68 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	vcp	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	Polk	Polymerase (DNA directed) kappa. (396 aa)
	ENSHCOP00000011398	Uncharacterized protein. (533 aa)
	rfc4	Replication factor C (activator 1) 4. (331 aa)
	pole2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (521 aa)
	sprtn	SprT-like N-terminal domain. (405 aa)
	LOC109517068	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (572 aa)
	ENSHCOP00000009735	Tripartite motif containing 25, like. (586 aa)
	ubc	Uncharacterized protein. (989 aa)
	LOC109531101	FinTRIM family, member 82. (578 aa)
	pold3	Polymerase (DNA-directed), delta 3, accessory subunit. (437 aa)
	LOC109531293	Si:dkey-24l11.2. (667 aa)
	LOC109526212	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (532 aa)
	ubb	Ubiquitin B. (281 aa)
	ENSHCOP00000007719	Ubiquitin-like domain-containing protein. (106 aa)
	ENSHCOP00000007515	Uncharacterized protein. (89 aa)
	pclaf	PCNA clamp associated factor. (121 aa)
	rev3l	REV3 like, DNA directed polymerase zeta catalytic subunit. (2836 aa)
	rpa2	Replication protein A2. (314 aa)
	LOC109527038	ATPase family AAA domain containing 5a. (1619 aa)
	pole3	Polymerase (DNA directed), epsilon 3 (p17 subunit). (148 aa)
	ufd1	Ubiquitin recognition factor in ER associated degradation 1. (310 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	LOC109509897	FinTRIM family, member 14-like. (510 aa)
	rev1	REV1 DNA directed polymerase. (809 aa)
	usp10	Ubiquitin carboxyl-terminal hydrolase. (871 aa)
	LOC109511914	Uncharacterized protein. (398 aa)
	mad2l2	Mitotic arrest deficient 2 like 2. (210 aa)
	rfc1	Replication factor C subunit 1. (1130 aa)
	meiob	Methionine sulfoxide reductase B1b. (439 aa)
	spata5l1	Spermatogenesis associated 5-like 1. (715 aa)
	ENSHCOP00000028059	Uncharacterized protein. (127 aa)
	polh	Polymerase (DNA directed), eta. (483 aa)
	ENSHCOP00000026411	Uncharacterized protein. (408 aa)
	pold2	Polymerase (DNA directed), delta 2, regulatory subunit. (470 aa)
	rpa3	Replication protein A3. (127 aa)
	pold4	Si:dkey-28b4.7. (106 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (611 aa)
	pold1	DNA polymerase. (1105 aa)
	ENSHCOP00000024677	FinTRIM family, member 67. (463 aa)
	rfc2	Replication factor C (activator 1) 2. (244 aa)
	kxd1	KxDL motif containing 1. (185 aa)
	LOC109511055	Uncharacterized protein. (614 aa)
	LOC109520855	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (527 aa)
	rfc3	Replication factor C (activator 1) 3. (356 aa)
	LOC109508472	Ubiquitin specific peptidase 43b; Belongs to the peptidase C19 family. (1084 aa)
	pole	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2282 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	rchy1	Ring finger and CHY zinc finger domain containing 1. (269 aa)
	SPATA5	Spermatogenesis associated 5. (887 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	LOC109512331	UmuC domain-containing protein. (184 aa)
	LOC109532275	SCY domain-containing protein. (126 aa)
	Pole4	CBFD_NFYB_HMF domain-containing protein. (128 aa)
	rfc5	Replication factor C (activator 1) 5. (335 aa)
	LOC109516624	Bloodthirsty-related gene family, member 26. (575 aa)
	poli	Polymerase (DNA directed) iota. (621 aa)
	LOC109519926	Uncharacterized protein. (570 aa)
	ENSHCOP00000016056	B30.2/SPRY domain-containing protein. (226 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	ENSHCOP00000015336	Si:dkey-46i9.6. (243 aa)
	nploc4	NPL4 homolog, ubiquitin recognition factor. (625 aa)
	LOC109516488	Si:dkey-46i9.6. (547 aa)
	LOC109511189	Ubiquitin specific peptidase 43a; Belongs to the peptidase C19 family. (1036 aa)
	ENSHCOP00000014489	Ubiquitin carboxyl-terminal hydrolase. (487 aa)
	LOC109516490	Bloodthirsty-related gene family, member 12. (584 aa)
	ENSHCOP00000012645	Uncharacterized protein. (460 aa)
	LOC109519350	Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1255 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000007515	ENSHCOP00000014489	ENSHCOP00000007515	ENSHCOP00000014489	Uncharacterized protein.	Ubiquitin carboxyl-terminal hydrolase.	0.401
ENSHCOP00000007515	ENSHCOP00000026411	ENSHCOP00000007515	ENSHCOP00000026411	Uncharacterized protein.	Uncharacterized protein.	0.926
ENSHCOP00000007515	ENSHCOP00000028059	ENSHCOP00000007515	ENSHCOP00000028059	Uncharacterized protein.	Uncharacterized protein.	0.728
ENSHCOP00000007515	LOC109508472	ENSHCOP00000007515	ENSHCOP00000021825	Uncharacterized protein.	Ubiquitin specific peptidase 43b; Belongs to the peptidase C19 family.	0.401
ENSHCOP00000007515	LOC109511189	ENSHCOP00000007515	ENSHCOP00000014621	Uncharacterized protein.	Ubiquitin specific peptidase 43a; Belongs to the peptidase C19 family.	0.401
ENSHCOP00000007515	LOC109512331	ENSHCOP00000007515	ENSHCOP00000018206	Uncharacterized protein.	UmuC domain-containing protein.	0.596
ENSHCOP00000007515	LOC109517068	ENSHCOP00000007515	ENSHCOP00000009787	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.742
ENSHCOP00000007515	LOC109519350	ENSHCOP00000007515	ENSHCOP00000012544	Uncharacterized protein.	Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family.	0.401
ENSHCOP00000007515	LOC109527038	ENSHCOP00000007515	ENSHCOP00000004580	Uncharacterized protein.	ATPase family AAA domain containing 5a.	0.926
ENSHCOP00000007515	LOC109531293	ENSHCOP00000007515	ENSHCOP00000009299	Uncharacterized protein.	Si:dkey-24l11.2.	0.483
ENSHCOP00000007515	LOC109532275	ENSHCOP00000007515	ENSHCOP00000018064	Uncharacterized protein.	SCY domain-containing protein.	0.599
ENSHCOP00000007515	Pole4	ENSHCOP00000007515	ENSHCOP00000018062	Uncharacterized protein.	CBFD_NFYB_HMF domain-containing protein.	0.666
ENSHCOP00000007515	Polk	ENSHCOP00000007515	ENSHCOP00000011993	Uncharacterized protein.	Polymerase (DNA directed) kappa.	0.675
ENSHCOP00000007515	SPATA5	ENSHCOP00000007515	ENSHCOP00000019051	Uncharacterized protein.	Spermatogenesis associated 5.	0.486
ENSHCOP00000007515	mad2l2	ENSHCOP00000007515	ENSHCOP00000001724	Uncharacterized protein.	Mitotic arrest deficient 2 like 2.	0.669
ENSHCOP00000007515	meiob	ENSHCOP00000007515	ENSHCOP00000001422	Uncharacterized protein.	Methionine sulfoxide reductase B1b.	0.702
ENSHCOP00000007515	nploc4	ENSHCOP00000007515	ENSHCOP00000015140	Uncharacterized protein.	NPL4 homolog, ubiquitin recognition factor.	0.554
ENSHCOP00000007515	pclaf	ENSHCOP00000007515	ENSHCOP00000007478	Uncharacterized protein.	PCNA clamp associated factor.	0.598
ENSHCOP00000007515	pcna	ENSHCOP00000007515	ENSHCOP00000003160	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.992
ENSHCOP00000007515	pold1	ENSHCOP00000007515	ENSHCOP00000024706	Uncharacterized protein.	DNA polymerase.	0.883