56 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSHCOP00000006772	Uncharacterized protein. (615 aa)
	LOC109520496	Transducin (beta)-like 1 X-linked receptor 1b. (516 aa)
	grhl1	Grainyhead-like transcription factor 1. (615 aa)
	LOC109528702	Uncharacterized protein. (219 aa)
	LOC109523558	MAP7 domain containing 1a. (722 aa)
	ncoa6	Nuclear receptor coactivator 6. (2298 aa)
	ncor1	Nuclear receptor corepressor 1. (2383 aa)
	LOC109508570	Uncharacterized protein. (195 aa)
	LOC109532549	CREB binding protein b. (1735 aa)
	sin3b	SIN3 transcription regulator family member B. (1284 aa)
	Ncoa2	Uncharacterized protein. (370 aa)
	LOC109518573	Uncharacterized protein. (471 aa)
	Sin3a	SIN3 transcription regulator family member Aa. (1106 aa)
	med29	Mediator complex subunit 29. (174 aa)
	LOC109514495	Uncharacterized protein. (133 aa)
	med9	Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (99 aa)
	fabp1	Fatty acid binding protein 1b, tandem duplicate 1. (126 aa)
	med11	Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (118 aa)
	LOC109511945	MAP7 domain containing 3. (707 aa)
	LOC109527342	CREB binding protein a. (2447 aa)
	LOC109517456	Four and a half LIM domains 5. (390 aa)
	ankrd1	Ankyrin repeat domain 1a (cardiac muscle). (320 aa)
	MED26	Mediator complex subunit 26. (598 aa)
	LOC109525885	SIN3 transcription regulator family member Ab. (1287 aa)
	Med1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1528 aa)
	med18	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (209 aa)
	ppargc1a	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (915 aa)
	fam120b	Family with sequence similarity 120B. (724 aa)
	LOC109514565	Grainyhead-like transcription factor 2b. (598 aa)
	med21	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (145 aa)
	nfyb	Nuclear transcription factor Y, beta a. (203 aa)
	med19	Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (253 aa)
	LOC109532526	Uncharacterized protein. (1579 aa)
	ENSHCOP00000006319	Nuclear receptor coactivator 2. (1028 aa)
	tnfrsf21	Tumor necrosis factor receptor superfamily, member 21. (665 aa)
	carm1	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (569 aa)
	map7	Si:ch73-217b7.1. (762 aa)
	mtf1	Metal-regulatory transcription factor 1. (710 aa)
	LOC109524267	Peroxisome proliferator-activated receptor gamma, coactivator 1 beta. (748 aa)
	HDAC3	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
	nfya	Nuclear transcription factor Y, alpha, like. (348 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha b. (430 aa)
	LOC109531218	Transducin beta like 1 X-linked. (513 aa)
	thrap3	Thyroid hormone receptor associated protein 3b. (862 aa)
	ENSHCOP00000002848	Si:ch73-281i18.7. (151 aa)
	fhl2	Four and a half LIM domains 2b. (279 aa)
	LOC109518905	Uncharacterized protein. (1412 aa)
	med22	Mediator complex subunit 22. (202 aa)
	LOC109523556	Four and a half LIM domains 3a. (299 aa)
	LOC109520800	Four and a half LIM domains 3a. (279 aa)
	nfyc	Nuclear transcription factor Y, gamma. (353 aa)
	LOC109530282	Retinoid X receptor, alpha a. (444 aa)
	ncoa1	Nuclear receptor coactivator 1. (1506 aa)
	ncor2	Nuclear receptor corepressor 2. (2225 aa)
	tgs1	LYN proto-oncogene, Src family tyrosine kinase. (777 aa)
	nrf1	Nuclear respiratory factor 1. (502 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000006319	ENSHCOP00000006772	ENSHCOP00000006319	ENSHCOP00000006772	Nuclear receptor coactivator 2.	Uncharacterized protein.	0.611
ENSHCOP00000006319	LOC109527342	ENSHCOP00000006319	ENSHCOP00000017333	Nuclear receptor coactivator 2.	CREB binding protein a.	0.611
ENSHCOP00000006319	LOC109530282	ENSHCOP00000006319	ENSHCOP00000010626	Nuclear receptor coactivator 2.	Retinoid X receptor, alpha a.	0.682
ENSHCOP00000006319	LOC109532526	ENSHCOP00000006319	ENSHCOP00000006363	Nuclear receptor coactivator 2.	Uncharacterized protein.	0.611
ENSHCOP00000006319	LOC109532549	ENSHCOP00000006319	ENSHCOP00000021630	Nuclear receptor coactivator 2.	CREB binding protein b.	0.611
ENSHCOP00000006319	PPARA	ENSHCOP00000006319	ENSHCOP00000003218	Nuclear receptor coactivator 2.	Peroxisome proliferator-activated receptor alpha b.	0.614
ENSHCOP00000006319	carm1	ENSHCOP00000006319	ENSHCOP00000005975	Nuclear receptor coactivator 2.	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.670
ENSHCOP00000006319	ncoa1	ENSHCOP00000006319	ENSHCOP00000010836	Nuclear receptor coactivator 2.	Nuclear receptor coactivator 1.	0.426
ENSHCOP00000006319	ncoa6	ENSHCOP00000006319	ENSHCOP00000023387	Nuclear receptor coactivator 2.	Nuclear receptor coactivator 6.	0.462
ENSHCOP00000006319	ncor1	ENSHCOP00000006319	ENSHCOP00000022282	Nuclear receptor coactivator 2.	Nuclear receptor corepressor 1.	0.467
ENSHCOP00000006319	ncor2	ENSHCOP00000006319	ENSHCOP00000010931	Nuclear receptor coactivator 2.	Nuclear receptor corepressor 2.	0.467
ENSHCOP00000006772	ENSHCOP00000006319	ENSHCOP00000006772	ENSHCOP00000006319	Uncharacterized protein.	Nuclear receptor coactivator 2.	0.611
ENSHCOP00000006772	HDAC3	ENSHCOP00000006772	ENSHCOP00000003302	Uncharacterized protein.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.647
ENSHCOP00000006772	LOC109518905	ENSHCOP00000006772	ENSHCOP00000008835	Uncharacterized protein.	Uncharacterized protein.	0.638
ENSHCOP00000006772	LOC109525885	ENSHCOP00000006772	ENSHCOP00000014995	Uncharacterized protein.	SIN3 transcription regulator family member Ab.	0.444
ENSHCOP00000006772	LOC109530282	ENSHCOP00000006772	ENSHCOP00000010626	Uncharacterized protein.	Retinoid X receptor, alpha a.	0.521
ENSHCOP00000006772	LOC109532549	ENSHCOP00000006772	ENSHCOP00000021630	Uncharacterized protein.	CREB binding protein b.	0.925
ENSHCOP00000006772	Ncoa2	ENSHCOP00000006772	ENSHCOP00000021329	Uncharacterized protein.	Uncharacterized protein.	0.611
ENSHCOP00000006772	PPARA	ENSHCOP00000006772	ENSHCOP00000003218	Uncharacterized protein.	Peroxisome proliferator-activated receptor alpha b.	0.682
ENSHCOP00000006772	Sin3a	ENSHCOP00000006772	ENSHCOP00000020871	Uncharacterized protein.	SIN3 transcription regulator family member Aa.	0.444