STRINGSTRING
LOC109521916 LOC109521916 LOC109507318 LOC109507318 LOC109510605 LOC109510605 nprl2 nprl2 igf1r igf1r LOC109527142 LOC109527142 LOC109521689 LOC109521689 LOC109528682 LOC109528682 LOC109528419 LOC109528419 LOC109510167 LOC109510167 skp2 skp2 LOC109510414 LOC109510414 Wnt8b Wnt8b rps6ka6 rps6ka6 strada strada mtor mtor LOC109522461 LOC109522461 fzd3 fzd3 telo2 telo2 LOC109524381 LOC109524381 LOC109527906 LOC109527906 LOC109529904 LOC109529904 PIK3R3 PIK3R3 LOC109527013 LOC109527013 LOC109512406 LOC109512406 atp6v1d atp6v1d gsk3b gsk3b prkaa1 prkaa1 lpin2 lpin2 mios mios LOC109522387 LOC109522387 lrp6 lrp6 LOC109511764 LOC109511764 LOC109512526 LOC109512526 LOC109526434 LOC109526434 lamtor4 lamtor4 lamtor2 lamtor2 LOC109524215 LOC109524215 LOC109520209 LOC109520209 WNT2B WNT2B SGK1 SGK1 LOC109518522 LOC109518522 Fzd2 Fzd2 akt1s1 akt1s1 LOC109523151 LOC109523151 LOC109520879 LOC109520879 ulk1 ulk1 hras hras LOC109516720 LOC109516720 eif4b eif4b LOC109511654 LOC109511654 LOC109518923 LOC109518923 lpin1 lpin1 LOC109528785 LOC109528785 LOC109526748 LOC109526748 rps6kb1 rps6kb1 deptor deptor slc7a5 slc7a5 LOC109508359 LOC109508359 LOC109531171 LOC109531171 LOC109531620 LOC109531620 LOC109526229 LOC109526229 EIF4E EIF4E fzd9 fzd9 LOC109513456 LOC109513456 atp6v1c1 atp6v1c1 Fzd10 Fzd10 fzd6 fzd6 PRR5 PRR5 LOC109514865 LOC109514865 lamtor3 lamtor3 LOC109520091 LOC109520091 fzd4 fzd4 wdr24 wdr24 LOC109530170 LOC109530170 ddit4 ddit4 pik3cb pik3cb LOC109517881 LOC109517881 wnt9b wnt9b LOC109515323 LOC109515323 slc3a2 slc3a2 LOC109528579 LOC109528579 akt1 akt1 rps6 rps6 wnt9a wnt9a FZD7 FZD7 atp6v1h atp6v1h LOC109519094 LOC109519094 prkca prkca LOC109531368 LOC109531368 Clip1 Clip1 LOC109526599 LOC109526599 LOC109521193 LOC109521193 fzd8 fzd8 flcn flcn LOC109511124 LOC109511124 LOC109510126 LOC109510126 LOC109520494 LOC109520494 LOC109517920 LOC109517920 seh1l seh1l LOC109525278 LOC109525278 castor1 castor1 mlst8 mlst8 LOC109507385 LOC109507385 LOC109524221 LOC109524221 LOC109524189 LOC109524189 ENSHCOP00000018371 ENSHCOP00000018371 Wnt1 Wnt1 lamtor5 lamtor5 LOC109523829 LOC109523829 LOC109509932 LOC109509932 LOC109513166 LOC109513166 tti1 tti1 ENSHCOP00000019550 ENSHCOP00000019550 LOC109508083 LOC109508083 PTEN PTEN rragc rragc atp6v1e1 atp6v1e1 wdr59 wdr59 wnt16 wnt16 LOC109521023 LOC109521023 atp6v1f atp6v1f Nprl3 Nprl3 LOC109523686 LOC109523686 LOC109528912 LOC109528912 mapk1 mapk1 LOC109519133 LOC109519133 grb2 grb2 LOC109525170 LOC109525170 KRAS KRAS dvl2 dvl2 LOC109513527 LOC109513527 LOC109507783 LOC109507783 ENSHCOP00000023911 ENSHCOP00000023911 wnt11 wnt11 sec13 sec13 LOC109516542 LOC109516542 rps6ka1 rps6ka1 wnt4 wnt4 rheb rheb lamtor1 lamtor1 slc38a9 slc38a9 mapkap1 mapkap1 LOC109531524 LOC109531524 pdpk1 pdpk1 PRKCB PRKCB rictor rictor LOC109516272 LOC109516272 cab39 cab39 prkaa2 prkaa2 LOC109515380 LOC109515380 LOC109509805 LOC109509805 LOC109515231 LOC109515231 atp6v1a atp6v1a wnt6 wnt6 LOC109509564 LOC109509564
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC109521916Growth factor receptor-bound protein 10b. (622 aa)
LOC109507318Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (271 aa)
LOC109510605Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
nprl2NPR2 like, GATOR1 complex subunit. (380 aa)
igf1rTyrosine-protein kinase receptor. (1409 aa)
LOC109527142Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (738 aa)
LOC109521689Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (470 aa)
LOC109528682Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
LOC109528419Ras homolog gene family, member Aa. (193 aa)
LOC109510167Non-specific serine/threonine protein kinase. (480 aa)
skp2S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (425 aa)
LOC109510414Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
Wnt8bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (336 aa)
rps6ka6Non-specific serine/threonine protein kinase. (715 aa)
stradaSTE20 related adaptor alpha. (418 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2512 aa)
LOC109522461Ras homolog, mTORC1 binding like 1. (184 aa)
fzd3Frizzled class receptor 3a; Belongs to the G-protein coupled receptor Fz/Smo family. (689 aa)
telo2TEL2, telomere maintenance 2, homolog (S. cerevisiae). (813 aa)
LOC109524381Calcium binding protein 39, like 1. (343 aa)
LOC109527906V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
LOC109529904Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
PIK3R3Uncharacterized protein. (468 aa)
LOC109527013Zgc:55558. (187 aa)
LOC109512406Si:ch211-284e13.4. (1119 aa)
atp6v1dATPase H+ transporting V1 subunit D. (248 aa)
gsk3bGlycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (421 aa)
prkaa1Non-specific serine/threonine protein kinase. (569 aa)
lpin2Lipin 2. (897 aa)
miosMissing oocyte, meiosis regulator, homolog (Drosophila). (878 aa)
LOC109522387Uncharacterized protein. (193 aa)
lrp6Low density lipoprotein receptor-related protein 6. (1518 aa)
LOC109511764Uncharacterized protein. (262 aa)
LOC109512526Ras-related GTP binding A. (323 aa)
LOC109526434Si:dkey-202g17.3. (496 aa)
lamtor4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (106 aa)
lamtor2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa)
LOC109524215Eukaryotic translation initiation factor 4ea; Belongs to the eukaryotic initiation factor 4E family. (253 aa)
LOC109520209Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa)
LOC109518522Ribosomal protein S6 kinase, polypeptide 3b. (674 aa)
Fzd2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa)
akt1s1AKT1 substrate 1 (proline-rich). (346 aa)
LOC109523151Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (502 aa)
LOC109520879Calcium binding protein 39-like. (334 aa)
ulk1Unc-51 like autophagy activating kinase 1. (940 aa)
hrasHRas proto-oncogene, GTPase a. (190 aa)
LOC109516720Cytosolic arginine sensor for mTORC1 subunit 2. (324 aa)
eif4bEukaryotic translation initiation factor 4Bb. (631 aa)
LOC109511654Uncharacterized protein. (118 aa)
LOC109518923Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (590 aa)
lpin1Si:ch73-21k16.1. (765 aa)
LOC109528785Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (394 aa)
LOC109526748Proline rich 5a (renal). (458 aa)
rps6kb1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (504 aa)
deptorDEP domain containing MTOR-interacting protein. (401 aa)
slc7a5Solute carrier family 7 member 5. (497 aa)
LOC109508359Si:ch73-335l21.1. (1253 aa)
LOC109531171Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (489 aa)
LOC109531620Uncharacterized protein. (683 aa)
LOC109526229Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (483 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (199 aa)
fzd9Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
LOC109513456Uncharacterized protein. (723 aa)
atp6v1c1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (383 aa)
Fzd10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (567 aa)
fzd6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (678 aa)
PRR5Proline rich 5. (406 aa)
LOC109514865Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
lamtor3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
LOC109520091Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (531 aa)
wdr24WD repeat domain 24. (843 aa)
LOC109530170Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (339 aa)
ddit4DNA-damage-inducible transcript 4. (210 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1076 aa)
LOC109517881IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (116 aa)
wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
LOC109515323Tumor necrosis factor receptor superfamily, member 1a. (383 aa)
slc3a2Aamy domain-containing protein. (511 aa)
LOC109528579Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (704 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (395 aa)
rps640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
wnt9aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (525 aa)
atp6v1hV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (484 aa)
LOC109519094V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
prkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
LOC109531368Uncharacterized protein. (193 aa)
Clip1Uncharacterized protein. (351 aa)
LOC109526599Uncharacterized protein. (560 aa)
LOC109521193Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (336 aa)
fzd8Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
flcnFolliculin. (550 aa)
LOC109511124Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (667 aa)
LOC109510126Uncharacterized protein. (213 aa)
LOC109520494Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1059 aa)
LOC109517920Uncharacterized protein. (617 aa)
seh1lSEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family. (415 aa)
LOC109525278Uncharacterized protein. (1008 aa)
castor1Uncharacterized protein. (333 aa)
mlst8MTOR associated protein, LST8 homolog (S. cerevisiae). (326 aa)
LOC109507385Tyrosine-protein kinase receptor. (1359 aa)
LOC109524221Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (332 aa)
LOC109524189Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
ENSHCOP00000018371Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (277 aa)
Wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
lamtor5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (95 aa)
LOC109523829Uncharacterized protein. (379 aa)
LOC109509932Eukaryotic translation initiation factor 4E family member 1c; Belongs to the eukaryotic initiation factor 4E family. (209 aa)
LOC109513166Tyrosine-protein kinase receptor. (1329 aa)
tti1TELO2 interacting protein 1. (1097 aa)
ENSHCOP00000019550Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (363 aa)
LOC109508083Eukaryotic translation initiation factor 4E binding protein 1. (119 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (407 aa)
rragcUncharacterized protein. (383 aa)
atp6v1e1ATPase H+ transporting V1 subunit E1a. (226 aa)
wdr59WD repeat domain 59. (942 aa)
wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (347 aa)
LOC109521023Tumor necrosis factor b (TNF superfamily, member 2); Belongs to the tumor necrosis factor family. (266 aa)
atp6v1fV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
Nprl3Uncharacterized protein. (78 aa)
LOC109523686ATPase H+ transporting V1 subunit E1b. (226 aa)
LOC109528912Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (143 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa)
LOC109519133Uncharacterized protein. (411 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC109525170Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (946 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
dvl2Dishevelled segment polarity protein 2. (693 aa)
LOC109513527Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (426 aa)
LOC109507783Protein kinase domain-containing protein. (427 aa)
ENSHCOP00000023911Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (344 aa)
wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
sec13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (320 aa)
LOC109516542Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (220 aa)
rps6ka1Ribosomal protein S6 kinase. (735 aa)
wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
rhebRas homolog, mTORC1 binding. (184 aa)
lamtor1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (159 aa)
slc38a9Solute carrier family 38 member 9. (564 aa)
mapkap1MAPK associated protein 1. (528 aa)
LOC109531524Ribosomal protein S6 kinase. (731 aa)
pdpk13-phosphoinositide dependent protein kinase 1b. (556 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa)
rictorRPTOR independent companion of MTOR, complex 2 a. (1144 aa)
LOC109516272Component of inhibitor of nuclear factor kappa B kinase complex. (739 aa)
cab39Calcium binding protein 39. (341 aa)
prkaa2Non-specific serine/threonine protein kinase. (548 aa)
LOC109515380Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
LOC109509805Sestrin 2. (548 aa)
LOC109515231Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
atp6v1aATPase H+ transporting V1 subunit A. (654 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
LOC109509564Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (162 aa)
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
Server load: low (18%) [HD]