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KQS_02530 KQS_02530 aroA aroA aroK aroK aroE aroE pabB pabB aroB aroB KQS_06940 KQS_06940 KQS_06945 KQS_06945 KQS_06950 KQS_06950 hisIE hisIE hisF hisF hisA hisA hisH hisH hisB hisB hisC hisC hisD hisD hisG hisG KQS_06995 KQS_06995 KQS_07000 KQS_07000 aroC aroC trpA trpA trpB trpB trpF trpF trpC trpC trpD trpD pabA pabA trpE trpE aroQ aroQ
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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KQS_02530Putative phospho-2-dehydro-3-deoxyheptonate aldolase. (360 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (426 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (172 aa)
aroEShikimate dehydrogenase. (252 aa)
pabBPara-aminobenzoate synthase component I. (435 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (356 aa)
KQS_06940Protein of unknown function. (222 aa)
KQS_06945Mandelate racemase / muconate lactonizing enzyme family protein. (338 aa)
KQS_06950Acyl-CoA hydrolase family protein. (131 aa)
hisIEHistidine biosynthesis bifunctional protein HisIE [Includes: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphatase]; In the N-terminal section; belongs to the PRA-CH family. (206 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa)
hisA1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase. (240 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (193 aa)
hisBHistidine biosynthesis bifunctional protein HisB [Includes: Histidinol-phosphatase (EC 3.1.3.15); Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) (IGPD)]. (379 aa)
hisCHistidinol-phosphate transaminase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (346 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (427 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (285 aa)
KQS_06995Probable transmembrane protein of unknown function. (166 aa)
KQS_07000Probable phosphoglycerol transferase. (697 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (353 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (253 aa)
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (393 aa)
trpFPhosphoribosylanthranilate isomerase; Belongs to the TrpF family. (217 aa)
trpCIndole-3-glycerol phosphate synthase. (260 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (334 aa)
pabAPara-aminobenzoate/anthranilate synthase glutamine amidotransferase component II. (187 aa)
trpEAnthranilate synthase component I. (463 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (137 aa)
Your Current Organism:
Flavobacterium indicum
NCBI taxonomy Id: 1094466
Other names: F. indicum GPTSA100-9 = DSM 17447, Flavobacterium indicum CIP 109464, Flavobacterium indicum DSM 17447, Flavobacterium indicum DSM 17447 = GPTSA100-9, Flavobacterium indicum GPTSA100-9, Flavobacterium indicum GPTSA100-9 = DSM 17447, Flavobacterium sp. GPTSA100-9
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