000019285	Deacetylase sirtuin-type domain-containing protein. (166 aa)
	ENSHCOP00000019306	Sirtuin 1. (369 aa)
	ilvbl	IlvB (bacterial acetolactate synthase)-like; Belongs to the TPP enzyme family. (619 aa)
	etfa	Electron transfer flavoprotein subunit alpha. (344 aa)
	sirt4	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (308 aa)
	LOC109525977	Nicotinamide nucleotide transhydrogenase 2. (1071 aa)
	LOC109517090	Nicotinamide nucleotide transhydrogenase. (1085 aa)
	LOC109523155	Sirtuin 1. (657 aa)
	hacl1	2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (459 aa)
	dhps	Deoxyhypusine synthase. (360 aa)
	sirt3	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (348 aa)
	LOC109531260	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (412 aa)
	sirt2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (372 aa)
	sirt7	Sirtuin 7. (364 aa)
	sirt5	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (283 aa)
	sirt6	Sirtuin 6. (347 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000019285	LOC109531260	ENSHCOP00000019285	ENSHCOP00000005259	Deacetylase sirtuin-type domain-containing protein.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.514
ENSHCOP00000019285	sirt2	ENSHCOP00000019285	ENSHCOP00000013742	Deacetylase sirtuin-type domain-containing protein.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.455
ENSHCOP00000019285	sirt3	ENSHCOP00000019285	ENSHCOP00000004832	Deacetylase sirtuin-type domain-containing protein.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.514
ENSHCOP00000019285	sirt6	ENSHCOP00000019285	ENSHCOP00000000544	Deacetylase sirtuin-type domain-containing protein.	Sirtuin 6.	0.430
ENSHCOP00000019285	sirt7	ENSHCOP00000019285	ENSHCOP00000012046	Deacetylase sirtuin-type domain-containing protein.	Sirtuin 7.	0.460
ENSHCOP00000019306	LOC109531260	ENSHCOP00000019306	ENSHCOP00000005259	Sirtuin 1.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.571
ENSHCOP00000019306	sirt2	ENSHCOP00000019306	ENSHCOP00000013742	Sirtuin 1.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.511
ENSHCOP00000019306	sirt3	ENSHCOP00000019306	ENSHCOP00000004832	Sirtuin 1.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.566
ENSHCOP00000019306	sirt4	ENSHCOP00000019306	ENSHCOP00000014164	Sirtuin 1.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.479
ENSHCOP00000019306	sirt6	ENSHCOP00000019306	ENSHCOP00000000544	Sirtuin 1.	Sirtuin 6.	0.430
ENSHCOP00000019306	sirt7	ENSHCOP00000019306	ENSHCOP00000012046	Sirtuin 1.	Sirtuin 7.	0.460
LOC109517090	LOC109521238	ENSHCOP00000002218	ENSHCOP00000016741	Nicotinamide nucleotide transhydrogenase.	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.900
LOC109517090	LOC109523155	ENSHCOP00000002218	ENSHCOP00000003219	Nicotinamide nucleotide transhydrogenase.	Sirtuin 1.	0.900
LOC109517090	LOC109525977	ENSHCOP00000002218	ENSHCOP00000000912	Nicotinamide nucleotide transhydrogenase.	Nicotinamide nucleotide transhydrogenase 2.	0.901
LOC109517090	LOC109531260	ENSHCOP00000002218	ENSHCOP00000005259	Nicotinamide nucleotide transhydrogenase.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.901
LOC109517090	sirt2	ENSHCOP00000002218	ENSHCOP00000013742	Nicotinamide nucleotide transhydrogenase.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.900
LOC109517090	sirt3	ENSHCOP00000002218	ENSHCOP00000004832	Nicotinamide nucleotide transhydrogenase.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.901
LOC109517090	sirt4	ENSHCOP00000002218	ENSHCOP00000014164	Nicotinamide nucleotide transhydrogenase.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.900
LOC109517090	sirt5	ENSHCOP00000002218	ENSHCOP00000006432	Nicotinamide nucleotide transhydrogenase.	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.900
LOC109517090	sirt7	ENSHCOP00000002218	ENSHCOP00000012046	Nicotinamide nucleotide transhydrogenase.	Sirtuin 7.	0.903