STRINGSTRING
AFA71166.1 AFA71166.1 AFA71572.1 AFA71572.1 AFA71573.1 AFA71573.1 AFA71574.1 AFA71574.1 AFA71575.1 AFA71575.1 AFA71576.1 AFA71576.1 pntA pntA AFA71578.1 AFA71578.1 pntB pntB AFA72581.1 AFA72581.1 coaA coaA npdA npdA acpS acpS sthA sthA folC folC coaD coaD ribF ribF AFA73121.1 AFA73121.1 coaBC coaBC ribD ribD AFA73296.1 AFA73296.1 ribE ribE ribBA ribBA ribH ribH AFA73300.1 AFA73300.1 AFA73301.1 AFA73301.1 AFA73303.1 AFA73303.1 AFA73304.1 AFA73304.1 whiA whiA coaE coaE AFA73659.1 AFA73659.1 AFA73660.1 AFA73660.1 nadC nadC nadA nadA AFA73749.1 AFA73749.1 AFA73750.1 AFA73750.1 AFA73751.1 AFA73751.1 bioB bioB bioD bioD bioF bioF bioA bioA AFA73756.1 AFA73756.1 AFA73757.1 AFA73757.1 panB panB nadD nadD folP1 folP1 nudC nudC AFA75008.1 AFA75008.1 nadE nadE AFA75231.1 AFA75231.1 coaX coaX panD panD panC panC AFA75331.1 AFA75331.1 AFA75332.1 AFA75332.1 AFA75333.1 AFA75333.1 folK folK folB folB folP2 folP2 folE folE AFA75592.1 AFA75592.1 panE panE AFA75828.1 AFA75828.1 AFA75967.1 AFA75967.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFA71166.1Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (318 aa)
AFA71572.1Putative esterase. (318 aa)
AFA71573.1Putative FAD-binding dehydrogenase. (489 aa)
AFA71574.1Oxidoreductase, molybdopterin binding protein. (540 aa)
AFA71575.1Hypothetical protein. (525 aa)
AFA71576.1Hypothetical protein. (418 aa)
pntANAD(P) transhydrogenase subunit alpha. (361 aa)
AFA71578.1Putative oxidoreductase. (101 aa)
pntBNAD(P) transhydrogenase subunit beta. (514 aa)
AFA72581.1Alkaline phosphatase. (538 aa)
coaAPantothenate kinase CoaA. (313 aa)
npdANAD-dependent deacetylase NpdA; Belongs to the sirtuin family. Class III subfamily. (277 aa)
acpSHolo-[acyl-carrier-protein] synthase AcpS; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (131 aa)
sthASoluble pyridine nucleotide transhydrogenase SthA. (482 aa)
folCDihydrofolate synthase / folylpolyglutamate synthase FolC. (545 aa)
coaDPhosphopantetheine adenylyltransferase CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (162 aa)
ribFRiboflavin biosynthesis protein RibF; Belongs to the ribF family. (322 aa)
AFA73121.1Putative alkaline phosphatase. (588 aa)
coaBCCoenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (432 aa)
ribDRiboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (343 aa)
AFA73296.1Hypothetical protein. (91 aa)
ribERiboflavin synthase alpha chain RibE. (220 aa)
ribBARiboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (449 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase RibH; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (171 aa)
AFA73300.1Protein of unknown function DUF2581. (152 aa)
AFA73301.1Putative S-adenosyl-L-methionine-dependent methyltransferase; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. (291 aa)
AFA73303.1Putative nucleotide-binding protein; Displays ATPase and GTPase activities. (313 aa)
AFA73304.1Protein of unknown function UPF0052; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (334 aa)
whiAPutative sporulation transcription regulator WhiA; Involved in cell division and chromosome segregation. (327 aa)
coaEdephospho-CoA kinase CoaE; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (298 aa)
AFA73659.1Hypothetical protein. (186 aa)
AFA73660.1Methyltransferase type 11. (282 aa)
nadCNicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (299 aa)
nadAQuinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (353 aa)
AFA73749.1NUDIX hydrolase. (221 aa)
AFA73750.1Hypothetical protein. (204 aa)
AFA73751.1Hypothetical protein. (90 aa)
bioBBiotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (346 aa)
bioDDethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (248 aa)
bioF8-amino-7-oxononanoate synthase. (396 aa)
bioAAdenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (432 aa)
AFA73756.1Transcriptional regulator, TetR family. (189 aa)
AFA73757.1Acyltransferase 3. (730 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (298 aa)
nadDNicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (245 aa)
folP1Dihydropteroate synthase FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (299 aa)
nudCNADH pyrophosphatase NudC. (308 aa)
AFA75008.1Putative alkylated DNA repair protein. (212 aa)
nadENAD+ synthase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (675 aa)
AFA75231.1Putative secreted alkaline phosphatase. (542 aa)
coaXType III pantothenate kinase CoaX; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (266 aa)
panDAspartate 1-decarboxylase PanD; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (144 aa)
panCPantothenate synthetase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (306 aa)
AFA75331.1Putative oxidoreductase. (352 aa)
AFA75332.1Hypothetical protein. (425 aa)
AFA75333.1Putative membrane protein, DUF3180. (180 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK. (185 aa)
folBDihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (123 aa)
folP2Dihydropteroate synthase FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (295 aa)
folEGTP cyclohydrolase 1. (204 aa)
AFA75592.1CinA-like protein; Belongs to the CinA family. (157 aa)
panE2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (301 aa)
AFA75828.1CinA domain-containing protein; Belongs to the CinA family. (439 aa)
AFA75967.1Hypothetical protein. (700 aa)
Your Current Organism:
Gordonia polyisoprenivorans
NCBI taxonomy Id: 1112204
Other names: G. polyisoprenivorans VH2, Gordonia polyisoprenivorans VH2, Gordonia polyisoprenivorans str. VH2, Gordonia polyisoprenivorans strain VH2
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