STRINGSTRING
ALL80262.1 ALL80262.1 ALL80337.1 ALL80337.1 ALL80525.1 ALL80525.1 ALL84364.1 ALL84364.1 ALL80972.1 ALL80972.1 ALL81053.1 ALL81053.1 ALL81054.1 ALL81054.1 ALL81055.1 ALL81055.1 ALL81056.1 ALL81056.1 ALL81057.1 ALL81057.1 glyA glyA ALL81062.1 ALL81062.1 ALL81068.1 ALL81068.1 ALL81367.1 ALL81367.1 ALL81370.1 ALL81370.1 ALL81513.1 ALL81513.1 serC serC ALL81647.1 ALL81647.1 asd asd ALL81691.1 ALL81691.1 trpA trpA trpB trpB ALL81792.1 ALL81792.1 ectA ectA ALL82235.1 ALL82235.1 ectC ectC ALL82237.1 ALL82237.1 ALL82268.1 ALL82268.1 ALL82366.1 ALL82366.1 gpmA gpmA ilvA ilvA ALL84795.1 ALL84795.1 ALL84796.1 ALL84796.1 thrB thrB glyA-2 glyA-2 ALL82821.1 ALL82821.1 ALL82840.1 ALL82840.1 ALL83101.1 ALL83101.1 ALL83173.1 ALL83173.1 ALL83175.1 ALL83175.1 ALL83261.1 ALL83261.1 ALL84942.1 ALL84942.1 gcvT gcvT ALL83317.1 ALL83317.1 ALL83433.1 ALL83433.1 ALL83494.1 ALL83494.1 trpB-2 trpB-2 ALL83666.1 ALL83666.1 ALL83744.1 ALL83744.1 ALL83868.1 ALL83868.1 ALL83908.1 ALL83908.1 ALL83909.1 ALL83909.1 ALL84014.1 ALL84014.1 gcvP gcvP gcvH gcvH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALL80262.1Catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; Derived by automated computational analysis using gene prediction method: Protein Homology. (567 aa)
ALL80337.1Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
ALL80525.1Tyramine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (620 aa)
ALL84364.1Threonine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
ALL80972.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
ALL81053.1Sarcosine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (827 aa)
ALL81054.1Sarcosine oxidase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
ALL81055.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (933 aa)
ALL81056.1Sarcosine oxidase subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)
ALL81057.1Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (426 aa)
ALL81062.1Serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (457 aa)
ALL81068.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
ALL81367.1Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
ALL81370.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
ALL81513.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (377 aa)
ALL81647.1Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (359 aa)
ALL81691.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (421 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (263 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (407 aa)
ALL81792.1Glucose-methanol-choline oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
ectA2,4-diaminobutyric acid acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. (163 aa)
ALL82235.1Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (417 aa)
ectCL-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (131 aa)
ALL82237.1Multidrug DMT transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
ALL82268.1Phosphatidylserine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (335 aa)
ALL82366.1Amino acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (244 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (411 aa)
ALL84795.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
ALL84796.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
thrBSerine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (300 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa)
ALL82821.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (536 aa)
ALL82840.1Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
ALL83101.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (319 aa)
ALL83173.1Betaine-aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (490 aa)
ALL83175.1Choline oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
ALL83261.1Serine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
ALL84942.1Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (375 aa)
ALL83317.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. (375 aa)
ALL83433.1Tyramine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (633 aa)
ALL83494.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
trpB-2Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (419 aa)
ALL83666.1Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. (383 aa)
ALL83744.1Sarcosine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
ALL83868.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
ALL83908.1(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
ALL83909.1Sarcosine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
ALL84014.13-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (399 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (958 aa)
gcvHHypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (130 aa)
Your Current Organism:
Pseudonocardia sp. EC08061901
NCBI taxonomy Id: 1096856
Other names: P. sp. EC080619-01, Pseudonocardia sp. EC080619-01
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.