65 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sp1	Sp1 transcription factor. (523 aa)
	src	Tyrosine-protein kinase. (543 aa)
	usp8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1072 aa)
	rras2	RAS related 2. (202 aa)
	LOC109527013	Zgc:55558. (187 aa)
	LOC109521335	BZIP domain-containing protein; Belongs to the bZIP family. (312 aa)
	tax1bp1	Tax1 (human T-cell leukemia virus type I) binding protein 1b. (830 aa)
	gabarapl2	GABA type A receptor associated protein like 2. (117 aa)
	bcl2l13	BCL2 like 13. (519 aa)
	LOC109520247	Activating transcription factor 4b. (436 aa)
	nbr1	NBR1 autophagy cargo receptor b. (921 aa)
	LOC109513573	Tyrosine-protein kinase. (538 aa)
	gabarap	GABA(A) receptor-associated protein b. (122 aa)
	usp30	Ubiquitin carboxyl-terminal hydrolase. (498 aa)
	ulk1	Unc-51 like autophagy activating kinase 1. (940 aa)
	LOC109513124	Mitogen-activated protein kinase. (384 aa)
	hras	HRas proto-oncogene, GTPase a. (190 aa)
	LOC109508419	V-rel avian reticuloendotheliosis viral oncogene homolog A. (627 aa)
	fis1	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (154 aa)
	LOC109524764	RAS related. (197 aa)
	mapk10	Mitogen-activated protein kinase. (384 aa)
	optn	Optineurin. (530 aa)
	FUNDC1	FUN14 domain containing 1. (157 aa)
	LOC109512410	NBR1 autophagy cargo receptor a. (1035 aa)
	ubc	Uncharacterized protein. (989 aa)
	hif1a	Hypoxia inducible factor 1 subunit alpha a. (745 aa)
	LOC109517597	Zgc:86598; Belongs to the protein kinase superfamily. (392 aa)
	eif2ak3	Eukaryotic translation initiation factor 2-alpha kinase 3. (1106 aa)
	LOC109529364	Hypoxia inducible factor 1 subunit alpha, like. (661 aa)
	csnk2a2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (349 aa)
	LOC109510179	BCL2 interacting protein 3. (191 aa)
	LOC109518742	Mitogen-activated protein kinase. (420 aa)
	LOC109519981	Uncharacterized protein. (208 aa)
	mras	Muscle RAS oncogene homolog. (208 aa)
	mfn1	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (758 aa)
	LOC109508177	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC109512691	Mitogen-activated protein kinase. (411 aa)
	LOC109525077	BCL2 interacting protein 3 like a. (234 aa)
	pgam5	PGAM family member 5, serine/threonine protein phosphatase, mitochondrial. (306 aa)
	RAB7A	RAB7A, member RAS oncogene family. (207 aa)
	e2f1	E2F transcription factor 1. (428 aa)
	LOC109527036	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (609 aa)
	LOC109514370	Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily. (348 aa)
	csnk2b	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
	bcl2l1	BCL2 like 1. (225 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	tbc1d17	TBC1 domain family, member 17. (623 aa)
	tbc1d15	TBC1 domain family, member 15. (673 aa)
	Tfe3	Transcription factor binding to IGHM enhancer 3b. (457 aa)
	atf4	Activating transcription factor 4a. (345 aa)
	TOMM7	Translocase of outer mitochondrial membrane 7. (51 aa)
	KRAS	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	LOC109528457	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (376 aa)
	MITF	Melanocyte inducing transcription factor b. (512 aa)
	mfn2	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (758 aa)
	rhot2	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (618 aa)
	LOC109522217	RAB7a, member RAS oncogene family. (207 aa)
	LOC109512001	Tax1 (human T-cell leukemia virus type I) binding protein 1a. (940 aa)
	LOC109517316	Fork-head domain-containing protein. (572 aa)
	LOC109511185	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (581 aa)
	LOC109527968	Zgc:73226. (182 aa)
	LOC109521190	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (806 aa)
	atg9a	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (853 aa)
	becn1	Beclin 1, autophagy related. (447 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FUNDC1	LOC109508177	ENSHCOP00000009120	ENSHCOP00000015816	FUN14 domain containing 1.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.945
FUNDC1	LOC109510179	ENSHCOP00000009120	ENSHCOP00000012766	FUN14 domain containing 1.	BCL2 interacting protein 3.	0.566
FUNDC1	LOC109512410	ENSHCOP00000009120	ENSHCOP00000009432	FUN14 domain containing 1.	NBR1 autophagy cargo receptor a.	0.573
FUNDC1	LOC109513573	ENSHCOP00000009120	ENSHCOP00000006859	FUN14 domain containing 1.	Tyrosine-protein kinase.	0.938
FUNDC1	LOC109514370	ENSHCOP00000009120	ENSHCOP00000020295	FUN14 domain containing 1.	Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily.	0.945
FUNDC1	LOC109517597	ENSHCOP00000009120	ENSHCOP00000010142	FUN14 domain containing 1.	Zgc:86598; Belongs to the protein kinase superfamily.	0.945
FUNDC1	LOC109519981	ENSHCOP00000009120	ENSHCOP00000014179	FUN14 domain containing 1.	Uncharacterized protein.	0.901
FUNDC1	bcl2l13	ENSHCOP00000009120	ENSHCOP00000004987	FUN14 domain containing 1.	BCL2 like 13.	0.536
FUNDC1	csnk2a2	ENSHCOP00000009120	ENSHCOP00000012626	FUN14 domain containing 1.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.945
FUNDC1	csnk2b	ENSHCOP00000009120	ENSHCOP00000020898	FUN14 domain containing 1.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.959
FUNDC1	gabarap	ENSHCOP00000009120	ENSHCOP00000007013	FUN14 domain containing 1.	GABA(A) receptor-associated protein b.	0.966
FUNDC1	gabarapl2	ENSHCOP00000009120	ENSHCOP00000004541	FUN14 domain containing 1.	GABA type A receptor associated protein like 2.	0.966
FUNDC1	nbr1	ENSHCOP00000009120	ENSHCOP00000006684	FUN14 domain containing 1.	NBR1 autophagy cargo receptor b.	0.573
FUNDC1	pgam5	ENSHCOP00000009120	ENSHCOP00000018563	FUN14 domain containing 1.	PGAM family member 5, serine/threonine protein phosphatase, mitochondrial.	0.977
FUNDC1	src	ENSHCOP00000009120	ENSHCOP00000000379	FUN14 domain containing 1.	Tyrosine-protein kinase.	0.938
FUNDC1	ulk1	ENSHCOP00000009120	ENSHCOP00000007413	FUN14 domain containing 1.	Unc-51 like autophagy activating kinase 1.	0.962
KRAS	LOC109513573	ENSHCOP00000022952	ENSHCOP00000006859	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	Tyrosine-protein kinase.	0.517
KRAS	LOC109527013	ENSHCOP00000022952	ENSHCOP00000003443	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	Zgc:55558.	0.901
KRAS	bcl2l1	ENSHCOP00000022952	ENSHCOP00000021075	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	BCL2 like 1.	0.597
KRAS	hras	ENSHCOP00000022952	ENSHCOP00000007484	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	HRas proto-oncogene, GTPase a.	0.909