33 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rfc4	Replication factor C (activator 1) 4. (331 aa)
	Polk	Polymerase (DNA directed) kappa. (396 aa)
	kxd1	KxDL motif containing 1. (185 aa)
	rfc2	Replication factor C (activator 1) 2. (244 aa)
	rfc1	Replication factor C subunit 1. (1130 aa)
	LOC109520855	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (527 aa)
	rfc3	Replication factor C (activator 1) 3. (356 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (611 aa)
	rpa3	Replication protein A3. (127 aa)
	pold2	Polymerase (DNA directed), delta 2, regulatory subunit. (470 aa)
	ENSHCOP00000026411	Uncharacterized protein. (408 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	pold4	Si:dkey-28b4.7. (106 aa)
	meiob	Methionine sulfoxide reductase B1b. (439 aa)
	pold1	DNA polymerase. (1105 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	pole3	Polymerase (DNA directed), epsilon 3 (p17 subunit). (148 aa)
	LOC109527038	ATPase family AAA domain containing 5a. (1619 aa)
	rpa2	Replication protein A2. (314 aa)
	ENSHCOP00000007515	Uncharacterized protein. (89 aa)
	ENSHCOP00000007719	Ubiquitin-like domain-containing protein. (106 aa)
	ubb	Ubiquitin B. (281 aa)
	LOC109526212	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (532 aa)
	pold3	Polymerase (DNA-directed), delta 3, accessory subunit. (437 aa)
	ubc	Uncharacterized protein. (989 aa)
	ENSHCOP00000028059	Uncharacterized protein. (127 aa)
	pole	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2282 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	Pole4	CBFD_NFYB_HMF domain-containing protein. (128 aa)
	rfc5	Replication factor C (activator 1) 5. (335 aa)
	LOC109517068	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (572 aa)
	pole2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (521 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000007515	ENSHCOP00000026411	ENSHCOP00000007515	ENSHCOP00000026411	Uncharacterized protein.	Uncharacterized protein.	0.926
ENSHCOP00000007515	ENSHCOP00000028059	ENSHCOP00000007515	ENSHCOP00000028059	Uncharacterized protein.	Uncharacterized protein.	0.728
ENSHCOP00000007515	LOC109517068	ENSHCOP00000007515	ENSHCOP00000009787	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.742
ENSHCOP00000007515	LOC109527038	ENSHCOP00000007515	ENSHCOP00000004580	Uncharacterized protein.	ATPase family AAA domain containing 5a.	0.926
ENSHCOP00000007515	Pole4	ENSHCOP00000007515	ENSHCOP00000018062	Uncharacterized protein.	CBFD_NFYB_HMF domain-containing protein.	0.666
ENSHCOP00000007515	Polk	ENSHCOP00000007515	ENSHCOP00000011993	Uncharacterized protein.	Polymerase (DNA directed) kappa.	0.675
ENSHCOP00000007515	meiob	ENSHCOP00000007515	ENSHCOP00000001422	Uncharacterized protein.	Methionine sulfoxide reductase B1b.	0.702
ENSHCOP00000007515	pcna	ENSHCOP00000007515	ENSHCOP00000003160	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.992
ENSHCOP00000007515	pold1	ENSHCOP00000007515	ENSHCOP00000024706	Uncharacterized protein.	DNA polymerase.	0.883
ENSHCOP00000007515	pold2	ENSHCOP00000007515	ENSHCOP00000025934	Uncharacterized protein.	Polymerase (DNA directed), delta 2, regulatory subunit.	0.858
ENSHCOP00000007515	pold3	ENSHCOP00000007515	ENSHCOP00000009331	Uncharacterized protein.	Polymerase (DNA-directed), delta 3, accessory subunit.	0.598
ENSHCOP00000007515	pole	ENSHCOP00000007515	ENSHCOP00000021284	Uncharacterized protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.849
ENSHCOP00000007515	pole2	ENSHCOP00000007515	ENSHCOP00000010649	Uncharacterized protein.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.896
ENSHCOP00000007515	pole3	ENSHCOP00000007515	ENSHCOP00000004499	Uncharacterized protein.	Polymerase (DNA directed), epsilon 3 (p17 subunit).	0.726
ENSHCOP00000007515	rfc1	ENSHCOP00000007515	ENSHCOP00000001479	Uncharacterized protein.	Replication factor C subunit 1.	0.977
ENSHCOP00000007515	rfc2	ENSHCOP00000007515	ENSHCOP00000023251	Uncharacterized protein.	Replication factor C (activator 1) 2.	0.984
ENSHCOP00000007515	rfc3	ENSHCOP00000007515	ENSHCOP00000021883	Uncharacterized protein.	Replication factor C (activator 1) 3.	0.995
ENSHCOP00000007515	rfc5	ENSHCOP00000007515	ENSHCOP00000017308	Uncharacterized protein.	Replication factor C (activator 1) 5.	0.992
ENSHCOP00000007515	rpa1	ENSHCOP00000007515	ENSHCOP00000000570	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.742
ENSHCOP00000007515	rpa2	ENSHCOP00000007515	ENSHCOP00000005090	Uncharacterized protein.	Replication protein A2.	0.725