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pip4k2a pip4k2a LOC109522364 LOC109522364 LOC109506970 LOC109506970 LOC109523146 LOC109523146 LOC109512841 LOC109512841 LOC109514850 LOC109514850 pip4p1 pip4p1 LOC109528457 LOC109528457 pip4p2 pip4p2 ing1 ing1 ing2 ing2 PIP4K2B PIP4K2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pip4k2aPhosphatidylinositol-5-phosphate 4-kinase, type II, alpha a. (405 aa)
LOC109522364Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma b. (401 aa)
LOC109506970Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
LOC109523146Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a. (419 aa)
LOC109512841E1A binding protein p300 a. (2561 aa)
LOC109514850E1A binding protein p300 b. (2669 aa)
pip4p1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (271 aa)
LOC109528457Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (376 aa)
pip4p2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
ing1Inhibitor of growth protein. (308 aa)
ing2Inhibitor of growth protein. (290 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (411 aa)
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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