STRINGSTRING
pyrC1 pyrC1 KQS_12250 KQS_12250 KQS_12915 KQS_12915 ansA ansA KQS_01575 KQS_01575 KQS_01640 KQS_01640 tadA tadA purH purH folE folE speB speB cdd cdd ribD ribD npdA npdA KQS_03780 KQS_03780 def def folE2 folE2 hutI hutI glsA glsA KQS_05210 KQS_05210 KQS_05215 KQS_05215 pyrG pyrG hisIE hisIE hisH hisH lpxC/fabZ lpxC/fabZ KQS_07155 KQS_07155 KQS_07160 KQS_07160 ribBA ribBA KQS_09875 KQS_09875 pyrC2 pyrC2 KQS_10115 KQS_10115 folD folD KQS_10940 KQS_10940 fjo29 fjo29 nadE nadE KQS_12125 KQS_12125
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pyrC1Dihydroorotase. (446 aa)
KQS_12250Probable arylformamidase. (253 aa)
KQS_12915Histone deacetylase family protein. (300 aa)
ansAAsparaginase 1. (335 aa)
KQS_01575Probable polysaccharide deacetylase. (207 aa)
KQS_01640Nitrilase. (326 aa)
tadAProbable cytosine/adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
purHBifunctional purine biosynthesis protein PurH. (508 aa)
folEGTP cyclohydrolase I. (228 aa)
speBAgmatinase; Belongs to the arginase family. (359 aa)
cddCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (160 aa)
ribDRiboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (346 aa)
npdANAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. (229 aa)
KQS_03780Probable polysaccharide deacetylase precursor. (256 aa)
defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (195 aa)
folE2GTP cyclohydrolase I. (223 aa)
hutIImidazolonepropionase. (415 aa)
glsAGlutaminase; Belongs to the glutaminase family. (303 aa)
KQS_05210Probable metal-dependent hydrolase superfamily protein precursor. (429 aa)
KQS_05215Probable metal-dependent hydrolase superfamily protein, contains two amidohydrolase related domains. (1007 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (535 aa)
hisIEHistidine biosynthesis bifunctional protein HisIE [Includes: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphatase]; In the N-terminal section; belongs to the PRA-CH family. (206 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (193 aa)
lpxC/fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. (464 aa)
KQS_07155Probable N-acetylmuramoyl-L-alanine amidase precursor. (371 aa)
KQS_07160Probable N-acetylmuramoyl-L-alanine amidase precursor. (365 aa)
ribBABifunctional enzyme : 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (376 aa)
KQS_09875Protein of unknown function. (238 aa)
pyrC2Dihydroorotase. (414 aa)
KQS_10115Arginase family protein; Belongs to the arginase family. (346 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (292 aa)
KQS_10940Putative muramidase. (279 aa)
fjo29Protein of unknown function Fjo29; Belongs to the arginase family. (381 aa)
nadENH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (270 aa)
KQS_12125dCMP deaminase. (143 aa)
Your Current Organism:
Flavobacterium indicum
NCBI taxonomy Id: 1094466
Other names: F. indicum GPTSA100-9 = DSM 17447, Flavobacterium indicum CIP 109464, Flavobacterium indicum DSM 17447, Flavobacterium indicum DSM 17447 = GPTSA100-9, Flavobacterium indicum GPTSA100-9, Flavobacterium indicum GPTSA100-9 = DSM 17447, Flavobacterium sp. GPTSA100-9
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