STRINGSTRING
Tsac_0044 Tsac_0044 murQ murQ Tsac_0162 Tsac_0162 uxaC uxaC Tsac_0218 Tsac_0218 Tsac_0234 Tsac_0234 Tsac_0381 Tsac_0381 arcA arcA arcA-2 arcA-2 Tsac_0775 Tsac_0775 Tsac_1066 Tsac_1066 Tsac_1151 Tsac_1151 Tsac_1219 Tsac_1219 pdxT pdxT uxuA uxuA Tsac_1611 Tsac_1611 nagB nagB dtd dtd Tsac_1717 Tsac_1717 Tsac_1879 Tsac_1879 Tsac_2161 Tsac_2161 Tsac_2168 Tsac_2168 Tsac_2175 Tsac_2175 Tsac_2178 Tsac_2178 Tsac_2232 Tsac_2232 nanE nanE gcvT gcvT gcvH gcvH gcvPA gcvPA gcvPB gcvPB Tsac_2627 Tsac_2627
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
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Your Input:
Tsac_0044KEGG: txy:Thexy_1941 glutamate formiminotransferase; TIGRFAM: Formiminotransferase; PFAM: Formiminotransferase, N-terminal; Formiminotransferase, C-terminal. (298 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (308 aa)
Tsac_0162PFAM: D-galactarate dehydratase/Altronate hydrolase, C-terminal; SAF domain; KEGG: txy:Thexy_2048 altronate dehydratase. (496 aa)
uxaCKEGG: txy:Thexy_2056 Uronate isomerase; HAMAP: Uronate isomerase; PFAM: Uronate isomerase. (466 aa)
Tsac_0218PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; KEGG: txy:Thexy_2094 L-iditol 2-dehydrogenase. (403 aa)
Tsac_0234Fumarylacetoacetate (FAA) hydrolase; PFAM: Fumarylacetoacetase, C-terminal-like; KEGG: txy:Thexy_2108 5-carboxymethyl-2-hydroxymuconate Delta-isomerase. (242 aa)
Tsac_0381KEGG: txy:Thexy_2268 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (282 aa)
arcAPFAM: Amidinotransferase; KEGG: txy:Thexy_0082 arginine deiminase. (406 aa)
arcA-2TIGRFAM: Arginine deiminase; HAMAP: Arginine deiminase; KEGG: txy:Thexy_0173 arginine deiminase; PFAM: Amidinotransferase. (415 aa)
Tsac_0775KEGG: txy:Thexy_0181 Zn-dependent hydrolase of the beta-lactamase fold-like protein protein. (213 aa)
Tsac_1066PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; KEGG: txy:Thexy_1630 2-oxoglutarate synthase. (249 aa)
Tsac_1151KEGG: txy:Thexy_0431 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: Nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. (276 aa)
Tsac_1219KEGG: txy:Thexy_0496 CoA-substrate-specific enzyme activase; TIGRFAM: CoA enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type. (328 aa)
pdxTGlutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (188 aa)
uxuAMannonate dehydratase; Catalyzes the dehydration of D-mannonate. (357 aa)
Tsac_1611Cyclase family protein; PFAM: Putative cyclase; KEGG: txy:Thexy_1104 cyclase family protein. (209 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (256 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (149 aa)
Tsac_1717Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (399 aa)
Tsac_1879KEGG: txy:Thexy_1234 HI0933 family protein; TIGRFAM: HI0933-like protein; PFAM: HI0933-like protein. (405 aa)
Tsac_2161PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; KEGG: txy:Thexy_1616 2-oxoglutarate synthase. (276 aa)
Tsac_2168KEGG: txy:Thexy_1623 methylmalonyl-CoA mutase domain protein; TIGRFAM: Methylmalonyl-CoA mutase, C-terminal; PFAM: Cobalamin (vitamin B12)-binding. (132 aa)
Tsac_2175KEGG: txy:Thexy_1627 alanine dehydrogenase; TIGRFAM: Alanine dehydrogenase/pyridine nucleotide transhydrogenase; PFAM: Alanine dehydrogenase/PNT, C-terminal; Alanine dehydrogenase/PNT, N-terminal; Belongs to the AlaDH/PNT family. (373 aa)
Tsac_2178PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; KEGG: txy:Thexy_1630 2-oxoglutarate synthase. (249 aa)
Tsac_2232KEGG: tbo:Thebr_2145 alanine dehydrogenase; TIGRFAM: Alanine dehydrogenase/pyridine nucleotide transhydrogenase; PFAM: Alanine dehydrogenase/PNT, C-terminal; Alanine dehydrogenase/PNT, N-terminal; Belongs to the AlaDH/PNT family. (372 aa)
nanEN-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (234 aa)
gcvTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (366 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (124 aa)
gcvPAGlycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (451 aa)
gcvPBGlycine dehydrogenase (decarboxylating) subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (483 aa)
Tsac_2627PFAM: Amidohydrolase 1; KEGG: txy:Thexy_0665 amidohydrolase. (385 aa)
Your Current Organism:
Thermoanaerobacterium saccharolyticum
NCBI taxonomy Id: 1094508
Other names: T. saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum str. JW/SL-YS485, Thermoanaerobacterium saccharolyticum strain JW/SL-YS485, Thermoanaerobacterium sp. (strain JW/SL YS485)
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