15 items (Pseudonocardia sp. EC08061901) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	ALL84795.1	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
	ALL80031.1	Initiation factor 2B subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eIF-2B alpha/beta/delta subunits family. (347 aa)
	metH	B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1203 aa)
	ALL80225.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AB hydrolase superfamily. MetX family. (352 aa)
	ALL80419.1	5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (316 aa)
	ALL80679.1	Dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
	metXA	Homoserine acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (379 aa)
	folD	5,10-methylene-tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (290 aa)
	asd	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (359 aa)
	ALL83087.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AB hydrolase superfamily. MetX family. (354 aa)
	ALL81875.1	Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
	metE	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (767 aa)
	ALL84823.1	Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
	folD-2	Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (283 aa)
	ALL82621.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AB hydrolase superfamily. MetX family. (350 aa)

Your Current Organism:

Pseudonocardia sp. EC08061901

NCBI taxonomy Id: 1096856
Other names: P. sp. EC080619-01, Pseudonocardia sp. EC080619-01

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALL80031.1	ALL80419.1	AD017_00225	AD017_02890	Initiation factor 2B subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eIF-2B alpha/beta/delta subunits family.	5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family.	0.638
ALL80031.1	ALL81875.1	AD017_00225	AD017_13035	Initiation factor 2B subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eIF-2B alpha/beta/delta subunits family.	Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.485
ALL80031.1	ALL84795.1	AD017_00225	AD017_18680	Initiation factor 2B subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eIF-2B alpha/beta/delta subunits family.	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.669
ALL80031.1	ALL84823.1	AD017_00225	AD017_19290	Initiation factor 2B subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eIF-2B alpha/beta/delta subunits family.	Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.485
ALL80031.1	asd	AD017_00225	AD017_11650	Initiation factor 2B subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eIF-2B alpha/beta/delta subunits family.	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	0.466
ALL80031.1	metE	AD017_00225	AD017_15875	Initiation factor 2B subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eIF-2B alpha/beta/delta subunits family.	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	0.485
ALL80031.1	metH	AD017_00225	AD017_26495	Initiation factor 2B subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eIF-2B alpha/beta/delta subunits family.	B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.977
ALL80225.1	ALL82621.1	AD017_01545	AD017_18065	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AB hydrolase superfamily. MetX family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AB hydrolase superfamily. MetX family.	0.908
ALL80225.1	ALL84795.1	AD017_01545	AD017_18680	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AB hydrolase superfamily. MetX family.	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.917
ALL80225.1	metH	AD017_01545	AD017_26495	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AB hydrolase superfamily. MetX family.	B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.598
ALL80225.1	metXA	AD017_01545	AD017_05525	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AB hydrolase superfamily. MetX family.	Homoserine acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.	0.928
ALL80419.1	ALL80031.1	AD017_02890	AD017_00225	5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family.	Initiation factor 2B subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eIF-2B alpha/beta/delta subunits family.	0.638
ALL80419.1	ALL81875.1	AD017_02890	AD017_13035	5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family.	Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.778
ALL80419.1	ALL84795.1	AD017_02890	AD017_18680	5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family.	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.531
ALL80419.1	ALL84823.1	AD017_02890	AD017_19290	5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family.	Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.837
ALL80419.1	folD	AD017_02890	AD017_07290	5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family.	5,10-methylene-tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.934
ALL80419.1	folD-2	AD017_02890	AD017_17740	5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family.	Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.934
ALL80419.1	metE	AD017_02890	AD017_15875	5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family.	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	0.839
ALL80419.1	metH	AD017_02890	AD017_26495	5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family.	B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.998
ALL81875.1	ALL80031.1	AD017_13035	AD017_00225	Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Initiation factor 2B subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eIF-2B alpha/beta/delta subunits family.	0.485