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KQS_01225 KQS_01225 rmlD rmlD KQS_12695 KQS_12695 KQS_12545 KQS_12545 murB murB KQS_09480 KQS_09480 gpsA gpsA serA serA icd1 icd1 mdh mdh KQS_07010 KQS_07010 hisD hisD ilvC ilvC KQS_05605 KQS_05605 aroE aroE fcl fcl icd2 icd2 guaB guaB ribD ribD wbpO wbpO ugd ugd KQS_03270 KQS_03270 KQS_02515 KQS_02515 thrA thrA metX metX maeB maeB mvaA mvaA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KQS_012253-oxoacyl-[acyl-carrier-protein] reductase. (244 aa)
rmlDdTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (309 aa)
KQS_12695Putative phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)
KQS_12545Protein of unknown function. (133 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (337 aa)
KQS_09480Probable alcohol dehydrogenase. (388 aa)
gpsAGlycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (331 aa)
serAPhosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)
icd1Isocitrate dehydrogenase (NADP+). (476 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (311 aa)
KQS_070103-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (427 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (347 aa)
KQS_056053-hydroxyacyl-CoA dehydrogenase family protein. (296 aa)
aroEShikimate dehydrogenase. (252 aa)
fclGDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (307 aa)
icd2Monomeric isocitrate dehydrogenase, NADP-dependent; Belongs to the monomeric-type IDH family. (738 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa)
ribDRiboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (346 aa)
wbpOUDP-N-acetyl-D-galactosamine dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (428 aa)
ugdUDP-glucose 6-dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (462 aa)
KQS_03270NAD-dependent epimerase/dehydratase family protein probably involved in polysaccharide biosynthesis. (328 aa)
KQS_02515Probable short-chain type dehydrogenase. (227 aa)
thrABifunctional enzyme : aspartate kinase/homoserine dehydrogenase. (802 aa)
metXHomoserine O-acetyltransferase. (325 aa)
maeBMalate dehydrogenase (oxaloacetate-decarboxylating) (NADP+). (764 aa)
mvaAProbable hydroxymethylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. (438 aa)
Your Current Organism:
Flavobacterium indicum
NCBI taxonomy Id: 1094466
Other names: F. indicum GPTSA100-9 = DSM 17447, Flavobacterium indicum CIP 109464, Flavobacterium indicum DSM 17447, Flavobacterium indicum DSM 17447 = GPTSA100-9, Flavobacterium indicum GPTSA100-9, Flavobacterium indicum GPTSA100-9 = DSM 17447, Flavobacterium sp. GPTSA100-9
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