22 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ubb	Ubiquitin B. (281 aa)
	LOC109518923	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (590 aa)
	rspo1	R-spondin 1. (277 aa)
	usp8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1072 aa)
	LGR6	Leucine rich repeat containing G protein-coupled receptor 6. (958 aa)
	lrp4	Low density lipoprotein receptor-related protein 4. (1845 aa)
	lrp6	Low density lipoprotein receptor-related protein 6. (1518 aa)
	lgr4	Leucine-rich repeat containing G protein-coupled receptor 4. (980 aa)
	ubc	Uncharacterized protein. (989 aa)
	rspo3	R-spondin 3. (325 aa)
	fzd6	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (678 aa)
	znrf3	Zinc and ring finger 3. (743 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (531 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC109521193	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (336 aa)
	fzd8	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	lrtm1	Leucine rich repeats and transmembrane domains 1. (368 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	LOC109510257	Uncharacterized protein. (235 aa)
	rnf43	RING-type domain-containing protein. (756 aa)
	Rspo2	R-spondin 2. (240 aa)
	ENSHCOP00000007719	Ubiquitin-like domain-containing protein. (106 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000007719	rnf43	ENSHCOP00000007719	ENSHCOP00000022762	Ubiquitin-like domain-containing protein.	RING-type domain-containing protein.	0.642
ENSHCOP00000007719	rps27a	ENSHCOP00000007719	ENSHCOP00000016034	Ubiquitin-like domain-containing protein.	Ribosomal protein S27a.	0.994
ENSHCOP00000007719	ubb	ENSHCOP00000007719	ENSHCOP00000007731	Ubiquitin-like domain-containing protein.	Ubiquitin B.	0.940
ENSHCOP00000007719	ubc	ENSHCOP00000007719	ENSHCOP00000009639	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.940
ENSHCOP00000007719	usp8	ENSHCOP00000007719	ENSHCOP00000000591	Ubiquitin-like domain-containing protein.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.851
ENSHCOP00000007719	znrf3	ENSHCOP00000007719	ENSHCOP00000011897	Ubiquitin-like domain-containing protein.	Zinc and ring finger 3.	0.643
LGR6	LOC109510257	ENSHCOP00000001485	ENSHCOP00000023502	Leucine rich repeat containing G protein-coupled receptor 6.	Uncharacterized protein.	0.659
LGR6	Rspo2	ENSHCOP00000001485	ENSHCOP00000022719	Leucine rich repeat containing G protein-coupled receptor 6.	R-spondin 2.	0.932
LGR6	lgr4	ENSHCOP00000001485	ENSHCOP00000006311	Leucine rich repeat containing G protein-coupled receptor 6.	Leucine-rich repeat containing G protein-coupled receptor 4.	0.928
LGR6	rnf43	ENSHCOP00000001485	ENSHCOP00000022762	Leucine rich repeat containing G protein-coupled receptor 6.	RING-type domain-containing protein.	0.518
LGR6	rspo3	ENSHCOP00000001485	ENSHCOP00000010941	Leucine rich repeat containing G protein-coupled receptor 6.	R-spondin 3.	0.932
LGR6	znrf3	ENSHCOP00000001485	ENSHCOP00000011897	Leucine rich repeat containing G protein-coupled receptor 6.	Zinc and ring finger 3.	0.567
LOC109510257	LGR6	ENSHCOP00000023502	ENSHCOP00000001485	Uncharacterized protein.	Leucine rich repeat containing G protein-coupled receptor 6.	0.659
LOC109510257	lgr4	ENSHCOP00000023502	ENSHCOP00000006311	Uncharacterized protein.	Leucine-rich repeat containing G protein-coupled receptor 4.	0.818
LOC109510257	rnf43	ENSHCOP00000023502	ENSHCOP00000022762	Uncharacterized protein.	RING-type domain-containing protein.	0.739
LOC109510257	rps27a	ENSHCOP00000023502	ENSHCOP00000016034	Uncharacterized protein.	Ribosomal protein S27a.	0.551
LOC109510257	rspo3	ENSHCOP00000023502	ENSHCOP00000010941	Uncharacterized protein.	R-spondin 3.	0.551
LOC109510257	ubb	ENSHCOP00000023502	ENSHCOP00000007731	Uncharacterized protein.	Ubiquitin B.	0.472
LOC109510257	ubc	ENSHCOP00000023502	ENSHCOP00000009639	Uncharacterized protein.	Uncharacterized protein.	0.472
LOC109510257	znrf3	ENSHCOP00000023502	ENSHCOP00000011897	Uncharacterized protein.	Zinc and ring finger 3.	0.741