STRINGSTRING
uppS2 uppS2 gpsA2 gpsA2 AFA74064.1 AFA74064.1 AFA74083.1 AFA74083.1 lpqW lpqW AFA74146.1 AFA74146.1 AFA74194.1 AFA74194.1 AFA74394.1 AFA74394.1 AFA74406.1 AFA74406.1 AFA74407.1 AFA74407.1 AFA74434.1 AFA74434.1 AFA74501.1 AFA74501.1 AFA74526.1 AFA74526.1 AFA74586.1 AFA74586.1 AFA74602.1 AFA74602.1 AFA74603.1 AFA74603.1 AFA74604.1 AFA74604.1 AFA74681.1 AFA74681.1 AFA74682.1 AFA74682.1 AFA74709.1 AFA74709.1 AFA74731.1 AFA74731.1 AFA74743.1 AFA74743.1 AFA74792.1 AFA74792.1 AFA74800.1 AFA74800.1 cfa2 cfa2 AFA74804.1 AFA74804.1 AFA74816.1 AFA74816.1 pfaA pfaA AFA74842.1 AFA74842.1 AFA74967.1 AFA74967.1 AFA74987.1 AFA74987.1 wSD2 wSD2 AFA75051.1 AFA75051.1 AFA75110.1 AFA75110.1 hsaB hsaB AFA75133.1 AFA75133.1 AFA75184.1 AFA75184.1 AFA75225.1 AFA75225.1 AFA75243.1 AFA75243.1 AFA75272.1 AFA75272.1 AFA75275.1 AFA75275.1 AFA75303.1 AFA75303.1 AFA75316.1 AFA75316.1 AFA75461.1 AFA75461.1 AFA75482.1 AFA75482.1 AFA75493.1 AFA75493.1 AFA75495.1 AFA75495.1 wSD3 wSD3 AFA75675.1 AFA75675.1 cfa3 cfa3 AFA75774.1 AFA75774.1 AFA75783.1 AFA75783.1 AFA75816.1 AFA75816.1 AFA75817.1 AFA75817.1 AFA75821.1 AFA75821.1 crtB crtB idi idi AFA75917.1 AFA75917.1 AFA75922.1 AFA75922.1 AFA75927.1 AFA75927.1 AFA76005.1 AFA76005.1 plsB plsB AFA73927.1 AFA73927.1 wSD1 wSD1 kasA kasA acpM acpM fabD fabD AFA73898.1 AFA73898.1 oatA oatA AFA73896.1 AFA73896.1 lipA lipA AFA73837.1 AFA73837.1 pimB pimB AFA73818.1 AFA73818.1 AFA73811.1 AFA73811.1 AFA73757.1 AFA73757.1 AFA73744.1 AFA73744.1 AFA73705.1 AFA73705.1 ntaB ntaB AFA73560.1 AFA73560.1 pds pds AFA73413.1 AFA73413.1 AFA73391.1 AFA73391.1 AFA73389.1 AFA73389.1 inhA inhA AFA73359.1 AFA73359.1 AFA73348.1 AFA73348.1 AFA73345.1 AFA73345.1 AFA73342.1 AFA73342.1 qor qor pimA pimA AFA73226.1 AFA73226.1 AFA73225.1 AFA73225.1 AFA73221.1 AFA73221.1 dxs dxs suhB1 suhB1 pgsA pgsA AFA73113.1 AFA73113.1 AFA73112.1 AFA73112.1 AFA73078.1 AFA73078.1 ispG ispG dxr dxr cdsA cdsA acpS acpS AFA72937.1 AFA72937.1 AFA72917.1 AFA72917.1 AFA72759.1 AFA72759.1 AFA72642.1 AFA72642.1 ispH ispH AFA72520.1 AFA72520.1 glmU glmU fabH2 fabH2 fabH1 fabH1 ispE ispE AFA72277.1 AFA72277.1 AFA72238.1 AFA72238.1 AFA72228.1 AFA72228.1 AFA72182.1 AFA72182.1 AFA72181.1 AFA72181.1 AFA72167.1 AFA72167.1 AFA72102.1 AFA72102.1 AFA72075.1 AFA72075.1 ispF ispF ispD ispD AFA71962.1 AFA71962.1 psd psd AFA71919.1 AFA71919.1 AFA71790.1 AFA71790.1 AFA71748.1 AFA71748.1 AFA71694.1 AFA71694.1 AFA71686.1 AFA71686.1 AFA71666.1 AFA71666.1 AFA71561.1 AFA71561.1 AFA71529.1 AFA71529.1 AFA71517.1 AFA71517.1 AFA71489.1 AFA71489.1 AFA71488.1 AFA71488.1 AFA71483.1 AFA71483.1 AFA71469.1 AFA71469.1 AFA71465.1 AFA71465.1 AFA71458.1 AFA71458.1 AFA71392.1 AFA71392.1 AFA71290.1 AFA71290.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
uppS2Undecaprenyl pyrophosphate synthase 2; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (273 aa)
gpsA2Glycerol-3-phosphate dehydrogenase [NAD(P)+] 2; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (337 aa)
AFA74064.11-acyl-sn-glycerol-3-phosphate acyltransferase. (357 aa)
AFA74083.1Zinc-binding alcohol dehydrogenase. (318 aa)
lpqWMonoacyl phosphatidylinositol tetramannoside-binding protein LpqW. (628 aa)
AFA74146.11-acyl-sn-glycerol-3-phosphate acyltransferase. (226 aa)
AFA74194.1Putative diacylglycerol kinase. (442 aa)
AFA74394.1Diacylglycerol kinase-like protein. (315 aa)
AFA74406.1Flavin reductase like domain-containing protein. (175 aa)
AFA74407.1Zinc-binding alcohol dehydrogenase family protein. (349 aa)
AFA74434.1Putative zinc binding alcohol dehydrogenase. (333 aa)
AFA74501.1Putative wax ester synthase/acyl-CoA:diacylglycerol acyltransferase. (459 aa)
AFA74526.1Putative hydrolase, alpha/beta fold family. (364 aa)
AFA74586.1Putative non-ribosomal peptide synthetase. (4618 aa)
AFA74602.1Putative non-ribosomal peptide synthetase. (4583 aa)
AFA74603.1Putative non-ribosomal peptide synthetase. (13437 aa)
AFA74604.1Putative non-ribosomal peptide synthetase. (2759 aa)
AFA74681.1Putative secreted esterase. (323 aa)
AFA74682.1Putative CDP-diacylglycerol pyrophosphatase. (293 aa)
AFA74709.1Putative acyl-CoA synthetase. (531 aa)
AFA74731.1Putative zinc binding alcohol dehydrogenase. (322 aa)
AFA74743.1Putative acyl-ACP thioesterase. (292 aa)
AFA74792.1Putative transmembrane protein. (458 aa)
AFA74800.1Putative AMP-dependent synthetase/ligase. (614 aa)
cfa2Cyclopropane-fatty-acyl-phospholipid synthase Cfa. (322 aa)
AFA74804.1Putative phosphopantetheine-binding protein. (102 aa)
AFA74816.1Putative beta-ketoacyl synthase. (717 aa)
pfaAPolyketide-type polyunsaturated fatty acid synthase PfaA. (2229 aa)
AFA74842.1Putative carboxyl transferase. (644 aa)
AFA74967.1Putative o-succinylbenzoate--CoA ligase. (576 aa)
AFA74987.1Flavin reductase like domain-containing protein. (192 aa)
wSD2O-acyltransferase WSD; Belongs to the long-chain O-acyltransferase family. (467 aa)
AFA75051.1Putative fatty acid desaturase. (330 aa)
AFA75110.1Putative diacylglycerol O-acyltransferase. (489 aa)
hsaBFlavin-dependent monooxygenase, reductase subunit HsaB. (191 aa)
AFA75133.1Putative FMN-dependent oxidoreductase. (170 aa)
AFA75184.1Putative zinc-binding oxidoreductase. (288 aa)
AFA75225.1Putative integral membrane protein. (728 aa)
AFA75243.1Putative secreted esterase. (322 aa)
AFA75272.1Putative fatty-acid--CoA ligase. (511 aa)
AFA75275.1Putative 2-nitropropane dioxygenase. (379 aa)
AFA75303.1Hypothetical protein. (123 aa)
AFA75316.1Putative fatty-acid--CoA ligase. (535 aa)
AFA75461.1Putative 3-oxoacyl-[acyl-carrier-protein] synthase. (348 aa)
AFA75482.1Putative quinone oxidoreductase, YhdH/YhfP family. (335 aa)
AFA75493.1Putative membrane-bound calcineurin-like phosphoesterase. (381 aa)
AFA75495.1Flavin reductase-like domain-containing protein. (167 aa)
wSD3O-acyltransferase WSD; Belongs to the long-chain O-acyltransferase family. (473 aa)
AFA75675.1Putative secreted ceramidase. (690 aa)
cfa3Cyclopropane-fatty-acyl-phospholipid synthase Cfa; Cyclopropane synthetase. (440 aa)
AFA75774.1Putative acyltransferase. (381 aa)
AFA75783.1FAD dependent oxidoreductase. (614 aa)
AFA75816.1Putative geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (369 aa)
AFA75817.1Putative monooxygenase. (236 aa)
AFA75821.1Phytoene desaturase. (526 aa)
crtBPhytoene synthase CrtB; Geranylgeranyl-diphosphate geranylgeranyltransferase. (307 aa)
idiIsopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (185 aa)
AFA75917.1Inositol-3-phosphate synthase. (338 aa)
AFA75922.1Putative alcohol dehydrogenase. (313 aa)
AFA75927.1AMP-binding domain-containing protein. (473 aa)
AFA76005.1Fatty acid hydroxylase. (364 aa)
plsBGlycerol-3-phosphate acyltransferase PlsB; Belongs to the GPAT/DAPAT family. (731 aa)
AFA73927.11-acyl-sn-glycerol-3-phosphate acyltransferase alpha; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (495 aa)
wSD1O-acyltransferase WSD. (474 aa)
kasA3-oxoacyl-[acyl-carrier-protein] synthase 1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (405 aa)
acpMMeromycolate extension acyl carrier protein AcpM; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (101 aa)
fabDMalonyl CoA-acyl carrier protein transacylase FabD. (287 aa)
AFA73898.1Hypothetical protein. (294 aa)
oatAO-acetyltransferase OatA. (974 aa)
AFA73896.1Hypothetical protein. (294 aa)
lipALipoyl synthase LipA; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (327 aa)
AFA73837.1Putative phosphatidic acid phosphatase type 2. (505 aa)
pimBGDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase PimB. (375 aa)
AFA73818.11-acyl-sn-glycerol-3-phosphate acyltransferase. (235 aa)
AFA73811.1Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (384 aa)
AFA73757.1Acyltransferase 3. (730 aa)
AFA73744.1Hypothetical protein. (508 aa)
AFA73705.1Hypothetical protein. (492 aa)
ntaBNitrilotriacetate monooxygenase component B. (163 aa)
AFA73560.1Hypothetical protein. (147 aa)
pdsPhytoene dehydrogenase Pds. (449 aa)
AFA73413.1Putative membrane protein. (490 aa)
AFA73391.1Putative non-ribosomal peptide synthetase. (1059 aa)
AFA73389.1Putative non-ribosomal peptide synthetase. (4485 aa)
inhAEnoyl-reductase (NADH). (277 aa)
AFA73359.1Putative 3-oxoacyl-[acyl-carrier-protein] synthase. (350 aa)
AFA73348.1Putative glycosyltransferase. (290 aa)
AFA73345.1Putative non-ribosomal peptide synthetase. (856 aa)
AFA73342.1Putative glycosyltransferase. (286 aa)
qorQuinone oxidoreductase Qor. (321 aa)
pimAGDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase PimA. (374 aa)
AFA73226.1Putative acyltransferase. (311 aa)
AFA73225.1Putative phosphatidylinositol synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (228 aa)
AFA73221.1Putative transmembrane protein. (513 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (663 aa)
suhB1Inositol monophosphate phosphatase SuhB; Belongs to the inositol monophosphatase superfamily. (312 aa)
pgsACDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase PgsA; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (234 aa)
AFA73113.1Putative phosphopantetheine-binding protein. (127 aa)
AFA73112.1AMP-binding domain-containing protein. (1164 aa)
AFA73078.1Putative fatty acid desaturase. (331 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (402 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (390 aa)
cdsAPhosphatidate cytidylyltransferase CdsA; Belongs to the CDS family. (314 aa)
acpSHolo-[acyl-carrier-protein] synthase AcpS; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (131 aa)
AFA72937.1Putative fatty acid synthase. (3085 aa)
AFA72917.1Putative NAD(P)H quinone oxidoreductase. (324 aa)
AFA72759.1Putative phenol hydroxylase, reductase component. (195 aa)
AFA72642.1Putative ATP-binding protein. (148 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase IspH; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (317 aa)
AFA72520.1Putative cyclopropane-fatty-acyl-phospholipid synthase. (416 aa)
glmUBifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (500 aa)
fabH23-oxoacyl-[acyl-carrier-protein] synthase 3 FabH; Belongs to the thiolase-like superfamily. FabH family. (356 aa)
fabH13-oxoacyl-[acyl-carrier-protein] synthase 3 FabH; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (338 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (319 aa)
AFA72277.1Putative mannosyltransferase. (784 aa)
AFA72238.1Polyprenyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (360 aa)
AFA72228.1Glycosyl transferase, group 1. (387 aa)
AFA72182.1Putative exopolysaccharide synthesis protein. (462 aa)
AFA72181.1Putative acyltransferase. (390 aa)
AFA72167.1Putative acyltransferase. (690 aa)
AFA72102.1Putative phospholipid/glycerol acyltransferase. (384 aa)
AFA72075.1Putative membrane protein. (555 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (183 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase IspD; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (242 aa)
AFA71962.1Putative NADPH-flavin oxidoreductase. (157 aa)
psdPhosphatidylserine decarboxylase proenzyme Psd; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (245 aa)
AFA71919.1Putative CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (349 aa)
AFA71790.1Putative calcineurin-like phosphoesterase. (332 aa)
AFA71748.1Putative transmembrane protein. (430 aa)
AFA71694.1Non-ribosomal peptide synthetase. (3809 aa)
AFA71686.1Non-ribosomal peptide synthetase. (1297 aa)
AFA71666.1Putative MaoC-like dehydratase. (320 aa)
AFA71561.1Putative FAD-binding dehydrogenase. (553 aa)
AFA71529.1Putative quinone oxidoreductase. (334 aa)
AFA71517.1Putative transmembrane protein. (485 aa)
AFA71489.1Putative polyketide synthase. (1775 aa)
AFA71488.1Putative long-chain-fatty-acid--AMP ligase. (640 aa)
AFA71483.1Putative esterase. (340 aa)
AFA71469.1Phospholipid/glycerol acyltransferase. (264 aa)
AFA71465.1Phospholipid/glycerol acyltransferase. (259 aa)
AFA71458.1Putative zinc-dependent dehydrogenase. (302 aa)
AFA71392.1Glycosyl transferase, family 39. (685 aa)
AFA71290.1Flavin reductase like domain-containing protein. (161 aa)
Your Current Organism:
Gordonia polyisoprenivorans
NCBI taxonomy Id: 1112204
Other names: G. polyisoprenivorans VH2, Gordonia polyisoprenivorans VH2, Gordonia polyisoprenivorans str. VH2, Gordonia polyisoprenivorans strain VH2
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