22 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109531377	Zinc finger protein 385A. (436 aa)
	pou4f1	POU domain protein. (335 aa)
	LOC109510167	Non-specific serine/threonine protein kinase. (480 aa)
	phf20	PHD finger protein 20, a. (985 aa)
	ENSHCOP00000002541	POU domain protein. (341 aa)
	znf385c	Zinc finger protein 385C. (507 aa)
	LOC109516740	POU domain protein. (332 aa)
	ENSHCOP00000007796	V-akt murine thymoma viral oncogene homolog 3b; Belongs to the protein kinase superfamily. (393 aa)
	LOC109526229	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (483 aa)
	tp63	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (544 aa)
	tp73	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (571 aa)
	ppp1r13l	Protein phosphatase 1, regulatory subunit 13 like. (780 aa)
	ENSHCOP00000023215	Uncharacterized protein. (106 aa)
	LOC109528457	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (376 aa)
	banp	BTG3 associated nuclear protein. (521 aa)
	ppp1r13b	Protein phosphatase 1, regulatory subunit 13Bb. (1057 aa)
	pou4f2	POU domain protein. (405 aa)
	ENSHCOP00000018976	C2H2-type domain-containing protein. (357 aa)
	tp53bp2	Tumor protein p53 binding protein, 2a. (928 aa)
	ZNF385A	Zinc finger protein 385A. (358 aa)
	LOC109523970	C2H2-type domain-containing protein. (536 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (395 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000002541	LOC109528457	ENSHCOP00000002541	ENSHCOP00000022970	POU domain protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.478
ENSHCOP00000007796	ENSHCOP00000023215	ENSHCOP00000007796	ENSHCOP00000023215	V-akt murine thymoma viral oncogene homolog 3b; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.443
ENSHCOP00000007796	phf20	ENSHCOP00000007796	ENSHCOP00000002142	V-akt murine thymoma viral oncogene homolog 3b; Belongs to the protein kinase superfamily.	PHD finger protein 20, a.	0.443
ENSHCOP00000018976	LOC109528457	ENSHCOP00000018976	ENSHCOP00000022970	C2H2-type domain-containing protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.488
ENSHCOP00000023215	ENSHCOP00000007796	ENSHCOP00000023215	ENSHCOP00000007796	Uncharacterized protein.	V-akt murine thymoma viral oncogene homolog 3b; Belongs to the protein kinase superfamily.	0.443
ENSHCOP00000023215	LOC109510167	ENSHCOP00000023215	ENSHCOP00000001382	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.473
ENSHCOP00000023215	LOC109526229	ENSHCOP00000023215	ENSHCOP00000010271	Uncharacterized protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.473
ENSHCOP00000023215	LOC109528457	ENSHCOP00000023215	ENSHCOP00000022970	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.730
ENSHCOP00000023215	akt1	ENSHCOP00000023215	ENSHCOP00000014845	Uncharacterized protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.473
ENSHCOP00000023215	tp63	ENSHCOP00000023215	ENSHCOP00000011142	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.408
ENSHCOP00000023215	tp73	ENSHCOP00000023215	ENSHCOP00000028288	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.408
LOC109510167	ENSHCOP00000023215	ENSHCOP00000001382	ENSHCOP00000023215	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.473
LOC109510167	LOC109526229	ENSHCOP00000001382	ENSHCOP00000010271	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.940
LOC109510167	akt1	ENSHCOP00000001382	ENSHCOP00000014845	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
LOC109510167	phf20	ENSHCOP00000001382	ENSHCOP00000002142	Non-specific serine/threonine protein kinase.	PHD finger protein 20, a.	0.473
LOC109516740	LOC109528457	ENSHCOP00000007541	ENSHCOP00000022970	POU domain protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.478
LOC109523970	LOC109528457	ENSHCOP00000016499	ENSHCOP00000022970	C2H2-type domain-containing protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.488
LOC109526229	ENSHCOP00000023215	ENSHCOP00000010271	ENSHCOP00000023215	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.473
LOC109526229	LOC109510167	ENSHCOP00000010271	ENSHCOP00000001382	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.940
LOC109526229	akt1	ENSHCOP00000010271	ENSHCOP00000014845	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901