STRINGSTRING
fis_3 fis_3 gyrA gyrA fis_2 fis_2 fis_1 fis_1 rarA rarA recQ_2 recQ_2 dnaB dnaB parB_4 parB_4 yedK yedK GCA_000236165_03295 GCA_000236165_03295 parC parC GCA_000236165_03188 GCA_000236165_03188 parE parE topA topA dnaG dnaG traC_1 traC_1 GCA_000236165_02094 GCA_000236165_02094 parB_2 parB_2 holC holC smc smc gyrB gyrB ihfB ihfB parB_1 parB_1 priA priA hda hda
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fis_3Unannotated protein; Belongs to the transcriptional regulatory Fis family. (115 aa)
gyrAUnannotated protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (865 aa)
fis_2Unannotated protein; Belongs to the transcriptional regulatory Fis family. (93 aa)
fis_1Unannotated protein; Belongs to the transcriptional regulatory Fis family. (93 aa)
rarAUnannotated protein. (433 aa)
recQ_2Unannotated protein. (607 aa)
dnaBUnannotated protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (460 aa)
parB_4Unannotated protein. (341 aa)
yedKUnannotated protein; Belongs to the SOS response-associated peptidase family. (222 aa)
GCA_000236165_03295Unannotated protein. (363 aa)
parCUnannotated protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (750 aa)
GCA_000236165_03188Unannotated protein. (460 aa)
parEUnannotated protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (627 aa)
topAUnannotated protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (761 aa)
dnaGUnannotated protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (574 aa)
traC_1Unannotated protein. (728 aa)
GCA_000236165_02094Unannotated protein. (347 aa)
parB_2Unannotated protein; Belongs to the ParB family. (263 aa)
holCUnannotated protein. (146 aa)
smcUnannotated protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1164 aa)
gyrBUnannotated protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (805 aa)
ihfBUnannotated protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (103 aa)
parB_1Unannotated protein; Belongs to the ParB family. (291 aa)
priAUnannotated protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (758 aa)
hdaUnannotated protein; Belongs to the DnaA family. HdA subfamily. (230 aa)
Your Current Organism:
Fluoribacter dumoffii
NCBI taxonomy Id: 1094715
Other names: F. dumoffii NY 23, Fluoribacter dumoffii ATCC 33279, Fluoribacter dumoffii NY 23, Fluoribacter dumoffii str. NY 23, Fluoribacter dumoffii strain NY 23
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