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rpl12 rpl12 rps19p rps19p rps17 rps17 rpl29 rpl29 rps3 rps3 rpl22 rpl22 P186_0128 P186_0128 rpl3 rpl3 rpl23 rpl23 rps14 rps14 P186_0413 P186_0413 P186_0425 P186_0425 rpl37ae rpl37ae rps13 rps13 rps4 rps4 rpl6 rpl6 rpl15 rpl15 rps3ae rps3ae rps15 rps15 rpl10e rpl10e rpl5 rpl5 fusA fusA rps24e rps24e rps8 rps8 rpl32e rpl32e rpl19e rpl19e rpl18 rpl18 rpl7ae rpl7ae rpl24e rpl24e rps28e rps28e eif5a eif5a rpl21e rpl21e rps4e rps4e rpl24 rpl24 rpl14 rpl14 rps11 rps11 rpl40e rpl40e rpl10 rpl10 rpl1 rpl1 rpl11 rpl11 rpl18a rpl18a rpl31e rpl31e rps19e rps19e rpl44e rpl44e rpl34e rpl34e rps10 rps10 rpl30e rpl30e rps12 rps12 P186_2185 P186_2185 rpl13 rpl13 rps9 rps9 rps7 rps7 rpl2 rpl2 P186_2280 P186_2280 rps2 rps2 rpl14e rpl14e eif1a eif1a rpl30 rpl30 rps5 rps5 rps6e rps6e
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpl1250S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (109 aa)
rps19p30S ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (162 aa)
rps17Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (146 aa)
rpl29Hypothetical protein; Belongs to the universal ribosomal protein uL29 family. (68 aa)
rps330S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (218 aa)
rpl2250S ribosomal protein L22P; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (188 aa)
P186_012850S ribosomal protein L15e. (180 aa)
rpl350S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (338 aa)
rpl23Ribosomal protein L25/L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (81 aa)
rps1430S ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (54 aa)
P186_041330S ribosomal protein S26e. (98 aa)
P186_042530S ribosomal protein S25e. (110 aa)
rpl37ae50S ribosomal protein L37Ae; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily. (101 aa)
rps1330S ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (149 aa)
rps430S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (159 aa)
rpl6Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (196 aa)
rpl1550S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (156 aa)
rps3ae30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (235 aa)
rps1530S ribosomal protein S15P. (151 aa)
rpl10e50S ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family. (181 aa)
rpl550S ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa)
fusATranslation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (740 aa)
rps24eRibosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. (121 aa)
rps830S ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (143 aa)
rpl32e50S ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family. (152 aa)
rpl19eRibosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (147 aa)
rpl1850S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (205 aa)
rpl7ae50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (153 aa)
rpl24eRibosomal protein L24E; Binds to the 23S rRNA. (61 aa)
rps28e30S ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (77 aa)
eif5aTranslation initiation factor 5A (eIF-5A) (Hypusine-containing protein); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (132 aa)
rpl21eRibosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (100 aa)
rps4e30S ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family. (238 aa)
rpl2450S ribosomal protein L24P; Located at the polypeptide exit tunnel on the outside of the subunit. (122 aa)
rpl1450S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (144 aa)
rps11Ribosomal protein S11; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (141 aa)
rpl40e50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. (53 aa)
rpl10Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (344 aa)
rpl150S ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (222 aa)
rpl11Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (167 aa)
rpl18aRibosomal protein LX. (78 aa)
rpl31eRibosomal protein L31; Belongs to the ribosomal protein L31e family. (97 aa)
rps19e30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (158 aa)
rpl44e50S ribosomal protein L44e; Binds to the 23S rRNA. (91 aa)
rpl34eRibosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family. (88 aa)
rps1030S ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (127 aa)
rpl30eRibosomal protein L7Ae/L30e/S12e/Gadd45; Belongs to the eukaryotic ribosomal protein eL30 family. (101 aa)
rps1230S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa)
P186_218550S ribosomal protein L18e. (88 aa)
rpl13Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (187 aa)
rps9Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (146 aa)
rps730S ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (209 aa)
rpl250S ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (259 aa)
P186_228030S ribosomal protein S17e. (53 aa)
rps230S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (208 aa)
rpl14e50S ribosomal protein L14e; Belongs to the eukaryotic ribosomal protein eL14 family. (103 aa)
eif1aTranslation initiation factor IF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (97 aa)
rpl3050S ribosomal protein L30P. (177 aa)
rps530S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (202 aa)
rps6e30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. (149 aa)
Your Current Organism:
Pyrobaculum ferrireducens
NCBI taxonomy Id: 1104324
Other names: DSM 28942, P. ferrireducens, Pyrobaculum ferrireducens Slobodkina et al. 2015, VKM B-2856
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