STRINGSTRING
AFA71166.1 AFA71166.1 AFA72581.1 AFA72581.1 coaA coaA acpS acpS folC folC coaD coaD AFA73121.1 AFA73121.1 coaBC coaBC coaE coaE panB panB folP1 folP1 AFA75008.1 AFA75008.1 AFA75231.1 AFA75231.1 coaX coaX panD panD panC panC AFA75331.1 AFA75331.1 AFA75332.1 AFA75332.1 AFA75333.1 AFA75333.1 folK folK folB folB folP2 folP2 folE folE panE panE AFA75967.1 AFA75967.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFA71166.1Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (318 aa)
AFA72581.1Alkaline phosphatase. (538 aa)
coaAPantothenate kinase CoaA. (313 aa)
acpSHolo-[acyl-carrier-protein] synthase AcpS; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (131 aa)
folCDihydrofolate synthase / folylpolyglutamate synthase FolC. (545 aa)
coaDPhosphopantetheine adenylyltransferase CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (162 aa)
AFA73121.1Putative alkaline phosphatase. (588 aa)
coaBCCoenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (432 aa)
coaEdephospho-CoA kinase CoaE; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (298 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (298 aa)
folP1Dihydropteroate synthase FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (299 aa)
AFA75008.1Putative alkylated DNA repair protein. (212 aa)
AFA75231.1Putative secreted alkaline phosphatase. (542 aa)
coaXType III pantothenate kinase CoaX; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (266 aa)
panDAspartate 1-decarboxylase PanD; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (144 aa)
panCPantothenate synthetase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (306 aa)
AFA75331.1Putative oxidoreductase. (352 aa)
AFA75332.1Hypothetical protein. (425 aa)
AFA75333.1Putative membrane protein, DUF3180. (180 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK. (185 aa)
folBDihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (123 aa)
folP2Dihydropteroate synthase FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (295 aa)
folEGTP cyclohydrolase 1. (204 aa)
panE2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (301 aa)
AFA75967.1Hypothetical protein. (700 aa)
Your Current Organism:
Gordonia polyisoprenivorans
NCBI taxonomy Id: 1112204
Other names: G. polyisoprenivorans VH2, Gordonia polyisoprenivorans VH2, Gordonia polyisoprenivorans str. VH2, Gordonia polyisoprenivorans strain VH2
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.