STRINGSTRING
ALL84113.1 ALL84113.1 ALL80069.1 ALL80069.1 pqqE pqqE ALL80075.1 ALL80075.1 ALL84130.1 ALL84130.1 pqqE-2 pqqE-2 trpC trpC hisF hisF hisA hisA ALL80385.1 ALL80385.1 ALL80427.1 ALL80427.1 ALL80565.1 ALL80565.1 bioB bioB dapA dapA dapA-2 dapA-2 dapA-3 dapA-3 rlmN rlmN ALL80872.1 ALL80872.1 ALL80932.1 ALL80932.1 ALL80986.1 ALL80986.1 ALL81046.1 ALL81046.1 ALL81097.1 ALL81097.1 ALL81126.1 ALL81126.1 ALL81164.1 ALL81164.1 ALL81333.1 ALL81333.1 ALL81362.1 ALL81362.1 ALL81379.1 ALL81379.1 pyrD pyrD ALL84519.1 ALL84519.1 leuA leuA trpA trpA ALL81759.1 ALL81759.1 ALL84585.1 ALL84585.1 deoC deoC ALL82049.1 ALL82049.1 thiE thiE thiG thiG ALL82327.1 ALL82327.1 ALL84702.1 ALL84702.1 moaA moaA ALL82388.1 ALL82388.1 ALL82437.1 ALL82437.1 guaB guaB ALL82551.1 ALL82551.1 fbiC fbiC ALL82609.1 ALL82609.1 ALL82803.1 ALL82803.1 ALL82934.1 ALL82934.1 ALL82972.1 ALL82972.1 trpF trpF ALL84879.1 ALL84879.1 dapA-4 dapA-4 ALL83129.1 ALL83129.1 ALL83165.1 ALL83165.1 ALL84910.1 ALL84910.1 lipA lipA ALL84977.1 ALL84977.1 pdxS pdxS ALL83590.1 ALL83590.1 ALL85013.1 ALL85013.1 tpiA tpiA tal tal ALL85037.1 ALL85037.1 ALL83683.1 ALL83683.1 ALL83689.1 ALL83689.1 ALL83784.1 ALL83784.1 ALL84098.1 ALL84098.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ALL84113.1Keto-deoxy-phosphogluconate aldolase; Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
ALL80069.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
pqqEPyrroloquinoline quinone biosynthesis protein PqqE; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (370 aa)
ALL80075.13-hexulose-6-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
ALL84130.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa)
pqqE-2Pyrroloquinoline quinone biosynthesis protein PqqE; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (360 aa)
trpCIndole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (270 aa)
hisFImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa)
hisAPhosphoribosyl isomerase; Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
ALL80385.1Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (305 aa)
ALL80427.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (468 aa)
ALL80565.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (336 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (304 aa)
dapA-2Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (309 aa)
dapA-3Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (342 aa)
rlmNRNA methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (369 aa)
ALL80872.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1126 aa)
ALL80932.13-hydroxy-3-methylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
ALL80986.1Flavin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
ALL81046.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (439 aa)
ALL81097.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
ALL81126.1Nitronate monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
ALL81164.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1126 aa)
ALL81333.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (356 aa)
ALL81362.1Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
ALL81379.12-nitropropane dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
pyrDDiguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (367 aa)
ALL84519.1tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (373 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (598 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (263 aa)
ALL81759.15-dehydro-4-deoxyglucarate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (308 aa)
ALL84585.1N-acetylneuraminate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (227 aa)
ALL82049.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (342 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (227 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (250 aa)
ALL82327.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
ALL84702.12,4-dienoyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (644 aa)
moaAMolybdenum cofactor biosynthesis protein MoeA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (352 aa)
ALL82388.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (308 aa)
ALL82437.1Ethanolamine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
guaBInosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (503 aa)
ALL82551.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
fbiCFO synthase; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (862 aa)
ALL82609.1hydroxymethylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
ALL82803.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
ALL82934.1GltA; Derived by automated computational analysis using gene prediction method: Protein Homology. (1766 aa)
ALL82972.1Tagatose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
trpFPhosphoribosylanthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (206 aa)
ALL84879.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1516 aa)
dapA-4Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa)
ALL83129.1Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (395 aa)
ALL83165.1Lactate 2-monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
ALL84910.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
lipARadical SAM protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (334 aa)
ALL84977.1hydroxymethylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (304 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (305 aa)
ALL83590.1Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
ALL85013.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (232 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (262 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (369 aa)
ALL85037.12-dehydro-3-deoxyphosphogluconate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
ALL83683.11,2-oxophytodienoate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
ALL83689.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
ALL83784.1Deoxyribose-phosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
ALL84098.1NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
Your Current Organism:
Pseudonocardia sp. EC08061901
NCBI taxonomy Id: 1096856
Other names: P. sp. EC080619-01, Pseudonocardia sp. EC080619-01
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