37 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PIP4K2B	Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (411 aa)
	LOC109522364	Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma b. (401 aa)
	ENSHCOP00000026987	Helicase ATP-binding domain-containing protein. (452 aa)
	chd4	Uncharacterized protein. (1636 aa)
	LOC109506970	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
	LOC109523146	Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a. (419 aa)
	rbbp4	Retinoblastoma binding protein 4. (424 aa)
	LOC109521578	Uncharacterized protein. (1590 aa)
	LOC109514850	E1A binding protein p300 b. (2669 aa)
	pip4p1	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (271 aa)
	brd1	Bromodomain containing 1a. (1254 aa)
	LOC109528457	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (376 aa)
	chd3	Chromodomain helicase DNA binding protein 3. (2012 aa)
	gatad2b	GATA zinc finger domain containing 2B. (549 aa)
	LOC109532150	GATA zinc finger domain containing 2Ab. (620 aa)
	brd7	Bromodomain containing 7. (602 aa)
	LOC109529213	Bromodomain and PHD finger containing, 3a. (1200 aa)
	pip4p2	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
	ENSHCOP00000014971	CHDCT2 domain-containing protein. (246 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (395 aa)
	ENSHCOP00000014803	EPL1 domain-containing protein. (273 aa)
	ing5	Inhibitor of growth family, member 5a. (229 aa)
	brd9	Bromodomain containing 9. (653 aa)
	ENSHCOP00000011447	CHDCT2 domain-containing protein. (232 aa)
	ing1	Inhibitor of growth protein. (308 aa)
	LOC109526229	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (483 aa)
	ing2	Inhibitor of growth protein. (290 aa)
	pip4k2a	Phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a. (405 aa)
	LOC109522937	Uncharacterized protein. (778 aa)
	LOC109512841	E1A binding protein p300 a. (2561 aa)
	ENSHCOP00000007796	V-akt murine thymoma viral oncogene homolog 3b; Belongs to the protein kinase superfamily. (393 aa)
	brpf1	Uncharacterized protein. (1299 aa)
	kat6a	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2280 aa)
	meaf6	MYST/Esa1-associated factor 6. (195 aa)
	LOC109507328	Uncharacterized protein. (719 aa)
	LOC109510167	Non-specific serine/threonine protein kinase. (480 aa)
	LOC109517783	Bromodomain and PHD finger containing, 3b. (1155 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000007796	meaf6	ENSHCOP00000007796	ENSHCOP00000002833	V-akt murine thymoma viral oncogene homolog 3b; Belongs to the protein kinase superfamily.	MYST/Esa1-associated factor 6.	0.451
ENSHCOP00000011447	ENSHCOP00000026987	ENSHCOP00000011447	ENSHCOP00000026987	CHDCT2 domain-containing protein.	Helicase ATP-binding domain-containing protein.	0.552
ENSHCOP00000011447	LOC109507328	ENSHCOP00000011447	ENSHCOP00000000362	CHDCT2 domain-containing protein.	Uncharacterized protein.	0.681
ENSHCOP00000011447	LOC109532150	ENSHCOP00000011447	ENSHCOP00000017674	CHDCT2 domain-containing protein.	GATA zinc finger domain containing 2Ab.	0.681
ENSHCOP00000011447	gatad2b	ENSHCOP00000011447	ENSHCOP00000019541	CHDCT2 domain-containing protein.	GATA zinc finger domain containing 2B.	0.681
ENSHCOP00000011447	meaf6	ENSHCOP00000011447	ENSHCOP00000002833	CHDCT2 domain-containing protein.	MYST/Esa1-associated factor 6.	0.553
ENSHCOP00000011447	rbbp4	ENSHCOP00000011447	ENSHCOP00000024844	CHDCT2 domain-containing protein.	Retinoblastoma binding protein 4.	0.836
ENSHCOP00000014803	LOC109517783	ENSHCOP00000014803	ENSHCOP00000002741	EPL1 domain-containing protein.	Bromodomain and PHD finger containing, 3b.	0.489
ENSHCOP00000014803	LOC109522937	ENSHCOP00000014803	ENSHCOP00000008040	EPL1 domain-containing protein.	Uncharacterized protein.	0.897
ENSHCOP00000014803	LOC109528457	ENSHCOP00000014803	ENSHCOP00000022970	EPL1 domain-containing protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.448
ENSHCOP00000014803	LOC109529213	ENSHCOP00000014803	ENSHCOP00000016937	EPL1 domain-containing protein.	Bromodomain and PHD finger containing, 3a.	0.487
ENSHCOP00000014803	brd7	ENSHCOP00000014803	ENSHCOP00000017306	EPL1 domain-containing protein.	Bromodomain containing 7.	0.439
ENSHCOP00000014803	brd9	ENSHCOP00000014803	ENSHCOP00000012450	EPL1 domain-containing protein.	Bromodomain containing 9.	0.490
ENSHCOP00000014803	ing1	ENSHCOP00000014803	ENSHCOP00000010831	EPL1 domain-containing protein.	Inhibitor of growth protein.	0.501
ENSHCOP00000014803	ing2	ENSHCOP00000014803	ENSHCOP00000009147	EPL1 domain-containing protein.	Inhibitor of growth protein.	0.531
ENSHCOP00000014803	ing5	ENSHCOP00000014803	ENSHCOP00000013489	EPL1 domain-containing protein.	Inhibitor of growth family, member 5a.	0.639
ENSHCOP00000014803	kat6a	ENSHCOP00000014803	ENSHCOP00000002943	EPL1 domain-containing protein.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.592
ENSHCOP00000014803	meaf6	ENSHCOP00000014803	ENSHCOP00000002833	EPL1 domain-containing protein.	MYST/Esa1-associated factor 6.	0.838
ENSHCOP00000014971	ENSHCOP00000026987	ENSHCOP00000014971	ENSHCOP00000026987	CHDCT2 domain-containing protein.	Helicase ATP-binding domain-containing protein.	0.530
ENSHCOP00000014971	LOC109507328	ENSHCOP00000014971	ENSHCOP00000000362	CHDCT2 domain-containing protein.	Uncharacterized protein.	0.682