node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | PIIN_04709 | G4T920 | G4THI1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Related to RAD2-structure-specific nuclease of the nucleotide excision repairosome. | 0.513 |
FEN1 | PIIN_06722 | G4T920 | G4TN92 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Related to EXO1-exonuclease which interacts with Msh2p. | 0.877 |
FEN1 | PIIN_07867 | G4T920 | G4TRG7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Related to DNA repair endonuclease rad2. | 0.706 |
FEN1 | PIIN_10044 | G4T920 | G4TXK1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.472 |
PIIN_01260 | PIIN_06695 | G4T819 | G4TN59 | annotation not available | annotation not available | 0.867 |
PIIN_04709 | FEN1 | G4THI1 | G4T920 | Related to RAD2-structure-specific nuclease of the nucleotide excision repairosome. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.513 |
PIIN_04709 | PIIN_06722 | G4THI1 | G4TN92 | Related to RAD2-structure-specific nuclease of the nucleotide excision repairosome. | Related to EXO1-exonuclease which interacts with Msh2p. | 0.452 |
PIIN_04709 | PIIN_07867 | G4THI1 | G4TRG7 | Related to RAD2-structure-specific nuclease of the nucleotide excision repairosome. | Related to DNA repair endonuclease rad2. | 0.582 |
PIIN_04709 | PIIN_08962 | G4THI1 | G4TUI9 | Related to RAD2-structure-specific nuclease of the nucleotide excision repairosome. | Related to RAD27-ssDNA endonuclease and 5`-3`exonuclease. | 0.497 |
PIIN_04709 | PIIN_10044 | G4THI1 | G4TXK1 | Related to RAD2-structure-specific nuclease of the nucleotide excision repairosome. | Uncharacterized protein. | 0.411 |
PIIN_06695 | PIIN_01260 | G4TN59 | G4T819 | annotation not available | annotation not available | 0.867 |
PIIN_06695 | PIIN_06814 | G4TN59 | G4TNI7 | annotation not available | Probable DIS3 3`-5` exoribonuclease required for 3` end formation of 5.8S rRNA; Belongs to the RNR ribonuclease family. | 0.655 |
PIIN_06722 | FEN1 | G4TN92 | G4T920 | Related to EXO1-exonuclease which interacts with Msh2p. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.877 |
PIIN_06722 | PIIN_04709 | G4TN92 | G4THI1 | Related to EXO1-exonuclease which interacts with Msh2p. | Related to RAD2-structure-specific nuclease of the nucleotide excision repairosome. | 0.452 |
PIIN_06722 | PIIN_07867 | G4TN92 | G4TRG7 | Related to EXO1-exonuclease which interacts with Msh2p. | Related to DNA repair endonuclease rad2. | 0.744 |
PIIN_06722 | PIIN_08962 | G4TN92 | G4TUI9 | Related to EXO1-exonuclease which interacts with Msh2p. | Related to RAD27-ssDNA endonuclease and 5`-3`exonuclease. | 0.822 |
PIIN_06722 | PIIN_10044 | G4TN92 | G4TXK1 | Related to EXO1-exonuclease which interacts with Msh2p. | Uncharacterized protein. | 0.479 |
PIIN_06814 | PIIN_06695 | G4TNI7 | G4TN59 | Probable DIS3 3`-5` exoribonuclease required for 3` end formation of 5.8S rRNA; Belongs to the RNR ribonuclease family. | annotation not available | 0.655 |
PIIN_07867 | FEN1 | G4TRG7 | G4T920 | Related to DNA repair endonuclease rad2. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.706 |
PIIN_07867 | PIIN_04709 | G4TRG7 | G4THI1 | Related to DNA repair endonuclease rad2. | Related to RAD2-structure-specific nuclease of the nucleotide excision repairosome. | 0.582 |